Incidence of chronic bronchitis: a prospective study in a large general population
A county in western Sweden.
To prospectively investigate the incidence rate of chronic bronchitis (CB) in relation to smoking, age, sex, atopy and asthma in a large sample of the general population.
Subjects from a county in western Sweden born between 1943 and 1973, who had participated in our previous study in 1993, were mailed a new questionnaire in 2003. Altogether 11 463 (72%) answered the questionnaire, which comprised items about smoking, atopy, respiratory symptoms and age at onset of CB symptoms. CB was defined as chronic productive cough for at least 3 months per year for 2 consecutive years.
There were 98 new cases of CB during 1993–2003 in the study population aged 30-60 years at follow-up. The incidence rate was 0.9/1000 person-years (py); there was no significant difference between women and men or different age groups. However, CB incidence was higher in women in relation to smoking (incidence rate ratio 3.6, 95%CI 1.9–7.3) and in those with ever asthma (hazard ratio 5.6, 95%CI 3.5–9.0).
This prospective general population-based study shows an incidence rate of CB of 0.9/1000 py. Smoking and asthma were both associated with an increased risk of CB.
Keywords: chronic bronchitis; epidemiology; general population; prospective
Document Type: Research Article
Affiliations: 1: Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden 2: Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden, Section of Occupational Medicine, Respiratory Diseases and Toxicology, University of Perugia, Perugia, Italy
Publication date: 01 July 2014
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