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Current Pain and Headache Reports

Erschienen in:

01.09.2019 | Secondary Headache (M Robbins, Section Editor)

Linking Traumatic Brain Injury, Sleep Disruption and Post-Traumatic Headache: a Potential Role for Glymphatic Pathway Dysfunction

verfasst von: Juan Piantino, Miranda M. Lim, Craig D. Newgard, Jeffrey Iliff

Erschienen in: Current Pain and Headache Reports | Ausgabe 9/2019

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Abstract

Purpose of the Review

Traumatic brain injury (TBI) is a major public health concern in the USA and worldwide. Sleep disruption and headaches are two of the most common problems reported by patients after TBI. In this manuscript, we review the current knowledge regarding the relation between post-traumatic sleep disruption and headaches. We also describe the role of the glymphatic system as a potential link between TBI, sleep, and headaches.

Recent Findings

Recent studies show a reciprocal relation between post-traumatic sleep disruption and headaches: patients with sleep disruption after TBI report more headaches, and post-traumatic headaches are a risk factor for developing disrupted sleep. Despite this clinical association, the exact mechanisms linking post-traumatic sleep disruption and headaches are not well understood. The glymphatic pathway, a newly described brain–wide network of perivascular spaces that supports the clearance of interstitial solutes and wastes from the brain, is active primarily during sleep, and becomes dysfunctional after TBI. We propose a model where changes in glymphatic function caused by TBI and post-traumatic sleep disruption may impair the clearance of neuropeptides involved in the pathogenesis of post-traumatic headaches, such as CGRP.

Summary

The relation between TBI, post-traumatic sleep disruption, and post-traumatic headaches, although well documented in the literature, remains poorly understood. Dysfunction of the glymphatic system caused by TBI offers a novel and exiting explanation to this clinically observed phenomenon. The proposed model, although theoretical, could provide important mechanistic insights to the TBI-sleep-headache association.

Faul M XL, Wald MM, Coronado V. Traumatic brain injury in the United States. In: Centers for Disease Control and Prevention NCfIPaC, editor. Atlanta, GA2010.

VA/DoD. Clinical practice guideline for management of concussion/mild traumatic brain injury. J Rehabil Res Dev. 2009;46(6):Cp1–68.

Taylor CA, Bell JM, Breiding MJ, Xu L. Traumatic brain injury-related emergency department visits, hospitalizations, and deaths - United States, 2007 and 2013. Morbidity and mortality weekly report Surveillance summaries (Washington, DC : 2002). 2017;66(9):1–16. https://doi.org/10.15585/mmwr.ss6609a1.CrossRef

Centers for Disease control and Prevention.What are the signs and symptoms of concussion. http://www.cdc.gov/traumaticbraininjury/symptoms.html. Accessed February 25th 2019.

Mathias JL, Alvaro PK. Prevalence of sleep disturbances, disorders, and problems following traumatic brain injury: a meta-analysis. Sleep Med. 2012;13(7):898–905. https://doi.org/10.1016/j.sleep.2012.04.006.CrossRefPubMed

Lew HL, Lin PH, Fuh JL, Wang SJ, Clark DJ, Walker WC. Characteristics and treatment of headache after traumatic brain injury: a focused review. Am J Phys Med Rehabil. 2006;85(7):619–27. https://doi.org/10.1097/01.phm.0000223235.09931.c0.CrossRefPubMed

Lucas S, Hoffman JM, Bell KR, Dikmen S. A prospective study of prevalence and characterization of headache following mild traumatic brain injury. Cephalalgia. 2014;34(2):93–102. https://doi.org/10.1177/0333102413499645.CrossRefPubMed

Kostyun RO, Milewski MD, Hafeez I. Sleep disturbance and neurocognitive function during the recovery from a sport-related concussion in adolescents. Am J Sports Med. 2015;43(3):633–40. https://doi.org/10.1177/0363546514560727.CrossRefPubMed

Murdaugh DL, Ono KE, Reisner A, Burns TG. Assessment of sleep quantity and sleep disturbances during recovery from sports-related concussion in youth athletes. Arch Phys Med Rehabil. 2018;99(5):960–6. https://doi.org/10.1016/j.apmr.2018.01.005.CrossRefPubMed

10.

•• Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Sci Transl Med. 2012;4(147):147ra11. https://doi.org/10.1126/scitranslmed.3003748 First description of the role of the paravascular spaces in clearence of amyloid beta. CrossRef

11.

•• Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M et al First publication describing the increase in convective exchange of cerebrospinal fluid and interstitial fluid that occurs during sleep et al.. Science. 2013;342(6156):373–377. doi:https://doi.org/10.1126/science.1241224 Sleep drives metabolite clearance from the adult brain

12.

• Iliff JJ, Chen MJ, Plog BA, Zeppenfeld DM, Soltero M, Yang L, et al. Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. J Neurosci. 2014;34(49):16180–93. https://doi.org/10.1523/jneurosci.3020-14.2014 Important paper showing how traumatic brian injury impairs glimphatic function and promotes accumulation of tau. CrossRefPubMedPubMedCentral

13.

Schatz P, Moser RS, Covassin T, Karpf R. Early indicators of enduring symptoms in high school athletes with multiple previous concussions. Neurosurgery. 2011;68(6):1562–7; discussion 7. https://doi.org/10.1227/NEU.0b013e31820e382e.CrossRefPubMed

14.

