Intraneural perineurioma of the tongue: report of a case and review of the literature

Akio Tanaka; Patricia González Alva; Yuji Miyazaki; Noriaki Yoshida; Tadayoshi Kaneko; Yuka Oku; Eri Okamoto; Hideaki Sakashita; Kaoru Kusama

doi:10.3353/omp.13.71

Case Report

Intraneural perineurioma of the tongue: report of a case and review of the literature

Akio Tanaka, Patricia González Alva, Yuji Miyazaki, Noriaki Yoshida, Tadayoshi Kaneko, Yuka Oku, Eri Okamoto, Hideaki Sakashita, Kaoru Kusama

Author information

Akio Tanaka
Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Patricia González Alva
Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Yuji Miyazaki
Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Noriaki Yoshida
Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Tadayoshi Kaneko
Department of Oral and Maxillofacial Surgery, Tokyo Medical University
Yuka Oku
Division of Oral and Maxillofacial Surgery II, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Eri Okamoto
Division of Oral and Maxillofacial Surgery II, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Hideaki Sakashita
Division of Oral and Maxillofacial Surgery II, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
Kaoru Kusama
Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry

Keywords: intraneural perineurioma, peripheral nerve sheath tumor, perineurial cell

JOURNAL FREE ACCESS

2009 Volume 13 Issue 2 Pages 71-74

DOI https://doi.org/10.3353/omp.13.71

Details

Abstract

An intraneural perineurioma arising in the tongue of a 34-year-old woman is presented. Histologically, the tumor was composed of numerous pseudo-onion bulb structures, formed by whorled proliferation of spindle cells around axons. Immunohistochemically, the spindle cells were positive for epithelial membrane antigen (EMA) but negative for S-100 protein, indicating that the tumors cells were derived from perineurial cells.

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