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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(04): 440-446
DOI: 10.4103/ijmpo.ijmpo_17_16
Original Article

Peripheral and Central Giant Cell Lesions in Children: Institutional Experience at Subharti Dental College and Hospital

Preetika Chandna
Department of Paedodontics and Preventive Dentistry, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India
,
Nikhil Srivastava
Department of Paedodontics and Preventive Dentistry, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India
,
Vishal Bansal
Department of Oral and Maxillofacial Surgery, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India
,
Vijay Wadhwan
Department of Oral and Maxillofacial Pathology and Microbiology, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India
,
Prajesh Dubey
Department of Oral and Maxillofacial Surgery, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Introduction: Giant cell lesions (GCG) are a group of varied lesions that contain a multitude of multinucleated, osteoclast like giant cells within connective tissue stroma. These include giant cell granulomas which may be central (CGCG), if they lie within the jaw bone, or, peripheral (PGCG) if they lie within the soft tissue. Giant cell granulomascomprised 9.29% of all oral lesions. This case seriescomprises of 5 giant cell lesions in children between the ages of 4 to 12 years. Materials and Methods: A retrospective analysis was conducted of all patients who were diagnosed with giant cell lesions and treated over a period of 10 years (from August 2004 to August 2014) at Subharti Dental College and Hospital, Meerut, India. Results: A total of 5 giant cell lesions were identified in this case series, of which 2 cases were diagnosed as PGCG and 3 cases as CGCG. Surgical excision and curettage was performed for 2 peripheral lesions under local anesthesia while 1 central lesion was excised under general anesthesia. Two central lesions were treated with a non-surgical approach using intralesional corticosteroid. Conclusion: Our experience suggests that a correct diagnosis andcomplete surgical excision with curettage is effective incomplete management of oral giant cell lesions in the pediatric age group.

Keywords

Central - giant cell granuloma - peripheral


Publication History

Article published online:
04 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used forcommercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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