CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2008; 18(04): 313-315
DOI: 10.4103/0971-3026.40958
Head & Neck Radiology

Right-sided hemiagenesis of the thyroid lobe and isthmus: A case report

Prabhat Kumar Tiwari
Department of Radiology, Manipal Teaching Hospital, PO Box: 341, Phulbari, Pokhara, Nepal
,
M Baxi
Department of Surgery, Manipal Teaching Hospital, PO Box: 341, Phulbari, Pokhara, Nepal
,
J Baxi
Department of Surgery, Manipal Teaching Hospital, PO Box: 341, Phulbari, Pokhara, Nepal
,
D Koirala
Department of Radiology, Manipal Teaching Hospital, PO Box: 341, Phulbari, Pokhara, Nepal
› Author Affiliations
Financial support and sponsorship Nil.

Abstract

Unilateral or bilateral hypoplasia or agenesis of one or both thyroid lobes, with or without isthmic agenesis, is a rare developmental anomaly. Hemiagenesis of the left lobe is far commoner than of the right. Clinically, these patients may be euthyroid, hyperthyroid, or hypothyroid. Ultrasonography is usually able to diagnose this condition easily, as we demonstrate in this case report of a 37-year-old lady with an incidentally detected thyroid nodule who was found to have hemiagenesis of the right lobe and isthmus.



Publication History

Article published online:
31 July 2021

© 2008. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 Aslaner A, Aydin M, Ozdere A. Multinodular goiter with thyroid hemiagenesis: A case report and review of the literature. Acta Chir Belg 2005;105:528-30.
  • 2 Karabay N, Comlekci A, Canda MS, Bayraktar F, Degirmenci B. Thyroid hemiagenesis with multinodular goiter: A case report and review of the literature. Endocr J 2003;50:409-13.
  • 3 Vαzquez-Chαvez C, Acevedo-Rivera K, Sartorius C, Espinosa-Said L. Thyroid hemiagenesis: Report of 3 cases and review of the literature. Gac Med Mex 1989;125:395-9.
  • 4 Veliz J, Pineda G. Thyroid hemiagenesis associated with Basedow-Graves disease: Report of a case. Rev Med Chil 2000;128:896-8.
  • 5 Sakurai K, Amano S, Enomoto K, Matsuo S, Kitajima A. Primary hyperparathyroidism with thyroid hemiagenesis. Asian J Surg 2007;30:151-3.
  • 6 Büyükdereli G, Guney IB, Kibar M, Kinaci C. Thyroid hemiagenesis: A report of three cases and review of the literature. Ann Nucl Med 2005;19:147-50.
  • 7 Huang SM, Chen HD, Wen TY, Kun MS. Right thyroid hemiagenesis associated with papillary thyroid cancer and an ectopic prelaryngeal thyroid: A case report. J Formos Med Assoc 2002;101:368-71.
  • 8 Mikosch P, Gallowitsch HJ, Kresnik E, Molnar M, Gomez I, Lind P. Thyroid hemiagenesis in an endemic goiter area diagnosed by ultrasonography: Report of sixteen patients. Thyroid 1999;9:1075-84.
  • 9 Khatri VP, Espinosa MH, Harada WA. Papillary adenocarcinoma in thyroid hemiagenesis. Head Neck 1992;14:312-5.
  • 10 Letonturier P, Hazard J, Tourneur R, Perlemuter L, Angel R. Thyroid hemiagenesis (single thyroid lobe): 8 cases. Nouv Presse Med 1979;8:1227-9.
  • 11 Shabana W, Delange F, Freson M, Osteaux M, De Schepper J. Prevalence of thyroid hemiagenesis: Ultrasound screening in normal children. Eur J Pediatr 2000;159:456-8.
  • 12 Castanet M, Leenhardt L, Lιger J, Simon-Carrι A, Lyonnet S, Pelet A, et al . Thyroid hemiagenesis is a rare variant of thyroid dysgenesis with a familial component but without Pax8 mutations in a cohort of 22 cases. Pediatr Res 2005;7:908-13.
  • 13 Gaudino R, Garel C, Czernichow P, Lιger J. Proportion of various types of thyroid disorders among newborns with congenital hypothyroidism and normally located gland: A regional cohort study. Clin Endocrinol (Oxf) 2005;62:444-8.
  • 14 Tonacchera M, Banco ME, Montanelli L, Di Cosmo C, Agretti P, De Marco G, et al . Genetic analysis of the PAX8 gene in children with congenital hypothyroidism and dysgenetic or eutopic thyroid glands: Identification of a novel sequence variant. Clin Endocrinol (Oxf) 2007;67:34-40.
  • 15 Rajmil HO, Rodriguez-Espinosa J, Soldevila J, Ordonez-Llanos J. Thyroid hemiagenesis in two sisters. J Endocrinol Invest 1984;7:393-4.
  • 16 Lee IT, Sheu WH, Lin SY. Familial form of thyroid dysgenesis: Report of thyroid hemiagenesis with accompanying Graves′ disease in a woman whose daughter has thyroid agenesis. Horm Res 2003;59:47-9.
  • 17 Baldini M, Orsatti A, Cantalamessa L. A singular case of Graves′ disease in congenital thyroid hemiagenesis. Horm Res 2005;63:107-10.
  • 18 Sasaki H, Futata T, Ninomiya H, Higashi Y, Okumura M. CT and MR imagings of single thyroid lobe (thyroid hemiagenesis) with Graves′ disease. Postgrad Med J 1991;67:701.
  • 19 Vaswani K, Vitellas KM, Bennett WF. Thyroid hemiagenesis with adenoma. AJR Am J Roentgenol 2000;175:895-8.
  • 20 Sharma R, Mondal A, Popli M, Sahoo M, Malhotra N, Soni S. Hemiagenesis of the thyroid associated with chronic lymphocytic thyroiditis. Clin Nucl Med 2001;26:506-8.
  • 21 Graber AL. Multinodular goiter in thyroid hemiagenesis. J Tenn Med Assoc 1983;76:174.
  • 22 Pizzini AM, Papi G, Corrado S, Carani C, Roti E. Thyroid hemiagenesis and incidentally discovered papillary thyroid cancer: Case report and review of the literature. J Endocrinol Invest 2005;28:66-71.
  • 23 Hydovitz JD, Winzelberg GA. Use of ultrasonography to eliminate hemiagenesis of a thyroid lobe in the differential diagnosis of a toxic adenoma (Plummer′s disease) Clin Nucl Med 1988;3:144-5.
  • 24 Leckie RG, Delaplain CB, Watabe JT, Darrow M. Thyroid hemiagenesis by I-123 thyroid scan with high-resolution real-time ultrasound confirmation Clin Nucl Med 1993;18:161-3.
  • 25 De Remigis P, D′Angelo M, Bonaduce S, Di Giandomenico V, Sensi S. Comparison of ultrasonic scanning and scintiscanning in the evaluation of thyroid hemiagenesis. J Clin Ultrasound 1985;13:561-3.
  • 26 Kreisner E, Camargo-Neto E, Maia CR, Gross JL. Accuracy of ultrasonography to establish the diagnosis and etiology of permanent primary congenital hypothyroidism. Clin Endocrinol (Oxf) 2003;59:361-5.