J Korean Orthop Assoc. 2011 Oct;46(5):405-411. Korean.
Published online Oct 31, 2011.
Copyright © 2011 by The Korean Orthopaedic Association
Original Article

Total Knee Replacement Arthroplasty with NexGen®-LPS: Minimum 5 Year Follow-up Results

Kyoung Ho Moon, M.D., Ph.D., Dong Joo Lee, M.D., Ph.D., Joong Sun Lee, M.D. and Young Tae Kim, M.D.
    • Department of Orthopaedic Surgery, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
Received June 03, 2010; Accepted July 11, 2011.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

One hundred and thirty-six patients who underwent total knee replacement arthroplasty (TKRA) with NexGen®-LPS were analyzed for the clinical and radiologic results after a minimum follow-up of 5-years.

Materials and Methods

This study included 136 patients (209 knees) who underwent TKRA with NexGen®-LPS between August 1998 and February 2005 and had a minimum follow-up of 5 years. We evaluated the range of motion (ROM), American Knee Society knee functional scores, radiographic results and complication rates in the study subjects with an average 8.3 years of follow-up (range: 5-11.5 years). We also compared the results of the degenerative arthritis group (195 knees in 129 patients) with those of the rheumatoid arthritis group (14 knees in 7 patients).

Results

The mean ROM increased from 107.3° to 122° at the final follow-up. The flexion contracture also improved from 8.3° to 1.2° at final follow-up. The knee score improved from 51 to 94.7 at the final follow-up. The functional score improved from 38 to 84.2 (p<0.05) at final follow-up. There was no statistical significant difference in the results between the degenerative arthritis and rheumatoid arthritis groups (p>0.05). Valgus (α), varus (β), flexion (γ) and the posterior slope angle (δ) of the tibial components were well maintained both during the immediate postoperative period and at the final follow-up. There was no significant difference in the tibiofemoral angle and α, β, γ and δ angle (p>0.05) between the degenerative arthritis and rheumatoid arthritis groups. The alignment of the alternative substance was also relatively well maintained. Radiolucent lines were observed in 39 knees (18.7%), and in 42 zones out of 209 knees. The most common site of radiolucent lines was the medial side of the tibia in 21 knees. The overall incidence of radiolucent lines was 15% for the femur, 61% for the tibia and 24% for the patella. There was no statistically significant difference between the presence of radiolucent lines and the clinical results (p>0.05). There was 1 case of revision surgery due to loosening of implants at 8 years after surgery, but no early loosening was observed in the study subjects. Complications were found in 6 patients. Two patients with early postoperative infection were treated with revision surgery. Two patients with acute hematogenous infection 4 years after the initial operation were treated with revision surgery. Two patients with superficial infection were treated with antibiotics and regular dressing.

Conclusion

The patients treated with the NexGen®-LPS TKRA had a decreased level of postoperative pain and an improved knee joint ROM. A lower rate of complications was also found with this type of implant.

Keywords
NexGen®-LPS; total knee arthroplasty; osteoarthritis; rheumatoid arthritis

Figures

Figure 1
This diagram shows radiological evaluation and scoring system after TKRA.

Figure 2
Right anteroposterior knee radiograph shows radiolucent line (arrow).

Figure 3
(A) Right knee anteroposterior and lateral radiographs show a loose tibial implant with bone loss on the medial side of the tibia. (B) Radiographs after revision total knee arthroplasty.

Tables

Table 1
Comparative Clinical Results between the Osteoarthritis Group (OA) and the Rheumatoid Arthritis Group (RA)

Table 2
Radiologic Results according to Disease

Table 3
Results of Radiolucent Line Analysis according to Region

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