Blinman TA, Houseknecht E, Snyder C, Wiebe DJ, Nance ML. Postconcussive symptoms in hospitalized pediatric patients after mild traumatic brain injury. J Pediatr Surg. 2009;44(6):1223–8. https://doi.org/10.1016/j.jpedsurg.2009.02.027.CrossRefPubMed

15.

Watson NF, Dikmen S, Machamer J, Doherty M, Temkin N. Hypersomnia following traumatic brain injury. J Clin Sleep Med. 2007;3(4):363–8.PubMedPubMedCentral

16.

• Wickwire EM, Williams SG, Roth T, Capaldi VF, Jaffe M, Moline M, et al. Sleep, sleep disorders, and mild traumatic brain injury. What we know and what we need to know: findings from a National Working Group. Neurotherapeutics. 2016;13(2):403–17. https://doi.org/10.1007/s13311-016-0429-3 A very good review on the current understanding of the relation between TBI and sleep disturbances. CrossRefPubMedPubMedCentral

17.

Ouellet MC, Beaulieu-Bonneau S, Morin CM. Insomnia in patients with traumatic brain injury: frequency, characteristics, and risk factors. J Head Trauma Rehabil. 2006;21(3):199–212.CrossRef

18.

Collen J, Orr N, Lettieri CJ, Carter K, Holley AB. Sleep disturbances among soldiers with combat-related traumatic brain injury. Chest. 2012;142(3):622–30. https://doi.org/10.1378/chest.11-1603.CrossRefPubMed

19.

Clinchot DM, Bogner J, Mysiw WJ, Fugate L, Corrigan J. Defining sleep disturbance after brain injury. Am J Phys Med Rehabil. 1998;77(4):291–5.CrossRef

20.

Baumann CR, Bassetti CL, Valko PO, Haybaeck J, Keller M, Clark E, et al. Loss of hypocretin (orexin) neurons with traumatic brain injury. Ann Neurol. 2009;66(4):555–9. https://doi.org/10.1002/ana.21836.CrossRefPubMedPubMedCentral

21.

Verma A, Anand V, Verma NP. Sleep disorders in chronic traumatic brain injury. J Clin Sleep Med. 2007;3(4):357–62.PubMedPubMedCentral

22.

Kempf J, Werth E, Kaiser PR, Bassetti CL, Baumann CR. Sleep-wake disturbances 3 years after traumatic brain injury. J Neurol Neurosurg Psychiatry. 2010;81(12):1402–5. https://doi.org/10.1136/jnnp.2009.201913.CrossRefPubMed

23.

Castriotta RJ, Wilde MC, Lai JM, Atanasov S, Masel BE, Kuna ST. Prevalence and consequences of sleep disorders in traumatic brain injury. J Clin Sleep Med. 2007;3(4):349–56.PubMedPubMedCentral

24.

Baumann CR, Werth E, Stocker R, Ludwig S, Bassetti CL. Sleep-wake disturbances 6 months after traumatic brain injury: a prospective study. Brain. 2007;130(Pt 7):1873–83. https://doi.org/10.1093/brain/awm109.CrossRefPubMed

25.

Masel BE, Scheibel RS, Kimbark T, Kuna ST. Excessive daytime sleepiness in adults with brain injuries. Arch Phys Med Rehabil. 2001;82(11):1526–32. https://doi.org/10.1053/apmr.2001.26093.CrossRefPubMed

26.

Wilde MC, Castriotta RJ, Lai JM, Atanasov S, Masel BE, Kuna ST. Cognitive impairment in patients with traumatic brain injury and obstructive sleep apnea. Arch Phys Med Rehabil. 2007;88(10):1284–8. https://doi.org/10.1016/j.apmr.2007.07.012.CrossRefPubMed

27.

Parcell DL, Ponsford JL, Redman JR, Rajaratnam SM. Poor sleep quality and changes in objectively recorded sleep after traumatic brain injury: a preliminary study. Arch Phys Med Rehabil. 2008;89(5):843–50. https://doi.org/10.1016/j.apmr.2007.09.057.CrossRefPubMed

28.

Shekleton JA, Parcell DL, Redman JR, Phipps-Nelson J, Ponsford JL, Rajaratnam SM. Sleep disturbance and melatonin levels following traumatic brain injury. Neurology. 2010;74(21):1732–8. https://doi.org/10.1212/WNL.0b013e3181e0438b.CrossRefPubMedPubMedCentral

29.

Sandsmark DK, Elliott JE, Lim MM. Sleep-wake disturbances after traumatic brain injury: synthesis of human and animal studies. Sleep. 2017;40(5). https://doi.org/10.1093/sleep/zsx044.

30.

Valko PO, Gavrilov YV, Yamamoto M, Finn K, Reddy H, Haybaeck J, et al. Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury. Ann Neurol. 2015;77(1):177–82. https://doi.org/10.1002/ana.24298.CrossRefPubMed

31.

Baumann CR, Stocker R, Imhof HG, Trentz O, Hersberger M, Mignot E, et al. Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury. Neurology. 2005;65(1):147–9. https://doi.org/10.1212/01.wnl.0000167605.02541.f2.CrossRefPubMed

32.

