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Erschienen in: Medical Oncology 1/2008

01.03.2008 | Original Paper

Liver embolizations in oncology: A review

Part I. Arterial (chemo)embolizations

verfasst von: Peter Gunvén

Erschienen in: Medical Oncology | Ausgabe 1/2008

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Abstract

Arterial embolization of the liver often temporarily retards the growth of liver tumors which are mainly nourished arterially. The use of degradable agents avoids collateral formation which would prohibit repeat procedures and permit tumor regrowth. The effect of embolizations is largest in small hypervascular lesions, e.g., many hepatocellular or neuroendocrine cancers. Toxic chemicals can be added, chemoembolization, with unproven effects on responses and survival rates. Institutional differences in indications and procedures make evaluation of embolizations difficult. However, intermediate-term survival increases in selected cases of unresectable hepatocellular cancers and hormonal symptoms from neuroendocrine tumors often improve. Scant experience supports embolization for anti-tumoral effects in some pediatric tumors, to control bleeding from ruptured tumors, for symptomatic hemangiomas, and for downstaging of hepatocellular cancers before transplantation.
Literatur
1.
Zurück zum Zitat Wallace S, et al. Hepatic artery infusion and chemoembolization in the management of liver metastases. Cardiovasc Intervent Radiol 1990;13:153–60.PubMed Wallace S, et al. Hepatic artery infusion and chemoembolization in the management of liver metastases. Cardiovasc Intervent Radiol 1990;13:153–60.PubMed
2.
Zurück zum Zitat Belghiti J, et al. Continuous versus intermittent portal triad clamping for liver resection: a controlled study. Ann Surg 1999;229:369–75.PubMed Belghiti J, et al. Continuous versus intermittent portal triad clamping for liver resection: a controlled study. Ann Surg 1999;229:369–75.PubMed
3.
Zurück zum Zitat Hiatt JR, Gabbay J, Busuttil RW. Surgical anatomy of the hepatic arteries in 1000 cases. Ann Surg 1994;220:50–2.PubMed Hiatt JR, Gabbay J, Busuttil RW. Surgical anatomy of the hepatic arteries in 1000 cases. Ann Surg 1994;220:50–2.PubMed
4.
Zurück zum Zitat Ngan H, Peh WC. Arteriovenous shunting in hepatocellular carcinoma: its prevalence and clinical significance. Clin Radiol 1997;52:36–40.PubMed Ngan H, Peh WC. Arteriovenous shunting in hepatocellular carcinoma: its prevalence and clinical significance. Clin Radiol 1997;52:36–40.PubMed
5.
Zurück zum Zitat Walser RH, et al. Diagnostic angioscintigraphic evaluation of malignant hepatic tumors before catheter embolization: determination of shunt, flow distribution, and reflux. Cardiovasc Intervent Radiol 1996;19:77–81.PubMed Walser RH, et al. Diagnostic angioscintigraphic evaluation of malignant hepatic tumors before catheter embolization: determination of shunt, flow distribution, and reflux. Cardiovasc Intervent Radiol 1996;19:77–81.PubMed
6.
Zurück zum Zitat Chung JW, Park JH, Im JG, Han JK, Han MC. Pulmonary oil embolism after transcatheter oily chemoembolization of hepatocellular carcinoma. Radiology 1993;187:689–93.PubMed Chung JW, Park JH, Im JG, Han JK, Han MC. Pulmonary oil embolism after transcatheter oily chemoembolization of hepatocellular carcinoma. Radiology 1993;187:689–93.PubMed
7.
Zurück zum Zitat Sakamoto I, et al. Complications associated with transcatheter arterial embolization for hepatic tumors. Radiographics 1998;18:605–19.PubMed Sakamoto I, et al. Complications associated with transcatheter arterial embolization for hepatic tumors. Radiographics 1998;18:605–19.PubMed
8.
Zurück zum Zitat Yoo KM, Yoo BG, Kim KS, Lee SU, Han BH. Cerebral lipiodol embolism during transcatheter arterial chemoembolization. Neurology 2004;63:181–3.PubMed Yoo KM, Yoo BG, Kim KS, Lee SU, Han BH. Cerebral lipiodol embolism during transcatheter arterial chemoembolization. Neurology 2004;63:181–3.PubMed
9.
Zurück zum Zitat Huang MS, et al. Comparison of long-term effects between intra-arterially delivered ethanol and Gelfoam for the treatment of severe arterioportal shunt in patients with hepatocellular carcinoma. World J Gastroenterol 2004;10:825–9.PubMed Huang MS, et al. Comparison of long-term effects between intra-arterially delivered ethanol and Gelfoam for the treatment of severe arterioportal shunt in patients with hepatocellular carcinoma. World J Gastroenterol 2004;10:825–9.PubMed
10.
Zurück zum Zitat Shimamura Y, Gunven P, Ishii M, Abe K. Temporary redistribution of hepatic or pancreatic blood flow by vascular occluders during intra-arterial chemotherapy for carcinoma of the liver or pancreas. Surg Gynecol Obstet 1993;177:617–9.PubMed Shimamura Y, Gunven P, Ishii M, Abe K. Temporary redistribution of hepatic or pancreatic blood flow by vascular occluders during intra-arterial chemotherapy for carcinoma of the liver or pancreas. Surg Gynecol Obstet 1993;177:617–9.PubMed
11.
Zurück zum Zitat Gates J, Hartnell GG, Stuart KE, Clouse ME. Chemoembolization of hepatic neoplasms: safety, complications, and when to worry. Radiographics 1999;19:399–414.PubMed Gates J, Hartnell GG, Stuart KE, Clouse ME. Chemoembolization of hepatic neoplasms: safety, complications, and when to worry. Radiographics 1999;19:399–414.PubMed
12.
Zurück zum Zitat Brown DB, et al. Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy. J Vasc Interv Radiol 2006;17(2 Pt 1):225–32.PubMedCrossRef Brown DB, et al. Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy. J Vasc Interv Radiol 2006;17(2 Pt 1):225–32.PubMedCrossRef
13.
Zurück zum Zitat Shimamura Y, et al. Combined peripheral and central chemoembolization of liver tumors. Experience with lipiodol-doxorubicin and gelatin sponge (L-TAE). Cancer 1988;61:238–42.PubMed Shimamura Y, et al. Combined peripheral and central chemoembolization of liver tumors. Experience with lipiodol-doxorubicin and gelatin sponge (L-TAE). Cancer 1988;61:238–42.PubMed
14.
