Skip to main content
Erschienen in: Supportive Care in Cancer 2/2018

16.09.2017 | Original Article

Long-term quality of life profile in oncology: a comparison between cancer survivors and the general population

verfasst von: Maria Antonietta Annunziata, Barbara Muzzatti, Cristiana Flaiban, Katiuscia Gipponi, Carlo Carnaghi, Paolo Tralongo, Michele Caruso, Raffaele Cavina, Umberto Tirelli

Erschienen in: Supportive Care in Cancer | Ausgabe 2/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Understanding the quality of life (QoL) of cancer survivors is relevant to both clinical practice and health care policy. The current study compared the QoL profile in this specific population with that of a normative sample for the general population, as well as with those of both healthy and oncological patients normative sub-samples. In addition, associations between the obtained QoL profile and the main socio-demographic and clinical characteristics of the sample were examined.

Methods

Three hundred and ninety-two adult long-term cancer survivors (i.e., people 5 + years from their cancer diagnosis who were free from it and its treatments) were enrolled during follow-up visits and compiled the Short Form 36 Health Survey.

Results

In comparison with the normative data for the adult general population, the present sample showed lower scores in Physical functioning, Role-physical limitation, and Role-emotional limitations (all differences were both statistically and clinically significant); the difference in Vitality was only statistically significant. In all eight SF-36 scales, scores of the present sample were clinically and statistically lower than those of the normative healthy subsample, whereas they were statistically and clinically higher than those of normative subsample which had experienced cancer, except for Role-physical limitation. The QoL profile was associated with gender (p = 0.002), age (p = 0.001), education (p < 0.001), occupational status (p < 0.001), and the presence of other health issues (p < 0.001).