Rye DB, Bliwise DL, Parker K, Trotti LM, Saini P, Fairley J, et al. Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors. Sci Transl Med. 2012;4(161):161ra51. https://doi.org/10.1126/scitranslmed.3004685.CrossRef

33.

Junger EC, Newell DW, Grant GA, Avellino AM, Ghatan S, Douville CM, et al. Cerebral autoregulation following minor head injury. J Neurosurg. 1997;86(3):425–32. https://doi.org/10.3171/jns.1997.86.3.0425.CrossRefPubMed

34.

Kumar A, Loane DJ. Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. Brain Behav Immun. 2012;26(8):1191–201. https://doi.org/10.1016/j.bbi.2012.06.008.CrossRefPubMed

35.

Paparrigopoulos T, Melissaki A, Tsekou H, Efthymiou A, Kribeni G, Baziotis N, et al. Melatonin secretion after head injury: a pilot study. Brain Inj. 2006;20(8):873–8. https://doi.org/10.1080/02699050600832114.CrossRefPubMed

36.

Seifman MA, Gomes K, Nguyen PN, Bailey M, Rosenfeld JV, Cooper DJ, et al. Measurement of serum melatonin in intensive care unit patients: changes in traumatic brain injury, trauma, and medical conditions. Front Neurol. 2014;5:237. https://doi.org/10.3389/fneur.2014.00237.CrossRefPubMedPubMedCentral

37.

Tan G, Fink B, Dao TK, Hebert R, Farmer LS, Sanders A, et al. Associations among pain, PTSD, mTBI, and heart rate variability in veterans of Operation Enduring and Iraqi Freedom: a pilot study. Pain Med (Malden, Mass). 2009;10(7):1237–45. https://doi.org/10.1111/j.1526-4637.2009.00712.x.CrossRef

38.

Morin CM, Colecchi C, Stone J, Sood R, Brink D. Behavioral and pharmacological therapies for late-life insomnia: a randomized controlled trial. Jama. 1999;281(11):991–9.CrossRef

39.

Jacobs GD, Pace-Schott EF, Stickgold R, Otto MW. Cognitive behavior therapy and pharmacotherapy for insomnia: a randomized controlled trial and direct comparison. Arch Intern Med. 2004;164(17):1888–96. https://doi.org/10.1001/archinte.164.17.1888.CrossRefPubMed

40.

Sivertsen B, Omvik S, Pallesen S, Bjorvatn B, Havik OE, Kvale G, et al. Cognitive behavioral therapy vs zopiclone for treatment of chronic primary insomnia in older adults: a randomized controlled trial. Jama. 2006;295(24):2851–8. https://doi.org/10.1001/jama.295.24.2851.CrossRefPubMed

41.

Morin CM, Vallieres A, Guay B, Ivers H, Savard J, Merette C, et al. Cognitive behavioral therapy, singly and combined with medication, for persistent insomnia: a randomized controlled trial. Jama. 2009;301(19):2005–15. https://doi.org/10.1001/jama.2009.682.CrossRefPubMedPubMedCentral

42.

Kaiser PR, Valko PO, Werth E, Thomann J, Meier J, Stocker R, et al. Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury. Neurology. 2010;75(20):1780–5. https://doi.org/10.1212/WNL.0b013e3181fd62a2.CrossRefPubMed

43.

Menn SJ, Yang R, Lankford A. Armodafinil for the treatment of excessive sleepiness associated with mild or moderate closed traumatic brain injury: a 12-week, randomized, double-blind study followed by a 12-month open-label extension. J Clin Sleep Med. 2014;10(11):1181–91. https://doi.org/10.5664/jcsm.4196.CrossRefPubMedPubMedCentral

44.

Ponsford JL, Ziino C, Parcell DL, Shekleton JA, Roper M, Redman JR, et al. Fatigue and sleep disturbance following traumatic brain injury--their nature, causes, and potential treatments. J Head Trauma Rehabil. 2012;27(3):224–33. https://doi.org/10.1097/HTR.0b013e31824ee1a8.CrossRefPubMed

45.

Blume HK, Vavilala MS, Jaffe KM, Koepsell TD, Wang J, Temkin N, et al. Headache after pediatric traumatic brain injury: a cohort study. Pediatrics. 2012;129(1):e31–9. https://doi.org/10.1542/peds.2011-1742.CrossRefPubMed

46.

Nampiaparampil DE. Prevalence of chronic pain after traumatic brain injury: a systematic review. Jama. 2008;300(6):711–9. https://doi.org/10.1001/jama.300.6.711.CrossRefPubMed

47.

Sufrinko A, McAllister-Deitrick J, Elbin RJ, Collins MW, Kontos AP. Family history of migraine associated with posttraumatic migraine symptoms following sport-related concussion. J Head Trauma Rehabil. 2018;33(1):7–14. https://doi.org/10.1097/htr.0000000000000315.CrossRefPubMedPubMedCentral

48.

Kjeldgaard D, Forchhammer H, Teasdale T, Jensen RH. Chronic post-traumatic headache after mild head injury: a descriptive study. Cephalalgia. 2014;34(3):191–200. https://doi.org/10.1177/0333102413505236.CrossRefPubMed

49.