Zurück zum Zitat De Maio E, et al. Transcatheter arterial procedures in the treatment of patients with hepatocellular carcinoma: a review of literature. Crit Rev Oncol Hematol 2003;46:285–95.PubMed De Maio E, et al. Transcatheter arterial procedures in the treatment of patients with hepatocellular carcinoma: a review of literature. Crit Rev Oncol Hematol 2003;46:285–95.PubMed
15.
Zurück zum Zitat Llovet JM, et al. (Barcelona Liver Cancer Group). Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet 2002;359(9319):1734–39.PubMed Llovet JM, et al. (Barcelona Liver Cancer Group). Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet 2002;359(9319):1734–39.PubMed
16.
Zurück zum Zitat Pelletier G, et al. Treatment of unresectable hepatocellular carcinoma with lipiodol chemoembolization: a multicenter randomized trial. Groupe CHCJ Hepatol 1998;29:129–34. Pelletier G, et al. Treatment of unresectable hepatocellular carcinoma with lipiodol chemoembolization: a multicenter randomized trial. Groupe CHCJ Hepatol 1998;29:129–34.
17.
Zurück zum Zitat Lo CM, et al. Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology 2002;35:1164–71.PubMed Lo CM, et al. Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology 2002;35:1164–71.PubMed
18.
Zurück zum Zitat Madden MV, et al. Randomised trial of targeted chemotherapy with lipiodol and 5-epidoxorubicin compared with symptomatic treatment for hepatoma. Gut 1993;34:1598–600.PubMed Madden MV, et al. Randomised trial of targeted chemotherapy with lipiodol and 5-epidoxorubicin compared with symptomatic treatment for hepatoma. Gut 1993;34:1598–600.PubMed
19.
Zurück zum Zitat Bruix J, et al. Transarterial embolization versus symptomatic treatment in patients with advanced hepatocellular carcinoma: results of a randomized, controlled trial in a single institution. Hepatology 1998;27:1578–83.PubMed Bruix J, et al. Transarterial embolization versus symptomatic treatment in patients with advanced hepatocellular carcinoma: results of a randomized, controlled trial in a single institution. Hepatology 1998;27:1578–83.PubMed
20.
Zurück zum Zitat Latoo MY, Oliver A, Roebuck D. Anaesthetic management of hepatic artery chemoembolization in a paediatric patient. Paediatr Anaesth 2002;12:629–31.PubMed Latoo MY, Oliver A, Roebuck D. Anaesthetic management of hepatic artery chemoembolization in a paediatric patient. Paediatr Anaesth 2002;12:629–31.PubMed
21.
Zurück zum Zitat Park JW. Risk of hepatitis B exacerbation is low after transcatheter arterial chemoembolization therapy for patients with HBV-related hepatocellular carcinoma: report of a prospective study. Am J Gastroenterol 2005;100:2194–200.PubMed Park JW. Risk of hepatitis B exacerbation is low after transcatheter arterial chemoembolization therapy for patients with HBV-related hepatocellular carcinoma: report of a prospective study. Am J Gastroenterol 2005;100:2194–200.PubMed
22.
Zurück zum Zitat Jang JW. A randomized controlled study of preemptive lamivudine in patients receiving transarterial chemo-lipiodolization. Hepatology 2006 Feb;43(2):233–40. Jang JW. A randomized controlled study of preemptive lamivudine in patients receiving transarterial chemo-lipiodolization. Hepatology 2006 Feb;43(2):233–40.
23.
Zurück zum Zitat Chen MS, et al. High-dose iodized oil transcatheter arterial chemoembolization for patients with large hepatocellular carcinoma. World J Gastroenterol 2002;8:74–8.PubMed Chen MS, et al. High-dose iodized oil transcatheter arterial chemoembolization for patients with large hepatocellular carcinoma. World J Gastroenterol 2002;8:74–8.PubMed
24.
Zurück zum Zitat Cheng HY, et al. Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT. World J Gastroenterol 2004;10:2753–55.PubMed Cheng HY, et al. Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT. World J Gastroenterol 2004;10:2753–55.PubMed
25.
Zurück zum Zitat Raoul JL, et al. Chemoembolization of hepatocellular carcinomas. A study of the biodistribution and pharmacokinetics of doxorubicin. Cancer 1992;70:585–90.PubMed Raoul JL, et al. Chemoembolization of hepatocellular carcinomas. A study of the biodistribution and pharmacokinetics of doxorubicin. Cancer 1992;70:585–90.PubMed
26.
Zurück zum Zitat Llovet JM, Bruix J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. Hepatology 2003;47:479–47. Llovet JM, Bruix J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. Hepatology 2003;47:479–47.
27.
Zurück zum Zitat Camma C, et al. Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trials. Radiology 2002;224:47–54.PubMed Camma C, et al. Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trials. Radiology 2002;224:47–54.PubMed
28.
Zurück zum Zitat Lu W, Li Y, He X, Chen Y. Transcatheter arterial chemoembolization for hepatocellular carcinoma in patients with cirrhosis: evaluation of two kinds of dosages of anticancer drugs and analysis of prognostic factors. Hepatogastroenterology 2003;50:2079–83.PubMed Lu W, Li Y, He X, Chen Y. Transcatheter arterial chemoembolization for hepatocellular carcinoma in patients with cirrhosis: evaluation of two kinds of dosages of anticancer drugs and analysis of prognostic factors. Hepatogastroenterology 2003;50:2079–83.PubMed
29.
Zurück zum Zitat Castells A, et al. Transarterial embolization for hepatocellular carcinoma. Antibiotic prophylaxis and clinical meaning of postembolization fever. J Hepatol 1995;22:460–5. Castells A, et al. Transarterial embolization for hepatocellular carcinoma. Antibiotic prophylaxis and clinical meaning of postembolization fever. J Hepatol 1995;22:460–5.
30.
Zurück zum Zitat Kaibori M, et al. Preoperative chemolipiodolization of the whole liver for hepatocellular carcinoma. Anticancer Res 2004;24(3b):1929–33.PubMed Kaibori M, et al. Preoperative chemolipiodolization of the whole liver for hepatocellular carcinoma. Anticancer Res 2004;24(3b):1929–33.PubMed
31.
Zurück zum Zitat Hatanaka Y, et al. Unresectable hepatocellular carcinoma: analysis of prognostic factors in transcatheter management. Radiology 1995;195:747–52.PubMed Hatanaka Y, et al. Unresectable hepatocellular carcinoma: analysis of prognostic factors in transcatheter management. Radiology 1995;195:747–52.PubMed
32.
