Transcript Analysis of the Selenoproteome Indicates That Dietary Selenium Requirements of Rats Based on Selenium-Regulated Selenoprotein mRNA Levels Are Uniformly Less Than Those Based on Glutathione Peroxidase Activity123
Under an Elsevier user license
open archive
Abbreviations used:
Dio
iodothyronine deiodinase
Gpx1
glutathione peroxidase-1
Gpx3
plasma glutathione peroxidase
Gpx4
phospholipid hydroperoxide glutathione peroxidase
nt
nucleotide
Sephs2
selenophosphate synthetase-2
Selh
selenoprotein H
Sepw1
selenoprotein W
Sepp1
selenoprotein P
Sepx1
methionine-R-sulfoxide reductase
Txnrd
thioredoxin reductase
Cited by (0)
- 1
Supported in part by the NIH grant DK74184 and training grant T32-DK07665 (supporting K. M. B.) and by the University of Wisconsin Agricultural Experiment Station grant WIS04909.
- 2
Author disclosures: K. M. Barnes, J. K. Evenson, A. M. Raines, and R. A. Sunde, no conflicts of interest.
- 3
Supplemental Figure 1 and Supplemental Tables 1 5 are available with the online posting of this paper at jn.nutrition.org.
- 4
Present address: West Virginia University, G014 Agricultural Sciences Bldg., Morgantown, WV 26506.
Copyright © 2009 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.