Wang SJ, Fuh JL, Lu SR, Juang KD. Outcomes and predictors of chronic daily headache in adolescents: a 2-year longitudinal study. Neurology. 2007;68(8):591–6. https://doi.org/10.1212/01.wnl.0000252800.82704.62.CrossRefPubMed

50.

Headache classification Committee of the International Headache Society (IHS) the international classification of headache disorders, 3rd edition. Cephalalgia : an international journal of headache. 2018;38(1):1–211. https://doi.org/10.1177/0333102417738202.

51.

Lucas S, Hoffman JM, Bell KR, Walker W, Dikmen S. Characterization of headache after traumatic brain injury. Cephalalgia. 2012;32(8):600–6. https://doi.org/10.1177/0333102412445224.CrossRefPubMed

52.

Lambru G, Matharu M. Traumatic head injury in cluster headache: cause or effect? Curr Pain Headache Rep. 2012;16(2):162–9. https://doi.org/10.1007/s11916-012-0248-0.CrossRefPubMed

53.

Kuczynski A, Crawford S, Bodell L, Dewey D, Barlow KM. Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort. Dev Med Child Neurol. 2013;55(7):636–41. https://doi.org/10.1111/dmcn.12152.CrossRefPubMed

54.

Seifert TD, Evans RW. Posttraumatic headache: a review. Curr Pain Headache Rep. 2010;14(4):292–8. https://doi.org/10.1007/s11916-010-0117-7.CrossRefPubMed

55.

Giza CC, Hovda DA. The new neurometabolic cascade of concussion. Neurosurgery. 2014;75(Suppl 4):S24–33. https://doi.org/10.1227/neu.0000000000000505.CrossRefPubMedPubMedCentral

56.

Barkhoudarian G, Hovda DA, Giza CC. The molecular pathophysiology of concussive brain injury - an update. Phys Med Rehabil Clin N Am. 2016;27(2):373–93. https://doi.org/10.1016/j.pmr.2016.01.003.CrossRefPubMed

57.

Stephens JA, Liu P, Lu H, Suskauer SJ. Cerebral blood flow after mild traumatic brain injury: associations between symptoms and post-injury perfusion. J Neurotrauma. 2018;35(2):241–8. https://doi.org/10.1089/neu.2017.5237.CrossRefPubMedPubMedCentral

58.

Kamins J, Bigler E, Covassin T, Henry L, Kemp S, Leddy JJ, et al. What is the physiological time to recovery after concussion? A systematic review. Br J Sports Med. 2017;51(12):935–40. https://doi.org/10.1136/bjsports-2016-097464.CrossRefPubMed

59.

Zeng Z, Li Y, Lu S, Huang W, Di W. Efficacy of CoQ10 as supplementation for migraine: a meta-analysis. Acta Neurol Scand. 2019;139(3):284–93. https://doi.org/10.1111/ane.13051.CrossRefPubMed

60.

Zielman R, Wijnen JP, Webb A, Onderwater GLJ, Ronen I, Ferrari MD, et al. Cortical glutamate in migraine. Brain. 2017;140(7):1859–71. https://doi.org/10.1093/brain/awx130.CrossRefPubMed

61.

Powers SW, Coffey CS, Chamberlin LA, Ecklund DJ, Klingner EA, Yankey JW, et al. Trial of amitriptyline, topiramate, and placebo for pediatric migraine. N Engl J Med. 2017;376(2):115–24. https://doi.org/10.1056/NEJMoa1610384.CrossRefPubMed

62.

Noruzzadeh R, Modabbernia A, Aghamollaii V, Ghaffarpour M, Harirchian MH, Salahi S, et al. Memantine for prophylactic treatment of migraine without aura: a randomized double-blind placebo-controlled study. Headache. 2016;56(1):95–103. https://doi.org/10.1111/head.12732.CrossRef

63.

Mei Z, Qiu J, Alcon S, Hashim J, Rotenberg A, Sun Y, et al. Memantine improves outcomes after repetitive traumatic brain injury. Behav Brain Res. 2018;340:195–204. https://doi.org/10.1016/j.bbr.2017.04.017.CrossRefPubMed

64.

Schock SC, Munyao N, Yakubchyk Y, Sabourin LA, Hakim AM, Ventureyra EC, et al. Cortical spreading depression releases ATP into the extracellular space and purinergic receptor activation contributes to the induction of ischemic tolerance. Brain Res. 2007;1168:129–38. https://doi.org/10.1016/j.brainres.2007.06.070.CrossRefPubMed

65.

Burnstock G, Krugel U, Abbracchio MP, Illes P. Purinergic signalling: from normal behaviour to pathological brain function. Prog Neurobiol. 2011;95(2):229–74. https://doi.org/10.1016/j.pneurobio.2011.08.006.CrossRefPubMed

66.

Jackson EK, Boison D, Schwarzschild MA, Kochanek PM. Purines: forgotten mediators in traumatic brain injury. J Neurochem. 2016;137(2):142–53. https://doi.org/10.1111/jnc.13551.CrossRefPubMedPubMedCentral

67.

Ning YL, Yang N, Chen X, Xiong RP, Zhang XZ, Li P, et al. Adenosine A2A receptor deficiency alleviates blast-induced cognitive dysfunction. J Cereb Blood Flow Metab. 2013;33(11):1789–98. https://doi.org/10.1038/jcbfm.2013.127.CrossRefPubMedPubMedCentral

68.

