Case Reports
Holmes Tremor Partially Responsive to Topiramate: A Case Report
Authors:
- Natalia González Rojas
- Martin Cesarini
- José Luis Etcheverry
- Gustavo Da Prat
- Tomás Viera Aramburu
- Emilia Mabel GattoEmail Emilia Mabel Gatto
Abstract
Background: Holmes tremor is a rare symptomatic movement disorder, characterized by a combination of resting, postural, and intention tremor. It is usually caused by lesions in the brainstem, thalamus, and cerebellum. Despite pharmacological advances, its treatment remains a challenge; many medications have been used with various degrees of effectiveness. Stereotactic thalamotomy and deep brain stimulation in the ventralis intermedius nucleus have been effective surgical procedures in cases refractory to medical treatment.
Case Report: Here we report a young woman with topiramate-responsive Holmes tremor secondary to a brainstem cavernoma.
Discussion: Herein we report a Holmes tremor responsive to Topiramate.
Keywords:
- Year: 2018
- Volume: 8
- Page/Article: 565
- DOI: 10.5334/tohm.416
- Submitted on 9 Apr 2018
- Accepted on 31 May 2018
- Published on 26 Jun 2018
- Peer Reviewed