Zurück zum Zitat Lu CD, Qi YG, Peng SY. Lipiodolization with or without gelatin sponge in hepatic arterial chemoembolization for hepatocellular carcinoma. Chin Med J (Engl) 1994;107:209–15. Lu CD, Qi YG, Peng SY. Lipiodolization with or without gelatin sponge in hepatic arterial chemoembolization for hepatocellular carcinoma. Chin Med J (Engl) 1994;107:209–15.
33.
Zurück zum Zitat Wigmore SJ, et al. Postchemoembolisation syndrome–tumour necrosis or hepatocyte injury? Br J Cancer 2003;89:1473–77. Wigmore SJ, et al. Postchemoembolisation syndrome–tumour necrosis or hepatocyte injury? Br J Cancer 2003;89:1473–77.
34.
Zurück zum Zitat Song SY, et al. Liver abscess after transcatheter oily chemoembolization for hepatic tumors: incidence, predisposing factors, and clinical outcome. J Vasc Interv Radiol 2001;12:313–320.PubMed Song SY, et al. Liver abscess after transcatheter oily chemoembolization for hepatic tumors: incidence, predisposing factors, and clinical outcome. J Vasc Interv Radiol 2001;12:313–320.PubMed
35.
Zurück zum Zitat X-ray contrast media. Pharmacology, clinic. (Review in Swedish.) The Swedish Board of Health and Welfare, Drug Information 1976;3:1 p. 53–9 (Socialstyrelsens läkemedelsinformation. Röntgenkontrastmedel. Farmakologi, klinik. 1976 3:1, p. 53–59). X-ray contrast media. Pharmacology, clinic. (Review in Swedish.) The Swedish Board of Health and Welfare, Drug Information 1976;3:1 p. 53–9 (Socialstyrelsens läkemedelsinformation. Röntgenkontrastmedel. Farmakologi, klinik. 1976 3:1, p. 53–59).
36.
Zurück zum Zitat Nakamura H, et al. Outcome of localized hepatocellular carcinoma treated with segmental arterioportal chemoembolization. Cancer Chemother Pharmacol 1992;31 Suppl:S69–S71.PubMed Nakamura H, et al. Outcome of localized hepatocellular carcinoma treated with segmental arterioportal chemoembolization. Cancer Chemother Pharmacol 1992;31 Suppl:S69–S71.PubMed
37.
Zurück zum Zitat Huo TI, Wu JC, Lee PC, Chang FY, Lee SD. Incidence and risk factors for acute renal failure in patients with hepatocellular carcinoma undergoing transarterial chemoembolization: a prospective study. Liver Int 2004;24:210–5.PubMed Huo TI, Wu JC, Lee PC, Chang FY, Lee SD. Incidence and risk factors for acute renal failure in patients with hepatocellular carcinoma undergoing transarterial chemoembolization: a prospective study. Liver Int 2004;24:210–5.PubMed
38.
Zurück zum Zitat Brown DB. Society of Interventional Radiology position statement on chemoembolization of hepatic malignancies. J Vasc Interv Radiol 2006;17(2 Pt 1):217–23.PubMed Brown DB. Society of Interventional Radiology position statement on chemoembolization of hepatic malignancies. J Vasc Interv Radiol 2006;17(2 Pt 1):217–23.PubMed
39.
Zurück zum Zitat Ryu M, et al. Therapeutic results of resection, transcatheter arterial embolization and percutaneous transhepatic ethanol injection in 3225 patients with hepatocellular carcinoma: a retrospective multicenter study. Jpn J Clin Oncol 1997;27:251–7.PubMed Ryu M, et al. Therapeutic results of resection, transcatheter arterial embolization and percutaneous transhepatic ethanol injection in 3225 patients with hepatocellular carcinoma: a retrospective multicenter study. Jpn J Clin Oncol 1997;27:251–7.PubMed
40.
Zurück zum Zitat Takayasu K, et al. Comparison of CT findings with resected specimens after chemoembolization with iodized oil for hepatocellular carcinoma. AJR Am J Roentgenol 2000;175:699–704.PubMed Takayasu K, et al. Comparison of CT findings with resected specimens after chemoembolization with iodized oil for hepatocellular carcinoma. AJR Am J Roentgenol 2000;175:699–704.PubMed
41.
Zurück zum Zitat Yamasaki S, et al. A prospective randomized trial of the preventive effect of pre-operative transcatheter arterial embolization against recurrence of hepatocellular carcinoma. Jpn J Cancer Res 1996;87:206–11.PubMed Yamasaki S, et al. A prospective randomized trial of the preventive effect of pre-operative transcatheter arterial embolization against recurrence of hepatocellular carcinoma. Jpn J Cancer Res 1996;87:206–11.PubMed
42.
Zurück zum Zitat Schwartz JD, Schwartz M, Mandeli J, Sung M. Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: review of the randomised clinical trials. Lancet Oncol 2002;3:593–603.PubMed Schwartz JD, Schwartz M, Mandeli J, Sung M. Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: review of the randomised clinical trials. Lancet Oncol 2002;3:593–603.PubMed
43.
Zurück zum Zitat Chan ES, Chow PK, Tai B, Machin D, Soo K. Neoadjuvant and adjuvant therapy for operable hepatocellular carcinoma. Cochrane Database Syst Rev 2000;(2):CD001199. Chan ES, Chow PK, Tai B, Machin D, Soo K. Neoadjuvant and adjuvant therapy for operable hepatocellular carcinoma. Cochrane Database Syst Rev 2000;(2):CD001199.
44.
Zurück zum Zitat Wu CC, et al. Preoperative transcatheter arterial chemoembolization for resectable large hepatocellular carcinoma: a reappraisal. Br J Surg 1995;82:122–6.PubMed Wu CC, et al. Preoperative transcatheter arterial chemoembolization for resectable large hepatocellular carcinoma: a reappraisal. Br J Surg 1995;82:122–6.PubMed
45.
Zurück zum Zitat Bhattacharya S, et al. Small hepatocellular carcinomas in cirrhotic explant livers: identification by macroscopic examination and lipiodol localization. Hepatology 1997;25:613–8.PubMed Bhattacharya S, et al. Small hepatocellular carcinomas in cirrhotic explant livers: identification by macroscopic examination and lipiodol localization. Hepatology 1997;25:613–8.PubMed
46.
Zurück zum Zitat Kwok PC, et al. Randomized controlled trial to compare the dose of adjuvant chemotherapy after curative resection of hepatocellular carcinoma. J Gastroenterol Hepatol 2003;18:450–5.PubMed Kwok PC, et al. Randomized controlled trial to compare the dose of adjuvant chemotherapy after curative resection of hepatocellular carcinoma. J Gastroenterol Hepatol 2003;18:450–5.PubMed
47.