Lipton RB, Diener HC, Robbins MS, Garas SY, Patel K. Caffeine in the management of patients with headache. J Headache Pain. 2017;18(1):107. https://doi.org/10.1186/s10194-017-0806-2.CrossRefPubMedPubMedCentral

69.

Edvinsson L. The Trigeminovascular pathway: role of CGRP and CGRP receptors in migraine. Headache. 2017;57(Suppl 2):47–55. https://doi.org/10.1111/head.13081.CrossRefPubMed

70.

Bree D, Levy D. Development of CGRP-dependent pain and headache related behaviours in a rat model of concussion: implications for mechanisms of post-traumatic headache. Cephalalgia. 2018;38(2):246–58. https://doi.org/10.1177/0333102416681571.CrossRefPubMed

71.

Daiutolo BV, Tyburski A, Clark SW, Elliott MB. Trigeminal pain molecules, allodynia, and photosensitivity are pharmacologically and genetically modulated in a model of traumatic brain injury. J Neurotrauma. 2016;33(8):748–60. https://doi.org/10.1089/neu.2015.4087.CrossRefPubMedPubMedCentral

72.

Elliott MB, Oshinsky ML, Amenta PS, Awe OO, Jallo JI. Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury. Headache. 2012;52(6):966–84. https://doi.org/10.1111/j.1526-4610.2012.02160.x.CrossRefPubMedPubMedCentral

73.

Tyburski AL, Cheng L, Assari S, Darvish K, Elliott MB. Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system. J Headache Pain. 2017;18(1):16. https://doi.org/10.1186/s10194-017-0726-1.CrossRefPubMedPubMedCentral

74.

Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurol. 2018;17(2):174–82. https://doi.org/10.1016/s1474-4422(17)30435-0.CrossRefPubMed

75.

Zagami AS, Edvinsson L, Goadsby PJ. Pituitary adenylate cyclase activating polypeptide and migraine. Ann Clin Transl Neurol. 2014;1(12):1036–40. https://doi.org/10.1002/acn3.113.CrossRefPubMedPubMedCentral

76.

Vink R, Gabrielian L, Thornton E. The role of substance P in secondary pathophysiology after traumatic brain injury. Front Neurol. 2017;8:304. https://doi.org/10.3389/fneur.2017.00304.CrossRefPubMedPubMedCentral

77.

May A, Goadsby PJ. Substance P receptor antagonists in the therapy of migraine. Expert Opin Investig Drugs. 2001;10(4):673–8. https://doi.org/10.1517/13543784.10.4.673.CrossRefPubMed

78.

Lumba-Brown A, Harley J, Lucio S, Vaida F, Hilfiker M. Hypertonic saline as a therapy for pediatric concussive pain: a randomized controlled trial of symptom treatment in the emergency department. Pediatr Emerg Care. 2014;30(3):139–45. https://doi.org/10.1097/pec.0000000000000084.CrossRefPubMedPubMedCentral

79.

Mittenberg W, Canyock EM, Condit D, Patton C. Treatment of post-concussion syndrome following mild head injury. J Clin Exp Neuropsychol. 2001;23(6):829–36. https://doi.org/10.1076/jcen.23.6.829.1022.CrossRefPubMed

80.

Blume HK. Posttraumatic headache in pediatrics: an update and review. Curr Opin Pediatr. 2018;30(6):755–63. https://doi.org/10.1097/mop.0000000000000691.CrossRefPubMed

81.

Gawel MJ, Rothbart P, Jacobs H. Subcutaneous sumatriptan in the treatment of acute episodes of posttraumatic headache. Headache. 1993;33(2):96–7.CrossRef

82.

Erickson JC. Treatment outcomes of chronic post-traumatic headaches after mild head trauma in US soldiers: an observational study. Headache. 2011;51(6):932–44. https://doi.org/10.1111/j.1526-4610.2011.01909.x.CrossRefPubMed

83.

Kamins J, Charles A. Posttraumatic headache: basic mechanisms and therapeutic targets. Headache. 2018;58(6):811–26. https://doi.org/10.1111/head.13312.CrossRefPubMed

84.

Abu-Arefeh I, Russell G. Prevalence of headache and migraine in schoolchildren. Bmj. 1994;309(6957):765–9.CrossRef

85.

Owens JA, Witmans M. Sleep problems. Curr Probl Pediatr Adolesc Health Care. 2004;34(4):154–79. https://doi.org/10.1016/j.cppeds.2003.10.003.CrossRefPubMed

86.

Wang J, Huang Q, Li N, Tan G, Chen L, Zhou J. Triggers of migraine and tension-type headache in China: a clinic-based survey. Eur J Neurol. 2013;20(4):689–96. https://doi.org/10.1111/ene.12039.CrossRefPubMed

87.

Barbanti P, Fabbrini G, Aurilia C, Vanacore N, Cruccu G. A case-control study on excessive daytime sleepiness in episodic migraine. Cephalalgia. 2007;27(10):1115–9. https://doi.org/10.1111/j.1468-2982.2007.01399.x.CrossRefPubMed

88.

Boardman HF, Thomas E, Millson DS, Croft PR. Psychological, sleep, lifestyle, and comorbid associations with headache. Headache. 2005;45(6):657–69. https://doi.org/10.1111/j.1526-4610.2005.05133.x.CrossRefPubMed

89.

