Serum pentadecanoic acid (15:0), a short-term marker of dairy food intake, is inversely associated with incident type 2 diabetes and its underlying disorders123
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From the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada (IDS and AJH); Lipomics, a Division of Metabolon Inc., West Sacramento, CA (SMW); the Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC (ADL); the Division of Public Health Sciences, School of Medicine, Wake Forest University, Winston-Salem, NC (LEW); Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO (MJR); the Division of Clinical Epidemiology, University of Texas Health Sciences Center, San Antonio, TX (SMH and CL); the Department of Medicine and Dalla Lana School of Public Health, University of Toronto, Toronto, Canada (AJH); and Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Canada (AJH).
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Supported by a contribution from the Dairy Research Cluster Initiative (Dairy Farmers of Canada, Agriculture and Agri-Food Canada, the Canadian Dairy Network, and the Canadian Dairy Commission). IDS is supported by the University of Toronto Banting & Best Diabetes Centre, Tamarack Graduate Award in Diabetes Research, and Dairy Farmers of Canada (Ontario Student Opportunity Trust Funds).
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Address correspondence to AJ Hanley, Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, FitzGerald Building, 150 College Street, Toronto, ON, Canada M5S 3E2. E-mail: [email protected].
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Abbreviations used: DI, disposition index; FFQ, food-frequency questionnaire; FSIGT, frequently sampled intravenous-glucose-tolerance test; IRAS, Insulin Resistance Atherosclerosis Study; SI, insulin sensitivity index; TFA, trans fatty acid.