Zurück zum Zitat Shimamura Y, Gunven P, Ishii M, Ono M, Abe K. Debulking surgery and arterial embolization for unresectable liver cancer. Hepatogastroenterology 1993;40:10–3.PubMed Shimamura Y, Gunven P, Ishii M, Ono M, Abe K. Debulking surgery and arterial embolization for unresectable liver cancer. Hepatogastroenterology 1993;40:10–3.PubMed
48.
Zurück zum Zitat Inoue K, et al. Volume reduction surgery for advanced hepatocellular carcinoma. J Cancer Res Clin Oncol 2004;130:362–6. Epub 2004 Mar 18.PubMed Inoue K, et al. Volume reduction surgery for advanced hepatocellular carcinoma. J Cancer Res Clin Oncol 2004;130:362–6. Epub 2004 Mar 18.PubMed
49.
Zurück zum Zitat Wakabayashi H, et al. Significance of reduction surgery in multidisciplinary treatment of advanced hepatocellular carcinoma with multiple intrahepatic lesions. J Surg Oncol 2003;82:98–103.PubMed Wakabayashi H, et al. Significance of reduction surgery in multidisciplinary treatment of advanced hepatocellular carcinoma with multiple intrahepatic lesions. J Surg Oncol 2003;82:98–103.PubMed
50.
Zurück zum Zitat Takayasu K, et al. Clinical and radiologic assessments of the results of hepatectomy for small hepatocellular carcinoma and therapeutic arterial embolization for postoperative recurrence. Cancer 1989;64:1848–52.PubMed Takayasu K, et al. Clinical and radiologic assessments of the results of hepatectomy for small hepatocellular carcinoma and therapeutic arterial embolization for postoperative recurrence. Cancer 1989;64:1848–52.PubMed
51.
Zurück zum Zitat Okazaki M, et al. Chemoembolotherapy for recurrent hepatocellular carcinoma in the residual liver after hepatectomy. Hepatogastroenterology 1993;40:320–3.PubMed Okazaki M, et al. Chemoembolotherapy for recurrent hepatocellular carcinoma in the residual liver after hepatectomy. Hepatogastroenterology 1993;40:320–3.PubMed
52.
Zurück zum Zitat Bartolozzi C, et al. Treatment of large HCC: transcatheter arterial chemoembolization combined with percutaneous ethanol injection versus repeated transcatheter arterial chemoembolization. Radiology 1995;197:812–8.PubMed Bartolozzi C, et al. Treatment of large HCC: transcatheter arterial chemoembolization combined with percutaneous ethanol injection versus repeated transcatheter arterial chemoembolization. Radiology 1995;197:812–8.PubMed
53.
Zurück zum Zitat Koda M, et al. Combination therapy with transcatheter arterial chemoembolization and percutaneous ethanol injection compared with percutaneous ethanol injection alone for patients with small hepatocellular carcinoma: a randomized control study. Cancer 2001;92:1516–24.PubMed Koda M, et al. Combination therapy with transcatheter arterial chemoembolization and percutaneous ethanol injection compared with percutaneous ethanol injection alone for patients with small hepatocellular carcinoma: a randomized control study. Cancer 2001;92:1516–24.PubMed
54.
Zurück zum Zitat Kamada K, et al. Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma. Am J Surg 2002;184:284–90.PubMed Kamada K, et al. Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma. Am J Surg 2002;184:284–90.PubMed
55.
Zurück zum Zitat Dohmen K, et al. Transcatheter arterial chemoembolization therapy combined with percutaneous ethanol injection for unresectable large hepatocellular carcinoma: an evaluation of the local therapeutic effect and survival rate. Hepatogastroenterology 2001;48:1409–65.PubMed Dohmen K, et al. Transcatheter arterial chemoembolization therapy combined with percutaneous ethanol injection for unresectable large hepatocellular carcinoma: an evaluation of the local therapeutic effect and survival rate. Hepatogastroenterology 2001;48:1409–65.PubMed
56.
Zurück zum Zitat Tanaka K, et al. The long term efficacy of combined transcatheter arterial embolization and percutaneous ethanol injection in the treatment of patients with large hepatocellular carcinoma and cirrhosis. Cancer 1998;82:78–85.PubMed Tanaka K, et al. The long term efficacy of combined transcatheter arterial embolization and percutaneous ethanol injection in the treatment of patients with large hepatocellular carcinoma and cirrhosis. Cancer 1998;82:78–85.PubMed
57.
Zurück zum Zitat Lencioni R, et al. Combined transcatheter arterial chemoembolization and percutaneous ethanol injection for the treatment of large hepatocellular carcinoma: local therapeutic effect and long-term survival rate. Eur Radiol 1998;8:439–44.PubMed Lencioni R, et al. Combined transcatheter arterial chemoembolization and percutaneous ethanol injection for the treatment of large hepatocellular carcinoma: local therapeutic effect and long-term survival rate. Eur Radiol 1998;8:439–44.PubMed
58.
Zurück zum Zitat Akamatsu M, et al. Evaluation of transcatheter arterial embolization prior to percutaneous tumor ablation in patients with hepatocellular carcinoma: a randomized controlled trial. Liver Int 2004;24:625–9.PubMed Akamatsu M, et al. Evaluation of transcatheter arterial embolization prior to percutaneous tumor ablation in patients with hepatocellular carcinoma: a randomized controlled trial. Liver Int 2004;24:625–9.PubMed
59.
Zurück zum Zitat Marelli L. Treatment outcomes for hepatocellular carcinoma using chemoembolization in combination with other therapies. Cancer Treat Rev 2006;32:594–606.PubMed Marelli L. Treatment outcomes for hepatocellular carcinoma using chemoembolization in combination with other therapies. Cancer Treat Rev 2006;32:594–606.PubMed
60.
Zurück zum Zitat Yeung YP, et al. Natural history of untreated nonsurgical hepatocellular carcinoma. Am J Gastroenterol 2005;100:1995–2004.PubMed Yeung YP, et al. Natural history of untreated nonsurgical hepatocellular carcinoma. Am J Gastroenterol 2005;100:1995–2004.PubMed
61.
Zurück zum Zitat Arai K, et al. Efficacy of transcatheter arterial embolization therapy for small hepatocellular carcinomas: comparison with other treatments. Radiat Med 1990;8:191–8.PubMed Arai K, et al. Efficacy of transcatheter arterial embolization therapy for small hepatocellular carcinomas: comparison with other treatments. Radiat Med 1990;8:191–8.PubMed
62.