Bruni O, Fabrizi P, Ottaviano S, Cortesi F, Giannotti F, Guidetti V. Prevalence of sleep disorders in childhood and adolescence with headache: a case-control study. Cephalalgia. 1997;17(4):492–8. https://doi.org/10.1046/j.1468-2982.1997.1704492.x.CrossRefPubMed

90.

Miller VA, Palermo TM, Powers SW, Scher MS, Hershey AD. Migraine headaches and sleep disturbances in children. Headache. 2003;43(4):362–8.CrossRef

91.

Barabas G, Ferrari M, Matthews WS. Childhood migraine and somnambulism. Neurology. 1983;33(7):948–9.CrossRef

92.

Pradalier A, Giroud M, Dry J. Somnambulism, migraine and propranolol. Headache. 1987;27(3):143–5.CrossRef

93.

Dexter JD. The relationship between stage III + IV + REM sleep and arousals with migraine. Headache. 1979;19(7):364–9.CrossRef

94.

Tkachenko N, Singh K, Hasanaj L, Serrano L, Kothare SV. Sleep disorders associated with mild traumatic brain injury using sport concussion assessment tool 3. Pediatr Neurol. 2016;57:46–50.e1. https://doi.org/10.1016/j.pediatrneurol.2015.12.019.CrossRefPubMed

95.

Jaramillo CA, Eapen BC, McGeary CA, McGeary DD, Robinson J, Amuan M, et al. A cohort study examining headaches among veterans of Iraq and Afghanistan wars: associations with traumatic brain injury, PTSD, and depression. Headache. 2016;56(3):528–39. https://doi.org/10.1111/head.12726.CrossRefPubMed

96.

Hou L, Han X, Sheng P, Tong W, Li Z, Xu D, et al. Risk factors associated with sleep disturbance following traumatic brain injury: clinical findings and questionnaire based study. PLoS One. 2013;8(10):e76087. https://doi.org/10.1371/journal.pone.0076087.CrossRefPubMedPubMedCentral

97.

Singh NN, Sahota P. Sleep-related headache and its management. Curr Treat Options Neurol. 2013;15(6):704–22. https://doi.org/10.1007/s11940-013-0258-1.CrossRefPubMed

98.

Kelman L, Rains JC. Headache and sleep: examination of sleep patterns and complaints in a large clinical sample of migraineurs. Headache. 2005;45(7):904–10. https://doi.org/10.1111/j.1526-4610.2005.05159.x.CrossRefPubMed

99.

Uhlig BL, Engstrom M, Odegard SS, Hagen KK, Sand T. Headache and insomnia in population-based epidemiological studies. Cephalalgia. 2014;34(10):745–51. https://doi.org/10.1177/0333102414540058.CrossRefPubMed

100.

Tran DP, Spierings EL. Headache and insomnia: their relation reviewed. Cranio. 2013;31(3):165–70. https://doi.org/10.1179/crn.2013.026.CrossRefPubMed

101.

Fialho LM, Pinho RS, Lin J, Minett TS, Vitalle MS, Fisberg M, et al. Sleep terrors antecedent is common in adolescents with migraine. Arq Neuropsiquiatr. 2013;71(2):83–6.CrossRef

102.

Freedom T. Headaches and sleep disorders. Disease-a-month : DM. 2015;61(6):240–8. https://doi.org/10.1016/j.disamonth.2015.03.008.CrossRefPubMed

103.

Chiu YC, Hu HY, Lee FP, Huang HM. Tension-type headache associated with obstructive sleep apnea: a nationwide population-based study. J Headache Pain. 2015;16:34. https://doi.org/10.1186/s10194-015-0517-5.CrossRefPubMedPubMedCentral

104.

Schurks M, Winter A, Berger K, Kurth T. Migraine and restless legs syndrome: a systematic review. Cephalalgia. 2014;34(10):777–94. https://doi.org/10.1177/0333102414537725.CrossRefPubMed

105.

Esposito M, Parisi P, Miano S, Carotenuto M. Migraine and periodic limb movement disorders in sleep in children: a preliminary case-control study. J Headache Pain. 2013;14:57. https://doi.org/10.1186/1129-2377-14-57.CrossRefPubMedPubMedCentral

106.

Dahmen N, Kasten M, Wieczorek S, Gencik M, Epplen JT, Ullrich B. Increased frequency of migraine in narcoleptic patients: a confirmatory study. Cephalalgia. 2003;23(1):14–9. https://doi.org/10.1046/j.1468-2982.2003.00343.x.CrossRefPubMed

107.

Harnod T, Wang YC, Kao CH. Higher risk of developing a subsequent migraine in adults with nonapnea sleep disorders: a nationwide population-based cohort study. Eur J Intern Med. 2015;26(4):232–6. https://doi.org/10.1016/j.ejim.2015.03.002.CrossRefPubMed

108.

Lateef T, Swanson S, Cui L, Nelson K, Nakamura E, Merikangas K. Headaches and sleep problems among adults in the United States: findings from the National Comorbidity Survey-Replication study. Cephalalgia. 2011;31(6):648–53. https://doi.org/10.1177/0333102410390395.CrossRefPubMed

109.

