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Sport Sciences for Health

Erschienen in:

26.06.2018 | Original Article

Long-term effects of sprint interval training on expression of cardiac genes involved in energy efficiency

verfasst von: Hossein TaheriChadorneshin, Fatemeh Rostamkhani, Hossein Shirvani

Erschienen in: Sport Sciences for Health | Ausgabe 1/2019

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Abstract

Purpose

The real mechanisms of intensive exercise training-induced energy efficiency have not yet been well examined. Therefore, the aim of the present study was to investigate the effects of sprint interval training (SIT) on gene expression of uncoupling proteins (UCPs) and endothelial nitric oxide synthase (eNOS).

Methods

For this purpose, 16 Albino Wistar rats (250–300 g) were randomly divided into equal groups of control and sprint training. The animals run on treadmill for 10 weeks, 5 days per week at intensity corresponding to 90–95% maximal oxygen consumption. The gene expression of UCP2, UCP3 and eNOS was analyzed by RT-PCR method in hearts. The data were analyzed by independent samples T test at P < 0.05 level.

Results

Sprint interval training significantly decreased mRNA expression of UCP2 (t₁₄ = 4.818, P = 0.001) and UCP3 (t₁₄ = 4.620, P = 0.001) in cardiac muscle of rats. In contrast, mRNA expression of eNOS in cardiac muscle significantly increased following sprint interval training (t₁₄ = 7.967, P = 0.001).

Conclusion

This study elucidates that SIT through reduction in gene expression of uncoupling proteins can improve energy efficiency. But, more studies are needed to confirm this hypothesis.

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Titel: Long-term effects of sprint interval training on expression of cardiac genes involved in energy efficiency
verfasst von: Hossein TaheriChadorneshin
Fatemeh Rostamkhani
Hossein Shirvani
Publikationsdatum: 26.06.2018
Verlag: Springer Milan
Erschienen in: Sport Sciences for Health / Ausgabe 1/2019
Print ISSN: 1824-7490
Elektronische ISSN: 1825-1234
DOI: https://doi.org/10.1007/s11332-018-0480-z

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Long-term effects of sprint interval training on expression of cardiac genes involved in energy efficiency

Abstract

Purpose

Methods

Results

Conclusion

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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