Zurück zum Zitat Jang MK, et al. Role of additional angiography and chemoembolization in patients with hepatocellular carcinoma who achieved complete necrosis following transarterial chemoembolization. J Gastroenterol Hepatol 2004;19:1074–80.PubMed Jang MK, et al. Role of additional angiography and chemoembolization in patients with hepatocellular carcinoma who achieved complete necrosis following transarterial chemoembolization. J Gastroenterol Hepatol 2004;19:1074–80.PubMed
63.
Zurück zum Zitat Brown DB, et al. Comparison of MELD and Child-Pugh scores to predict survival after chemoembolization for hepatocellular carcinoma. J Vasc Interv Radiol 2004;15:1209–18.PubMedCrossRef Brown DB, et al. Comparison of MELD and Child-Pugh scores to predict survival after chemoembolization for hepatocellular carcinoma. J Vasc Interv Radiol 2004;15:1209–18.PubMedCrossRef
64.
Zurück zum Zitat O’Suilleabhain CB, et al. Factors predictive of 5-year survival after transarterial chemoembolization for inoperable hepatocellular carcinoma. Br J Surg 2003;90:325–31.PubMed O’Suilleabhain CB, et al. Factors predictive of 5-year survival after transarterial chemoembolization for inoperable hepatocellular carcinoma. Br J Surg 2003;90:325–31.PubMed
65.
Zurück zum Zitat Pelletier G, et al. A randomized trial of hepatic arterial chemoembolization in patients with unresectable hepatocellular carcinoma. J Hepatol 1990;11:181–4.PubMed Pelletier G, et al. A randomized trial of hepatic arterial chemoembolization in patients with unresectable hepatocellular carcinoma. J Hepatol 1990;11:181–4.PubMed
66.
Zurück zum Zitat Lin DY, Liaw YF, Lee TY, Lai CM. Hepatic arterial embolization in patients with unresectable hepatocellular carcinoma -a randomized controlled trial. Gastroenterology 1988 ;94:453–6.PubMed Lin DY, Liaw YF, Lee TY, Lai CM. Hepatic arterial embolization in patients with unresectable hepatocellular carcinoma -a randomized controlled trial. Gastroenterology 1988 ;94:453–6.PubMed
67.
Zurück zum Zitat Groupe d’Etude et de Traitement du Carcinome Hepatocellulaire. A comparison of lipiodol chemoembolization and conservative treatment for unresectable hepatocellular carcinoma. N Engl J Med 1995;332:1256–61. Groupe d’Etude et de Traitement du Carcinome Hepatocellulaire. A comparison of lipiodol chemoembolization and conservative treatment for unresectable hepatocellular carcinoma. N Engl J Med 1995;332:1256–61.
68.
Zurück zum Zitat Geschwind JF, Ramsey DE, Choti MA, Thuluvath PJ, Huncharek MS. Chemoembolization of hepatocellular carcinoma: results of a metaanalysis. Am J Clin Oncol 2003;26:344–9.PubMed Geschwind JF, Ramsey DE, Choti MA, Thuluvath PJ, Huncharek MS. Chemoembolization of hepatocellular carcinoma: results of a metaanalysis. Am J Clin Oncol 2003;26:344–9.PubMed
69.
Zurück zum Zitat Reidy DL, Schwartz JD. Therapy for unresectable hepatocellular carcinoma: review of the randomized clinical trials – I: hepatic arterial embolization and embolization-based therapies in unresectable hepatocellular carcinoma. Anticancer Drugs 2004;15:427–37.PubMed Reidy DL, Schwartz JD. Therapy for unresectable hepatocellular carcinoma: review of the randomized clinical trials – I: hepatic arterial embolization and embolization-based therapies in unresectable hepatocellular carcinoma. Anticancer Drugs 2004;15:427–37.PubMed
70.
Zurück zum Zitat Staunton M, Dodd JD, McCormick PA, Malone DE. Finding evidence-based answers to practical questions in radiology: which patients with inoperable hepatocellular carcinoma will survive longer after transarterial chemoembolization? Radiology 2005;237:404–13.PubMed Staunton M, Dodd JD, McCormick PA, Malone DE. Finding evidence-based answers to practical questions in radiology: which patients with inoperable hepatocellular carcinoma will survive longer after transarterial chemoembolization? Radiology 2005;237:404–13.PubMed
71.
Zurück zum Zitat Llovet JM, Sala M. Non-surgical therapies of hepatocellular carcinoma. Eur J Gastroenterol Hepatol 2005;17:505–13.PubMed Llovet JM, Sala M. Non-surgical therapies of hepatocellular carcinoma. Eur J Gastroenterol Hepatol 2005;17:505–13.PubMed
72.
Zurück zum Zitat Lee HS, et al. Therapeutic efficacy of transcatheter arterial chemoembolization as compared with hepatic resection in hepatocellular carcinoma patients with compensated liver function in a hepatitis B virus-endemic area: a prospective cohort study. J Clin Oncol 2002;20:4459–65.PubMed Lee HS, et al. Therapeutic efficacy of transcatheter arterial chemoembolization as compared with hepatic resection in hepatocellular carcinoma patients with compensated liver function in a hepatitis B virus-endemic area: a prospective cohort study. J Clin Oncol 2002;20:4459–65.PubMed
73.
Zurück zum Zitat Mok KT, et al. Multimodality management of hepatocellular carcinoma larger than 10 cm. J Am Coll Surg 2003;197:730–8.PubMed Mok KT, et al. Multimodality management of hepatocellular carcinoma larger than 10 cm. J Am Coll Surg 2003;197:730–8.PubMed
74.
Zurück zum Zitat Liem MS, Poon RT, Lo CM, Tso WK, Fan ST. Outcome of transarterial chemoembolization in patients with inoperable hepatocellular carcinoma eligible for radiofrequency ablation. World J Gastroenterol 2005;11:4465–71.PubMed Liem MS, Poon RT, Lo CM, Tso WK, Fan ST. Outcome of transarterial chemoembolization in patients with inoperable hepatocellular carcinoma eligible for radiofrequency ablation. World J Gastroenterol 2005;11:4465–71.PubMed
75.
Zurück zum Zitat Wall WJ, Marotta PJ. Surgery and transplantation for hepatocellular cancer. Liver Transpl 2000;6(6 Suppl 2):S16–22.PubMed Wall WJ, Marotta PJ. Surgery and transplantation for hepatocellular cancer. Liver Transpl 2000;6(6 Suppl 2):S16–22.PubMed
76.
Zurück zum Zitat Decaens T, et al. Impact of pretransplantation transarterial chemoembolization on survival and recurrence after liver transplantation for hepatocellular carcinoma. Liver Transpl 2005;11:767–75.PubMed Decaens T, et al. Impact of pretransplantation transarterial chemoembolization on survival and recurrence after liver transplantation for hepatocellular carcinoma. Liver Transpl 2005;11:767–75.PubMed
77.
