Fruit, vegetables, and colorectal cancer risk: the European Prospective Investigation into Cancer and Nutrition123
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From the National Institute for Public Health and the Environment, Bilthoven, Netherlands (FJBvD, HBB-D-M, MMR, HCB, and MCO); the Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, Netherlands (FJBvD, PHMP, and CHvG); the International Agency for Research on Cancer, Lyon, France (PF, MJ, CC, PB, NS, and SR); the Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands (MMR); the Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark (A Tjønneland and AO); the Departments of Clinical Epidemiology (KO) and Surgical Gastroenterology (OT-U), Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark; INSERM, ERI 20, EA 4045, and Institut Gustave Roussy, Villejuif, France (FC-C, M-CB-R, and SM); the Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany (RK and JL); the Department of Epidemiology, German Institute of Human Nutrition, Potsdam-Rehbrücke, Germany (HB and UN); the Department of Hygiene and Epidemiology, University of Athens Medical School, Athens, Greece (A Trichopoulou, DT, and GM); the Molecular and Nutritional Epidemiology Unit, ISPO-Cancer Research and Prevention Institute, Florence, Italy (DP); the Nutritional Epidemiology Unit, National Cancer Institute, Milan, Italy (SS); the Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy (SP); the Cancer Registry, Azienda Ospedaliera “Civile MP Arezzo,” Ragusa, Italy (RT); the Department of Biomedical Sciences and Human Oncology, University of Torino, Torino, Italy (PV); the Division of Epidemiology, Public Health and Primary Care, Imperial College London, London, United Kingdom (PV, VG, TN, and ER); the Faculty of Medicine, Institute of Community Medicine, University of Tromsø, Tromsø, Norway (EL, DE, and GS); the Public Health Directorate, Asturias, Spain (LRS); the Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology, Barcelona, Spain (CAG); the Andalusian School of Public Health–Granada and CIBER Epidemiología y Salud Pública, Barcelona, Spain (M-JS); the Department of Public Health of Guipuzkoa, San Sebastian, Spain (MD); the Epidemiology Department, Murcia Health Council and CIBER Epidemiología y Salud Pública, Barcelona, Spain (CN); the Public Health Institute of Navarra, Pamplona, Spain (AB); the Departments of Clinical Sciences (GB) and Surgery (JM), Malmö University Hospital, Malmö, Sweden; the Departments of Public Health and Clinical Medicine (GH) and Medical Biosciences, Pathology (RP), Umeå University, Umeå, Sweden; the Medical Research Council Dunn Human Nutrition Unit, Cambridge, United Kingdom (SAB); the Clinical Gerontology, Department of Public Health and Primary Care, University of Cambridge, United Kingdom (K-TK); and the Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom (TJK and NEA).
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FJBvD and HBB-D-M contributed equally to this work as first authors.
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Supported by the European Commission: Public Health and Consumer Protection Directorate 1993-2004, Research Directorate-General 2005-, Ligue Contre le Cancer, Societé 3M, and Mutuelle Générale de l’Education Nationale, Institut National de la Santé et de la Recherche Médicale (France); German Cancer Aid, German Cancer Research Center, and Federal Ministry of Education and Research (Germany); Danish Cancer Society and the ISAFRUIT project funded by the European Commission under the Thematic Priority 5–Food Quality and Safety of the 6th Framework Programme of RTD (contract no. FP6-FOOD–CT-2006-016279) (Denmark); Health Research Fund of the Spanish Ministry of Health and the participating regional governments and institutions (Spain); Cancer Research UK, Medical Research Council, Stroke Association, British Heart Foundation, Department of Health, Food Standards Agency, and the Wellcome Trust (United Kingdom); Greek Ministry of Health, the Greek Ministry of Education and the Stavros Foundation (Greece); Italian Association for Research on Cancer, and the National Research Council (Italy); the Dutch Ministry of Public Health, Welfare and Sports, Dutch Ministry of Health, Dutch Prevention Funds, LK Research Funds, Dutch ZON (Zorg Ondk Nederland), and World Cancer Research Fund (Netherlands); Swedish Cancer Society, Swedish Scientific Council, and Regional Government of Skane (Sweden); and Norwegian Cancer Society (Norway).