Dosi C, Riccioni A, Della Corte M, Novelli L, Ferri R, Bruni O. Comorbidities of sleep disorders in childhood and adolescence: focus on migraine. Nat Sci Sleep. 2013;5:77–85. https://doi.org/10.2147/nss.s34840.CrossRefPubMedPubMedCentral

110.

Dash MB, Douglas CL, Vyazovskiy VV, Cirelli C, Tononi G. Long-term homeostasis of extracellular glutamate in the rat cerebral cortex across sleep and waking states. J Neurosci. 2009;29(3):620–9. https://doi.org/10.1523/JNEUROSCI.5486-08.2009.CrossRefPubMedPubMedCentral

111.

Kong J, Shepel PN, Holden CP, Mackiewicz M, Pack AI, Geiger JD. Brain glycogen decreases with increased periods of wakefulness: implications for homeostatic drive to sleep. J Neurosci. 2002;22(13):5581–7.CrossRef

112.

Franken P, Dijk DJ, Tobler I, Borbely AA. Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature. Am J Phys. 1991;261(1 Pt 2):R198–208. https://doi.org/10.1152/ajpregu.1991.261.1.R198.CrossRef

113.

Shearer WT, Reuben JM, Mullington JM, Price NJ, Lee BN, Smith EO, et al. Soluble TNF-alpha receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight. J Allergy Clin Immunol. 2001;107(1):165–70. https://doi.org/10.1067/mai.2001.112270.CrossRefPubMed

114.

Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Follett H, Kales A, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab. 2004;89(5):2119–26. https://doi.org/10.1210/jc.2003-031562.CrossRefPubMed

115.

Dodick DW, Eross EJ, Parish JM, Silber M. Clinical, anatomical, and physiologic relationship between sleep and headache. Headache. 2003;43(3):282–92.CrossRef

116.

Lovati C, D’Amico D, Raimondi E, Mariani C, Bertora P. Sleep and headache: a bidirectional relationship. Expert Rev Neurother. 2010;10(1):105–17. https://doi.org/10.1586/ern.09.135.CrossRefPubMed

117.

Zawilska JB, Skene DJ, Arendt J. Physiology and pharmacology of melatonin in relation to biological rhythms. Pharmacol Rep. 2009;61(3):383–410.CrossRef

118.

Kunz D, Mahlberg R. A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder. J Sleep Res. 2010;19(4):591–6. https://doi.org/10.1111/j.1365-2869.2010.00848.x.CrossRefPubMed

119.

Nesbitt AD, Leschziner GD, Peatfield RC. Headache, drugs and sleep. Cephalalgia. 2014;34(10):756–66. https://doi.org/10.1177/0333102414542662. CrossRefPubMed

120.

Supornsilpchai W, Sanguanrangsirikul S, Maneesri S, Srikiatkhachorn A. Serotonin depletion, cortical spreading depression, and trigeminal nociception. Headache. 2006;46(1):34–9. https://doi.org/10.1111/j.1526-4610.2006.00310.x.CrossRefPubMed

121.

Garcia-Azorin D, Santos-Lasaosa S, Gago-Veiga AB, Viguera Romero J, Guerrero-Peral AL. Real world preventative drug management of migraine among Spanish neurologists. J Headache Pain. 2019;20(1):19. https://doi.org/10.1186/s10194-019-0971-6.CrossRefPubMed

122.

Simon MJ, Iliff JJ. Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease. Biochim Biophys Acta. 2016;1862(3):442–51. https://doi.org/10.1016/j.bbadis.2015.10.014.CrossRefPubMed

123.

Iliff JJ, Lee H, Yu M, Feng T, Logan J, Nedergaard M, et al. Brain-wide pathway for waste clearance captured by contrast-enhanced MRI. J Clin Invest. 2013;123(3):1299–309. https://doi.org/10.1172/jci67677.CrossRefPubMedPubMedCentral

124.

Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523(7560):337–41. https://doi.org/10.1038/nature14432.CrossRefPubMedPubMedCentral

125.

Aspelund A, Antila S, Proulx ST, Karlsen TV, Karaman S, Detmar M, et al. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J Exp Med. 2015;212(7):991–9. https://doi.org/10.1084/jem.20142290.CrossRefPubMedPubMedCentral

126.

Iliff JJ, Wang M, Zeppenfeld DM, Venkataraman A, Plog BA, Liao Y, et al. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain. J Neurosci. 2013;33(46):18190–9. https://doi.org/10.1523/jneurosci.1592-13.2013.CrossRefPubMedPubMedCentral

127.

Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, et al. Aquaporin-4-dependent glymphatic solute transport in the rodent brain. eLife. 2018;7. https://doi.org/10.7554/eLife.40070.

128.

Ringstad G, Vatnehol SAS, Eide PK. Glymphatic MRI in idiopathic normal pressure hydrocephalus. Brain. 2017;140(10):2691–705. https://doi.org/10.1093/brain/awx191.CrossRefPubMedPubMedCentral

129.

Ringstad G, Valnes LM, Dale AM, Pripp AH, Vatnehol SS, Emblem KE, et al. Brain-wide glymphatic enhancement and clearance in humans assessed with MRI. JCI Insight. 2018;3(13). https://doi.org/10.1172/jci.insight.121537.

130.