Zurück zum Zitat Fisher RA, et al. Non-resective ablation therapy for hepatocellular carcinoma: effectiveness measured by intention-to-treat and dropout from liver transplant waiting list. Clin Transplant 2004;18:502–12.PubMed Fisher RA, et al. Non-resective ablation therapy for hepatocellular carcinoma: effectiveness measured by intention-to-treat and dropout from liver transplant waiting list. Clin Transplant 2004;18:502–12.PubMed
78.
Zurück zum Zitat Herber S, et al. TACE: therapy of the HCC before liver transplantation—experiences. (in German) Rofo 2005;177:681–90.PubMed Herber S, et al. TACE: therapy of the HCC before liver transplantation—experiences. (in German) Rofo 2005;177:681–90.PubMed
79.
Zurück zum Zitat Cheng YF, et al. Impact of pre-operative transarterial embolization on the treatment of hepatocellular carcinoma with liver transplantation. World J Gastroenterol 2005;11:1433–38.PubMed Cheng YF, et al. Impact of pre-operative transarterial embolization on the treatment of hepatocellular carcinoma with liver transplantation. World J Gastroenterol 2005;11:1433–38.PubMed
80.
Zurück zum Zitat Roche A, et al. Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors. Eur Radiol 2003;13:136–40. Epub 2002 Jul 23.PubMed Roche A, et al. Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors. Eur Radiol 2003;13:136–40. Epub 2002 Jul 23.PubMed
81.
Zurück zum Zitat Zimmer C, Kienbaum P, Wiesemes R, Peters J. Somatostatin does not prevent serotonin release and flushing during chemoembolization of carcinoid liver metastases. Anesthesiology 2003;98:1007–11.PubMed Zimmer C, Kienbaum P, Wiesemes R, Peters J. Somatostatin does not prevent serotonin release and flushing during chemoembolization of carcinoid liver metastases. Anesthesiology 2003;98:1007–11.PubMed
82.
Zurück zum Zitat Ahlman H, Nilsson O, Olausson M. Interventional treatment of the carcinoid syndrome. Neuroendocrinology 2004;80(Suppl 1):67–73.PubMed Ahlman H, Nilsson O, Olausson M. Interventional treatment of the carcinoid syndrome. Neuroendocrinology 2004;80(Suppl 1):67–73.PubMed
83.
Zurück zum Zitat Gupta S, et al. Hepatic arterial embolization and chemoembolization for the treatment of patients with metastatic neuroendocrine tumors: variables affecting response rates and survival. Cancer 2005;104:1590–1602.PubMed Gupta S, et al. Hepatic arterial embolization and chemoembolization for the treatment of patients with metastatic neuroendocrine tumors: variables affecting response rates and survival. Cancer 2005;104:1590–1602.PubMed
84.
Zurück zum Zitat Venook AP. Embolization and chemoembolization therapy for neuroendocrine tumors. Curr Opin Oncol 1999;11:38–41.PubMed Venook AP. Embolization and chemoembolization therapy for neuroendocrine tumors. Curr Opin Oncol 1999;11:38–41.PubMed
85.
Zurück zum Zitat O’Toole D, Ruszniewski P. Chemoembolization and other ablative therapies for liver metastases of gastrointestinal endocrine tumours. Best Pract Res Clin Gastroenterol 2005;19:585–94.PubMed O’Toole D, Ruszniewski P. Chemoembolization and other ablative therapies for liver metastases of gastrointestinal endocrine tumours. Best Pract Res Clin Gastroenterol 2005;19:585–94.PubMed
86.
Zurück zum Zitat Kulke M. Advances in the treatment of neuroendocrine tumors. Curr Treat Options Oncol 2005;6:397–409.PubMed Kulke M. Advances in the treatment of neuroendocrine tumors. Curr Treat Options Oncol 2005;6:397–409.PubMed
87.
Zurück zum Zitat Touzios JG, et al. Neuroendocrine hepatic metastases: does aggressive management improve survival? Ann Surg 2005;241:776–83.PubMed Touzios JG, et al. Neuroendocrine hepatic metastases: does aggressive management improve survival? Ann Surg 2005;241:776–83.PubMed
88.
Zurück zum Zitat Meij V, et al. Local treatment in unresectable hepatic metastases of carcinoid tumors: Experiences with hepatic artery embolization and radiofrequency ablation. World J Surg Oncol 2005;3:75.PubMed Meij V, et al. Local treatment in unresectable hepatic metastases of carcinoid tumors: Experiences with hepatic artery embolization and radiofrequency ablation. World J Surg Oncol 2005;3:75.PubMed
89.
Zurück zum Zitat Moertel CG, et al. The management of patients with advanced carcinoid tumors and islet cell carcinomas. Ann Intern Med 1994;120:302–9.PubMed Moertel CG, et al. The management of patients with advanced carcinoid tumors and islet cell carcinomas. Ann Intern Med 1994;120:302–9.PubMed
90.
Zurück zum Zitat Hirshberg B, et al. Malignant insulinoma: spectrum of unusual clinical features. Cancer 2005;104:264–72.PubMed Hirshberg B, et al. Malignant insulinoma: spectrum of unusual clinical features. Cancer 2005;104:264–72.PubMed
91.
Zurück zum Zitat Nesovic M, Ciric J, Radojkovic S, Zarkovic M, Durovic M. Improvement of metastatic endocrine tumors of the pancreas by hepatic artery chemoembolization. J Endocrinol Invest 1992;15:543–7.PubMed Nesovic M, Ciric J, Radojkovic S, Zarkovic M, Durovic M. Improvement of metastatic endocrine tumors of the pancreas by hepatic artery chemoembolization. J Endocrinol Invest 1992;15:543–7.PubMed
92.
Zurück zum Zitat Starke A, et al. Malignant metastatic insulinoma-postoperative treatment and follow-up. World J Surg 2005;29:789–93.PubMed Starke A, et al. Malignant metastatic insulinoma-postoperative treatment and follow-up. World J Surg 2005;29:789–93.PubMed
93.
Zurück zum Zitat Scott A, Hinwood D, Donnelly R. Radio-frequency ablation for symptom control in a patient with metastatic pancreatic insulinoma. Clin Endocrinol 2002;56:557–9. Scott A, Hinwood D, Donnelly R. Radio-frequency ablation for symptom control in a patient with metastatic pancreatic insulinoma. Clin Endocrinol 2002;56:557–9.
94.
