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Erschienen in: European Journal of Trauma and Emergency Surgery 5/2022

06.11.2021 | Original Article

Long-term influence of frailty in elderly patients after surgical emergencies

verfasst von: Alejandro Sánchez Arteaga, José Tinoco González, Luis Tallón Aguilar, Gregorio Anguiano Díaz, Rosa María Jiménez-Rodriguez, Ana Rovira Liarde, Felipe Pareja Ciuró, Javier Padillo Ruíz

Erschienen in: European Journal of Trauma and Emergency Surgery | Ausgabe 5/2022

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Abstract

Purpose

Frailty is known to increase vulnerability to stressful factors, and motivate a higher morbidity and mortality in several health conditions. However, long-term impact of frailty after surgical procedures remains unclear. The purpose of this study was to evaluate the relationship between frailty and long-term clinical outcomes after emergency surgery.

Methods

Prospective cohort study in patients older than 70 years undergoing emergency procedures. A total of 82 patients (mean age 78.5 years, 53.3% women) were consecutively enrolled. Data on demographics, surgical procedures, complications after 30 postoperative days, and frailty according to the clinical frailty scale, Triage Risk Screening Tool (TRST), and FRAIL scale were recorded. Readmission, mortality, and transition to frailty rates were analyzed at 6 and 18 months postoperatively.

Results

The prevalence of frailty ranged between 14.6 and 29.6% depending on the scale used. The overall mortality rate at 18 months was 19.5% (16 patients), and the survival curves demonstrated a significant difference in mortality between frail and non-frail patients assessed using the FRAIL scale and TRST (p = 0.049 and p = 0.033, respectively), with a hazard ratio of 2.28 (95% confidence interval 1.24–6.44). Logistic regression analysis showed that diabetes (p = 0.013) was an independent risk factor for transition to frailty, and antidepressant drug use was close to statistical significance (p = 0.08).

Conclusion

Frailty is a predictive marker of long-term mortality in patients undergoing emergency procedures. Diabetes and depression may represent independent risk factors for transition to frailty over time.
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Metadaten
Titel
Long-term influence of frailty in elderly patients after surgical emergencies
verfasst von
Alejandro Sánchez Arteaga
José Tinoco González
Luis Tallón Aguilar
Gregorio Anguiano Díaz
Rosa María Jiménez-Rodriguez
Ana Rovira Liarde
Felipe Pareja Ciuró
Javier Padillo Ruíz
Publikationsdatum
06.11.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Trauma and Emergency Surgery / Ausgabe 5/2022
Print ISSN: 1863-9933
Elektronische ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-021-01818-6

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