Elsevier

Clinical Medicine

Volume 20, Issue 6, November 2020, Pages 565-567
Clinical Medicine

CME: Rheumatology
Rheumatoid arthritis and bone health

https://doi.org/10.7861/clinmed.20.6.rabhGet rights and content
Under a Creative Commons license
open access

ABSTRACT

Rheumatoid arthritis (RA) is an inflammatory arthropathy affecting 1% of the population, with a female predominance. Systemic inflammation is a key component of RA disease; corticosteroids are often required to rapidly control disease activity. Both inflammation and corticosteroids, however, have an adverse effect on bone mineral density, potentially resulting in osteoporosis and an increased risk of fractures. In this article, we describe the link between RA and impaired bone health, together with appropriate strategies to maintain bone density and reduce fracture risk. Key approaches include achieving adequate control of inflammation, minimising corticosteroid use, monitoring bone mineral density and intervening with antiosteoporosis medications when indicated.

KEYWORDS:

Rheumatoid arthritis
osteoporosis
epidemiology
fracture
glucocorticoid

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