Zurück zum Zitat Civera Andres M, Real Collado JT, Martinez Uso I, Ampudia Blasco FJ, Carmena Rodriguez R. Selective therapeutic embolization in malignant insulinoma (in Spanish). Rev Clin Esp 2000;200:548–50.PubMed Civera Andres M, Real Collado JT, Martinez Uso I, Ampudia Blasco FJ, Carmena Rodriguez R. Selective therapeutic embolization in malignant insulinoma (in Spanish). Rev Clin Esp 2000;200:548–50.PubMed
95.
Zurück zum Zitat Sato T, et al. Strategy for pancreatic endocrine tumors. Hepatogastroenterology 2000;47:537–9.PubMed Sato T, et al. Strategy for pancreatic endocrine tumors. Hepatogastroenterology 2000;47:537–9.PubMed
96.
Zurück zum Zitat Roche A, et al. Prognostic factors for chemoembolization in liver metastasis from endocrine tumors. Hepatogastroenterology 2004;51:1751–6.PubMed Roche A, et al. Prognostic factors for chemoembolization in liver metastasis from endocrine tumors. Hepatogastroenterology 2004;51:1751–6.PubMed
97.
Zurück zum Zitat Brentjens R, Saltz L. Islet cell tumors of the pancreas: the medical oncologist’s perspective. Surg Clin North Am 2001;81:527–42.PubMed Brentjens R, Saltz L. Islet cell tumors of the pancreas: the medical oncologist’s perspective. Surg Clin North Am 2001;81:527–42.PubMed
99.
Zurück zum Zitat Azimuddin K, Chamberlain RS. The surgical management of pancreatic neuroendocrine tumors. Surg Clin North Am 2001;81:511–25.PubMed Azimuddin K, Chamberlain RS. The surgical management of pancreatic neuroendocrine tumors. Surg Clin North Am 2001;81:511–25.PubMed
100.
Zurück zum Zitat Plöckinger U, et al. European Neuroendocrine Tumour Society. Guidelines for the diagnosis and treatment of neuroendocrine gastrointestinal tumours. A consensus statement on behalf of the European Neuroendocrine Tumour Society (ENETS). Neuroendocrinology 2004;80:394–424. Epub 2005 Apr 18.PubMed Plöckinger U, et al. European Neuroendocrine Tumour Society. Guidelines for the diagnosis and treatment of neuroendocrine gastrointestinal tumours. A consensus statement on behalf of the European Neuroendocrine Tumour Society (ENETS). Neuroendocrinology 2004;80:394–424. Epub 2005 Apr 18.PubMed
101.
Zurück zum Zitat Hage R, de la Riviere AB, Seldenrijk CA, van den Bosch JM. Update in pulmonary carcinoid tumors: a review article. Ann Surg Oncol 2003;10:697–704.PubMed Hage R, de la Riviere AB, Seldenrijk CA, van den Bosch JM. Update in pulmonary carcinoid tumors: a review article. Ann Surg Oncol 2003;10:697–704.PubMed
102.
Zurück zum Zitat Chamberlain RS, et al. Hepatic neuroendocrine metastases: does intervention alter outcomes? J Am Coll Surg 2000;190:432–45.PubMed Chamberlain RS, et al. Hepatic neuroendocrine metastases: does intervention alter outcomes? J Am Coll Surg 2000;190:432–45.PubMed
103.
Zurück zum Zitat Lorenz K, et al. Selective arterial chemoembolization for hepatic metastases from medullary thyroid carcinoma. Surgery 2005;138:986–93.PubMed Lorenz K, et al. Selective arterial chemoembolization for hepatic metastases from medullary thyroid carcinoma. Surgery 2005;138:986–93.PubMed
104.
Zurück zum Zitat Ohtsuka Y, et al. Optimal strategy of preoperative transcatheter arterial chemoembolization for hepatoblastoma. Surg Today 2004;34:127–33.PubMed Ohtsuka Y, et al. Optimal strategy of preoperative transcatheter arterial chemoembolization for hepatoblastoma. Surg Today 2004;34:127–33.PubMed
105.
Zurück zum Zitat Warmann S, et al. Interventional treatment of infantile hepatic hemangioendothelioma. J Pediatr Surg 2003;38:1177–81.PubMed Warmann S, et al. Interventional treatment of infantile hepatic hemangioendothelioma. J Pediatr Surg 2003;38:1177–81.PubMed
106.
Zurück zum Zitat Malogolowkin MH, Stanley P, Steele DA, Ortega JA. Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 2000;18:1279–84.PubMed Malogolowkin MH, Stanley P, Steele DA, Ortega JA. Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 2000;18:1279–84.PubMed
107.
Zurück zum Zitat Arcement CM, et al. Intrahepatic chemoembolization in unresectable pediatric liver malignancies. Pediatr Radiol 2000;30:779–85.PubMed Arcement CM, et al. Intrahepatic chemoembolization in unresectable pediatric liver malignancies. Pediatr Radiol 2000;30:779–85.PubMed
108.
Zurück zum Zitat Lee SC, Chung JW, Kim KH, Kim WK. Successful transumbilical embolization of congenitally ruptured hepatoblastoma. J Pediatr Surg 1999;34:1851–52.PubMed Lee SC, Chung JW, Kim KH, Kim WK. Successful transumbilical embolization of congenitally ruptured hepatoblastoma. J Pediatr Surg 1999;34:1851–52.PubMed
109.
Zurück zum Zitat Weintraub M, et al. Successful treatment of progressive stage 4s hepatic neuroblastoma in a neonate with intra-arterial chemoembolization. Pediatr Blood Cancer 2004;43:148–51.PubMed Weintraub M, et al. Successful treatment of progressive stage 4s hepatic neuroblastoma in a neonate with intra-arterial chemoembolization. Pediatr Blood Cancer 2004;43:148–51.PubMed
110.
Zurück zum Zitat Yokoi Y, et al. Aggressive hepatectomy for complete remission of metastatic germ cell tumor following chemotherapy: report of a case. Hepatogastroenterology 2003;50:1136–9.PubMed Yokoi Y, et al. Aggressive hepatectomy for complete remission of metastatic germ cell tumor following chemotherapy: report of a case. Hepatogastroenterology 2003;50:1136–9.PubMed
111.
Zurück zum Zitat St Peter SD, Moss AA, Huettl EA, Leslie KO, Mulligan DC. Chemoembolization followed by orthotopic liver transplant for epithelioid hemangioendothelioma. Clin Transplant 2003;17:549–53.PubMed St Peter SD, Moss AA, Huettl EA, Leslie KO, Mulligan DC. Chemoembolization followed by orthotopic liver transplant for epithelioid hemangioendothelioma. Clin Transplant 2003;17:549–53.PubMed
112.