Goodman JR, Adham ZO, Woltjer RL, Lund AW, Iliff JJ. Characterization of dural sinus-associated lymphatic vasculature in human Alzheimer’s dementia subjects. Brain Behav Immun. 2018;73:34–40. https://doi.org/10.1016/j.bbi.2018.07.020.CrossRefPubMed

131.

Absinta M, Ha SK, Nair G, Sati P, Luciano NJ, Palisoc M, et al. Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI. eLife. 2017;6. https://doi.org/10.7554/eLife.29738.

132.

Eide PK, Vatnehol SAS, Emblem KE, Ringstad G. Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes. Sci Rep. 2018;8(1):7194. https://doi.org/10.1038/s41598-018-25666-4.CrossRefPubMedPubMedCentral

133.

Plog BA, Dashnaw ML, Hitomi E, Peng W, Liao Y, Lou N, et al. Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system. J Neurosci. 2015;35(2):518–26. https://doi.org/10.1523/JNEUROSCI.3742-14.2015.CrossRefPubMedPubMedCentral

134.

Gaberel T, Gakuba C, Goulay R, Martinez De Lizarrondo S, Hanouz JL, Emery E, et al. Impaired glymphatic perfusion after strokes revealed by contrast-enhanced MRI: a new target for fibrinolysis? Stroke. 2014;45(10):3092–6. https://doi.org/10.1161/strokeaha.114.006617.CrossRefPubMed

135.

Bolay H, Reuter U, Dunn AK, Huang Z, Boas DA, Moskowitz MA. Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med. 2002;8(2):136–42. https://doi.org/10.1038/nm0202-136.CrossRefPubMed

136.

Schain AJ, Melo-Carrillo A, Strassman AM, Burstein R. Cortical spreading depression closes paravascular space and impairs glymphatic flow: implications for migraine headache. J Neurosci. 2017;37(11):2904–15. https://doi.org/10.1523/JNEUROSCI.3390-16.2017.CrossRefPubMedPubMedCentral

137.

Yuan H, Lauritsen CG, Kaiser EA, Silberstein SD. CGRP Monoclonal antibodies for migraine: rationale and Progress. BioDrugs. 2017;31(6):487–501. https://doi.org/10.1007/s40259-017-0250-5. CrossRefPubMed

138.

Messlinger K, Hanesch U, Baumgartel M, Trost B, Schmidt RF. Innervation of the dura mater encephali of cat and rat: ultrastructure and calcitonin gene-related peptide-like and substance P-like immunoreactivity. Anat Embryol. 1993;188(3):219–37.CrossRef

139.

Edvinsson L, Ekman R, Jansen I, McCulloch J, Uddman R. Calcitonin gene-related peptide and cerebral blood vessels: distribution and vasomotor effects. J Cereb Blood Flow Metab. 1987;7(6):720–8. https://doi.org/10.1038/jcbfm.1987.126.CrossRefPubMed

140.

Eftekhari S, Salvatore CA, Calamari A, Kane SA, Tajti J, Edvinsson L. Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion. Neuroscience. 2010;169(2):683–96. https://doi.org/10.1016/j.neuroscience.2010.05.016.CrossRefPubMed

141.

Lennerz JK, Ruhle V, Ceppa EP, Neuhuber WL, Bunnett NW, Grady EF, et al. Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: differences between peripheral and central CGRP receptor distribution. J Comp Neurol. 2008;507(3):1277–99. https://doi.org/10.1002/cne.21607.CrossRefPubMed

142.

Messlinger K. The big CGRP flood - sources, sinks and signalling sites in the trigeminovascular system. J Headache Pain. 2018;19(1):22. https://doi.org/10.1186/s10194-018-0848-0.CrossRefPubMedPubMedCentral

143.

Eftekhari S, Salvatore CA, Johansson S, Chen TB, Zeng Z, Edvinsson L. Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood-brain barrier. Brain Res. 2015;1600:93–109. https://doi.org/10.1016/j.brainres.2014.11.031.CrossRefPubMed

144.

Dux M, Will C, Eberhardt M, Fischer MJM, Messlinger K. Stimulation of rat cranial dura mater with potassium chloride causes CGRP release into the cerebrospinal fluid and increases medullary blood flow. Neuropeptides. 2017;64:61–8. https://doi.org/10.1016/j.npep.2017.02.080.CrossRefPubMed

145.

Bouley J, Chung DY, Ayata C, Brown RH Jr, Henninger N. Cortical spreading depression denotes concussion injury. J Neurotrauma. 2018;36:1008–17. https://doi.org/10.1089/neu.2018.5844.CrossRefPubMed

Titel: Linking Traumatic Brain Injury, Sleep Disruption and Post-Traumatic Headache: a Potential Role for Glymphatic Pathway Dysfunction
verfasst von: Juan Piantino
Miranda M. Lim
Craig D. Newgard
Jeffrey Iliff
Publikationsdatum: 01.09.2019
Verlag: Springer US
Erschienen in: Current Pain and Headache Reports / Ausgabe 9/2019
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI: https://doi.org/10.1007/s11916-019-0799-4

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Linking Traumatic Brain Injury, Sleep Disruption and Post-Traumatic Headache: a Potential Role for Glymphatic Pathway Dysfunction

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Springer Medizin

Abstract

Purpose of the Review

Recent Findings

Summary

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