Late-Onset Pulmonary Fistula after Resection of Pulmonary Metastasis from Colorectal Cancer Following Perioperative Chemotherapy with Bevacizumab

Ryu Kanzaki; Yasushi Shintani; Masayoshi Inoue; Tomohiro Kawamura; Soichiro Funaki; Masato Minami; Meinoshin Okumura

doi:10.5761/atcs.cr.16-00117

Case Reports

Late-Onset Pulmonary Fistula after Resection of Pulmonary Metastasis from Colorectal Cancer Following Perioperative Chemotherapy with Bevacizumab

Ryu Kanzaki, Yasushi Shintani, Masayoshi Inoue, Tomohiro Kawamura, Soichiro Funaki, Masato Minami, Meinoshin Okumura

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Keywords: colorectal cancer, pulmonary metastasectomy, pulmonary fistula, bevacizumab

JOURNAL FREE ACCESS

2017 Volume 23 Issue 3 Pages 149-152

DOI https://doi.org/10.5761/atcs.cr.16-00117

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Abstract

Chemotherapy with bevacizumab followed by surgery is now a viable treatment option for pulmonary metastasis from colorectal cancer (CRC). We herein report two cases of late-onset pulmonary fistula after resection of pulmonary metastasis from CRC following perioperative chemotherapy with bevacizumab. One patient suffered from a late-onset pulmonary fistula that occurred 3 months after pulmonary resection, which was treated with chest drainage and pleurodesis. The other patient suffered from a pulmonary fistula after three cycles of chemotherapy with bevacizumab after pulmonary resection, and underwent surgery to treat the fistula.

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