Zurück zum Zitat Lang EK, Brown CL Jr. Colorectal metastases to the liver: selective chemoembolization. Radiology 1993;189:417–22.PubMed Lang EK, Brown CL Jr. Colorectal metastases to the liver: selective chemoembolization. Radiology 1993;189:417–22.PubMed
113.
Zurück zum Zitat Martinelli DJ, et al. Utility of embolization or chemoembolization as second-line treatment in patients with advanced or recurrent colorectal carcinoma. Cancer 1994;74:1706–12.PubMed Martinelli DJ, et al. Utility of embolization or chemoembolization as second-line treatment in patients with advanced or recurrent colorectal carcinoma. Cancer 1994;74:1706–12.PubMed
114.
Zurück zum Zitat Salman HS, et al. Randomized phase II trial of embolization therapy versus chemoembolization therapy in previously treated patients with colorectal carcinoma metastatic to the liver. Clin Colorectal Cancer 2002;2:173–9.PubMedCrossRef Salman HS, et al. Randomized phase II trial of embolization therapy versus chemoembolization therapy in previously treated patients with colorectal carcinoma metastatic to the liver. Clin Colorectal Cancer 2002;2:173–9.PubMedCrossRef
115.
Zurück zum Zitat Kameyama M, et al. Delayed washout of intratumor blood flow is associated with good response to intraarterial chemoembolization for liver metastasis of colorectal cancer. Surgery 1993;114:97–101.PubMed Kameyama M, et al. Delayed washout of intratumor blood flow is associated with good response to intraarterial chemoembolization for liver metastasis of colorectal cancer. Surgery 1993;114:97–101.PubMed
116.
Zurück zum Zitat Hunt TM, et al. Prospective randomized controlled trial of hepatic arterial embolization or infusion chemotherapy with 5-fluorouracil and degradable starch microspheres for colorectal liver metastases. Br J Surg 1990;77:779–82.PubMed Hunt TM, et al. Prospective randomized controlled trial of hepatic arterial embolization or infusion chemotherapy with 5-fluorouracil and degradable starch microspheres for colorectal liver metastases. Br J Surg 1990;77:779–82.PubMed
117.
Zurück zum Zitat Burger I, et al. Transcatheter arterial chemoembolization in unresectable cholangiocarcinoma: initial experience in a single institution. J Vasc Interv Radiol 2005;16:353–61.PubMed Burger I, et al. Transcatheter arterial chemoembolization in unresectable cholangiocarcinoma: initial experience in a single institution. J Vasc Interv Radiol 2005;16:353–61.PubMed
118.
Zurück zum Zitat Rajan DK, et al. Sarcomas metastatic to the liver: response and survival after cisplatin, doxorubicin, mitomycin-C, Ethiodol, and polyvinyl alcohol chemoembolization. J Vasc Interv Radiol 2001;12:187–93.PubMed Rajan DK, et al. Sarcomas metastatic to the liver: response and survival after cisplatin, doxorubicin, mitomycin-C, Ethiodol, and polyvinyl alcohol chemoembolization. J Vasc Interv Radiol 2001;12:187–93.PubMed
119.
Zurück zum Zitat Kobayashi K, et al. Hepatic artery chemoembolization for 110 gastrointestinal stromal tumors: response, survival, and prognostic factors. Cancer 2006;107:2833–41.PubMed Kobayashi K, et al. Hepatic artery chemoembolization for 110 gastrointestinal stromal tumors: response, survival, and prognostic factors. Cancer 2006;107:2833–41.PubMed
120.
Zurück zum Zitat Feldman ED, Pingpank JF, Alexander HR Jr. Regional treatment options for patients with ocular melanoma metastatic to the liver. Ann Surg Oncol 2004;11:290–97.PubMed Feldman ED, Pingpank JF, Alexander HR Jr. Regional treatment options for patients with ocular melanoma metastatic to the liver. Ann Surg Oncol 2004;11:290–97.PubMed
121.
Zurück zum Zitat Bedikian AY, et al. Treatment of uveal melanoma metastatic to the liver: a review of the M. D. Anderson Cancer Center experience and prognostic factors. Cancer 1995;76:1665–70.PubMed Bedikian AY, et al. Treatment of uveal melanoma metastatic to the liver: a review of the M. D. Anderson Cancer Center experience and prognostic factors. Cancer 1995;76:1665–70.PubMed
122.
Zurück zum Zitat Agarwala SS, Panikkar R, Kirkwood JM. Phase I/II randomized trial of intrahepatic arterial infusion chemotherapy with cisplatin and chemoembolization with cisplatin and polyvinyl sponge in patients with ocular melanoma metastatic to the liver. Melanoma Res 2004;14:217–22.PubMed Agarwala SS, Panikkar R, Kirkwood JM. Phase I/II randomized trial of intrahepatic arterial infusion chemotherapy with cisplatin and chemoembolization with cisplatin and polyvinyl sponge in patients with ocular melanoma metastatic to the liver. Melanoma Res 2004;14:217–22.PubMed
123.
Zurück zum Zitat Giroux MF, Baum RA, Soulen MC. Chemoembolization of liver metastasis from breast carcinoma. J Vasc Interv Radiol 2004;15:289–91.PubMed Giroux MF, Baum RA, Soulen MC. Chemoembolization of liver metastasis from breast carcinoma. J Vasc Interv Radiol 2004;15:289–91.PubMed
124.
Zurück zum Zitat Li XP, Meng ZQ, Guo WJ, Li J. Treatment for liver metastases from breast cancer: results and prognostic factors. World J Gastroenterol 2005;11:3782–7.PubMed Li XP, Meng ZQ, Guo WJ, Li J. Treatment for liver metastases from breast cancer: results and prognostic factors. World J Gastroenterol 2005;11:3782–7.PubMed
125.
Zurück zum Zitat Braga L, et al. Does hypervascularity of liver metastases as detected on MRI predict disease progression in breast cancer patients? AJR Am J Roentgenol 2004;182:1207–13.PubMed Braga L, et al. Does hypervascularity of liver metastases as detected on MRI predict disease progression in breast cancer patients? AJR Am J Roentgenol 2004;182:1207–13.PubMed
Metadaten
Titel
Liver embolizations in oncology: A review
Part I. Arterial (chemo)embolizations
verfasst von
Peter Gunvén
Publikationsdatum
01.03.2008
Verlag
Humana Press Inc
Erschienen in
Medical Oncology / Ausgabe 1/2008
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-007-0039-3

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