Efficacy of entecavir treatment among chronic hepatitis B nucleos(t)ide-naïve and -experienced patients

Authors

KADİR ÇAĞATAY BİÇER
ALPAY ARI
VECDİ EVREN GENÇ
SİBEL ÖZSU CAYMAZ
MELTEM AVCI
FATMA BAL

DOI

10.3906/sag-1309-78

Abstract

To evaluate the efficacy of entecavir (ETV) among chronic hepatitis B (CHB) nucleos(t)ide-naïve and -experienced patients in clinical practice. Materials and methods: In this retrospective study 85 CHB patients who had been receiving ETV and who attended our clinic since 2007 were included. Fifty patients were nucleos(t)ide analogue (NA)-naïve. Factors including sex, positive HBeAg, baseline HBV DNA level, baseline alanine aminotransferase level, and prior lamivudine (LAM) resistance were evaluated in terms of their predictive role in treatment response, which was defined as a serum HBV DNA decrease of

Keywords

Chronic hepatitis B virus infection, entecavir, efficacy, predictive factors, viral response, lamivudine resistance

First Page

99

Last Page

104

Recommended Citation

BİÇER, KADİR ÇAĞATAY; ARI, ALPAY; GENÇ, VECDİ EVREN; CAYMAZ, SİBEL ÖZSU; AVCI, MELTEM; and BAL, FATMA (2015) "Efficacy of entecavir treatment among chronic hepatitis B nucleos(t)ide-naïve and -experienced patients," Turkish Journal of Medical Sciences: Vol. 45: No. 1, Article 16. https://doi.org/10.3906/sag-1309-78
Available at: https://journals.tubitak.gov.tr/medical/vol45/iss1/16