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CC BY-NC-ND 4.0 · Sleep Sci 2022; 15(S 02): 369-374
DOI: 10.5935/1984-0063.20210019
ORIGINAL ARTICLES

Possible influences of vitamin D levels on sleep quality, depression, anxiety and physiological stress in patients with chronic obstructive pulmonary disease: a case control study

Carlos José Dias
1   Universidade Federal do Maranhão, Departamento de Educação Física - São Luís - MA - Brazil.
,
Rodrigo Barroso
1   Universidade Federal do Maranhão, Departamento de Educação Física - São Luís - MA - Brazil.
,
Carlos Alberto Alves Dias-Filho
1   Universidade Federal do Maranhão, Departamento de Educação Física - São Luís - MA - Brazil.
,
Andressa Coelho Ferreira
1   Universidade Federal do Maranhão, Departamento de Educação Física - São Luís - MA - Brazil.
,
Christian Emmanuel Torres Cabido
1   Universidade Federal do Maranhão, Departamento de Educação Física - São Luís - MA - Brazil.
,
Carlos C Crestani
2   Universidade Estadual de São Paulo, Departamento de Farmácia - Araraquara - São Paulo - Brazil.
,
Mayra Santos Silva
3   Universidade Federal de São Paulo, Departamento de Psicobiologia - São Paulo - São Paulo - Brazil.
,
Alcimar Nunes Pinheiro
4   Universidade Federal do Maranhão, Departamento de Medicina - São Luís -MA - Brazil.
,
Bruno Rodrigues
5   Universidade Estadual de Campinas, Departamento de Educação física -Campinas - São Paulo - Brazil.
,
Cristiano Teixeira Mostarda
1   Universidade Federal do Maranhão, Departamento de Educação Física - São Luís - MA - Brazil.
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ABSTRACT

This study aimed to evaluate the effect of vitamin D deficiency on sleep quality, depression, anxiety, and physiological stress in patients with chronic obstructive pulmonary disease (COPD). We screened for COPD patients with normal (NorVD) (n=24) and insufficient (InsVD) (n=7) vitamin D levels. The Pittsburgh sleep quality index (PSQI), the Beck anxiety inventory (BAI), the Beck depression inventory (BDI) and the Baevsky’s stress index were used for the sleep and psychometric evaluation. The evaluation of sleep quality by PSQI showed that NorVD individuals had higher duration and quality of sleep when compared with the InsVD group. Additionally, the group InsVD presented higher risk of developing sleep quality (OR=6.20; 95% CI=1.334, 29.013; p=0.009). BDI was higher in the InsVD, and this group had a higher risk of developing moderate and severe depression (OR=3.37; 95% CI=0.895, 12.722; p=0.03). The stress index indicated higher values in the InsVD in relation to the NorVD group (InsVD=24±0.8 vs. NorVD=16±0.9), and the group InsVD showed higher risk of developing high and very high physiological stress (OR=7.70; 95% CI=1.351, 43.878; p=0.01). The stress and sleep quality effects were negatively correlated with vitamin D levels. Insufficient levels of vitamin D negatively affect sleep quality and psychometric variables.

Keywords:

Anxiety - Depression - Sleep Quality - COPD - Vitamin D - Stress


Publication History

Article published online:
01 December 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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