Dermoscopic findings in an early malignant fibrous histiocytoma on the face
Keywords:
dermoscopy, skin cancerAbstract
Malignant fibrous histiocytoma (MFH), currently classified as undifferentiated pleomorphic sarcoma, is the most frequent soft tissue sarcoma in adulthood, but it is not as common as a primary skin tumor. MFH affects mostly the thighs and trunk, head and neck is an infrequent presentation in adults. MFH is often diagnosed in advanced stages, with a tendency to local recurrence and systemic metastasis. Since tumor thickness and size are identified as major prognostic factors, early recognition becomes crucial to improve prognosis. We present a case of a cutaneous malignant fibrous histiocytoma located on the face in which dermoscopy was useful in clinical management and definition.
References
Weiss SW, Enzinger FM. Malignant fibrous histiocytoma: an analysis of 200 cases. Cancer.1978;41:2250-2266. PubMed
Gibbs J, Huang P, Lee R, McGrath B, et al. Malignant fibrous histiocytoma: an institutional review. Cancer Invest. 2001;19:23-27. PubMed
Sureda N, Bosch M, Valente E, Kurpis M, Ruiz A. Malignant fibrohistiocytoma: cephalic location as infrequent presentation. Arch Argent Dermatol. 2008;58:55-59.
Zalaudek I, Kreusch J, Giacomel J, Ferrara G, Catricalà C, Argenziano G. How to diagnose nonpigmented skin tumors: a review of vascular structures seen with dermoscopy: part II. Nonmelanocytic skin tumors. J Am Acad Dermatol. 2010;63(3):377-386. PubMed CrossRef
Cuellar F, Vilalta A, Puig S, Palou J, Salerni G, Malvehy J. New dermoscopic pattern in actinic keratosis and related conditions. Arch Dermatol. 2009;145(6):732. PubMed CrossRef
O’Brien JE, Stout AP. Malignant fibrous xanthomas. Cancer. 1964;17:1445-1455. PubMed
Weiss SW, Goldblum JR. Malignant fibrohistiocytic tumors. In: Gibson LE, ed. Enzinger and Weiss’s Soft Tissue Tumors. 4th ed. St. Louis: CV Mosby; 2001:535–569.
Pezzi CM, Rawlings MS, Esgro JJ, Pollock RE, Romsdahl MM. Prognostic factors in 227 patients with malignant fibrous histiocytoma. Cancer. 1992;69:2098-2103. PubMed
Published
Issue
Section
License
Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.