Conclusion

These data support the utility of rehabilitative programs which integrate both healthcare and social interventions. In addition, they encourage the monitoring of the health status of this specific population, within a broad frame which simultaneously takes into consideration health and QoL.
Literatur
1.
Zurück zum Zitat Annunziata MA, Muzzatti B, Giovannini L, Romito F, Cormio C et al (2015) Is long-term cancer survivors’ quality of life comparable to that of the general population? An Italian study. Support Care Cancer 23:2663–2668CrossRefPubMed Annunziata MA, Muzzatti B, Giovannini L, Romito F, Cormio C et al (2015) Is long-term cancer survivors’ quality of life comparable to that of the general population? An Italian study. Support Care Cancer 23:2663–2668CrossRefPubMed
2.
Zurück zum Zitat World Health Organization, QOL GROUP (1993) Study protocol for the World Health Organization project to develop a quality of life assessment instrument (WHOQOL). Qual Life Res 2:153–159CrossRef World Health Organization, QOL GROUP (1993) Study protocol for the World Health Organization project to develop a quality of life assessment instrument (WHOQOL). Qual Life Res 2:153–159CrossRef
3.
Zurück zum Zitat Stein KD, Syrjala KL, Andrykowski MA (2008) Physical and psychological long-term and late effects of cancer. Cancer 112(11 suppl):2577–2592CrossRefPubMed Stein KD, Syrjala KL, Andrykowski MA (2008) Physical and psychological long-term and late effects of cancer. Cancer 112(11 suppl):2577–2592CrossRefPubMed
4.
Zurück zum Zitat Foster C, Wright D, Hill H, Hopkinson J, Roffe L (2009) Psychosocial implications of living 5 years or more following a cancer diagnosis: a systematic review of the research evidence. Eur J Cancer Care (Engl) 18:223–247CrossRef Foster C, Wright D, Hill H, Hopkinson J, Roffe L (2009) Psychosocial implications of living 5 years or more following a cancer diagnosis: a systematic review of the research evidence. Eur J Cancer Care (Engl) 18:223–247CrossRef
5.
Zurück zum Zitat Harrington CB, Hansen JA, Moskowitz M, Todd BL, Feuerstein M (2010) It’s not over when it’s over: long-term symptoms in cancer survivors—a systematic review. Int J Psychiatry Med 40:163–181CrossRefPubMed Harrington CB, Hansen JA, Moskowitz M, Todd BL, Feuerstein M (2010) It’s not over when it’s over: long-term symptoms in cancer survivors—a systematic review. Int J Psychiatry Med 40:163–181CrossRefPubMed
6.
Zurück zum Zitat Wu HS, Harden JK (2015) Symptom burden and quality of life in survivorship: a review of the literature. Cancer Nurs 38:E29–E54CrossRefPubMed Wu HS, Harden JK (2015) Symptom burden and quality of life in survivorship: a review of the literature. Cancer Nurs 38:E29–E54CrossRefPubMed
7.
Zurück zum Zitat Ware JE, Snow KK, Kosinski M, Gandek B (1993) SF-36 health survey-manual and interpretation guide. The Health Institute Boston, MA Ware JE, Snow KK, Kosinski M, Gandek B (1993) SF-36 health survey-manual and interpretation guide. The Health Institute Boston, MA
8.
Zurück zum Zitat Apolone G, Mosconi P, Ware JE (1997) Questionario sullo stato di salute SF-36, manuale d’uso e guida all’interpretazione dei risultati. Guerini e Associati, Milano Apolone G, Mosconi P, Ware JE (1997) Questionario sullo stato di salute SF-36, manuale d’uso e guida all’interpretazione dei risultati. Guerini e Associati, Milano
9.
Zurück zum Zitat Klein D, Mercier M, Abeilard E, Puyraveau M, Danzon A, Dalstein V et al (2011) Long-term quality of life after breast cancer: a French registry-based controlled study. Breast Cancer Res Treat 129:125–134CrossRefPubMed Klein D, Mercier M, Abeilard E, Puyraveau M, Danzon A, Dalstein V et al (2011) Long-term quality of life after breast cancer: a French registry-based controlled study. Breast Cancer Res Treat 129:125–134CrossRefPubMed
10.
Zurück zum Zitat Santin O, Mills M, Treanor C, Donnelly M (2012) A comparative analysis of the health and well-being of cancer survivors to the general population. Support Care Cancer 20:2545–2552CrossRefPubMed Santin O, Mills M, Treanor C, Donnelly M (2012) A comparative analysis of the health and well-being of cancer survivors to the general population. Support Care Cancer 20:2545–2552CrossRefPubMed
11.
Zurück zum Zitat Helgeson VS, Tomich PL (2005) Surviving cancer: a comparison of 5-year disease-free BCS with healthy women. Psychooncology 14:307–317CrossRefPubMed Helgeson VS, Tomich PL (2005) Surviving cancer: a comparison of 5-year disease-free BCS with healthy women. Psychooncology 14:307–317CrossRefPubMed
12.
Zurück zum Zitat Schoormans D, Czene K, Hall P, Brandberg Y (2015) The impact of comorbidity on health-related quality of life in breast cancer survivors and controls. Acta Oncol 54:727–734CrossRefPubMed Schoormans D, Czene K, Hall P, Brandberg Y (2015) The impact of comorbidity on health-related quality of life in breast cancer survivors and controls. Acta Oncol 54:727–734CrossRefPubMed
13.
Zurück zum Zitat Heins MJ, Korevaar JC, Hopman PE, Donker GA, Schellevis FG, Rijken MP (2016) Health-related quality of life and health care use in cancer survivors compared with patients with chronic diseases. Cancer 122:962–970CrossRefPubMed Heins MJ, Korevaar JC, Hopman PE, Donker GA, Schellevis FG, Rijken MP (2016) Health-related quality of life and health care use in cancer survivors compared with patients with chronic diseases. Cancer 122:962–970CrossRefPubMed
14.
Zurück zum Zitat Wikman A, Djärv T, Johar A, Lagergren P (2013) Health-related quality of life does not differ between short-term, long-term and very long-term cancer survivors in the Swedish general population. Psychooncology 22:1369–1374CrossRefPubMed Wikman A, Djärv T, Johar A, Lagergren P (2013) Health-related quality of life does not differ between short-term, long-term and very long-term cancer survivors in the Swedish general population. Psychooncology 22:1369–1374CrossRefPubMed
15.
Zurück zum Zitat Muzzatti B, Flaiban C, Surbone A, Annunziata MA (2015) Quality of life profile in Italian long-term cancer survivors. Qual Life Res 24:959–967CrossRefPubMed Muzzatti B, Flaiban C, Surbone A, Annunziata MA (2015) Quality of life profile in Italian long-term cancer survivors. Qual Life Res 24:959–967CrossRefPubMed
16.
Zurück zum Zitat ESEMeD/MHEDEA 2000 Investigators (2004) Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scan 109(Suppl. 420):21–27CrossRef ESEMeD/MHEDEA 2000 Investigators (2004) Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scan 109(Suppl. 420):21–27CrossRef
17.
Zurück zum Zitat Rodriguez JL, Hawkins NA, Berkowitz Z, Li C (2015) Factors associated with health-related quality of life among colorectal cancer survivors. Am J Prev Med 49(Suppl 5):S518–S527CrossRefPubMed Rodriguez JL, Hawkins NA, Berkowitz Z, Li C (2015) Factors associated with health-related quality of life among colorectal cancer survivors. Am J Prev Med 49(Suppl 5):S518–S527CrossRefPubMed
18.
Zurück zum Zitat Chu WO, Dialla PO, Roignot P, Poillot ML, Coutant C, Arveux P (2016) Determinants of quality of life among long-term breast cancer survivors. Qual Life Res 25:1981–1990CrossRefPubMed Chu WO, Dialla PO, Roignot P, Poillot ML, Coutant C, Arveux P (2016) Determinants of quality of life among long-term breast cancer survivors. Qual Life Res 25:1981–1990CrossRefPubMed
19.
Zurück zum Zitat Laicardi C, Pezzuti L (2000) Psicologia dell’invecchiamento e della longevità [Psychology of ageing and longevity]. Il Mulino Bologna Laicardi C, Pezzuti L (2000) Psicologia dell’invecchiamento e della longevità [Psychology of ageing and longevity]. Il Mulino Bologna
20.
Zurück zum Zitat De Beni R, Borella E (2016) Psicologia dell’invecchiamento e della longevità [Psychology of ageing and longevity]. Il Mulino Bologna De Beni R, Borella E (2016) Psicologia dell’invecchiamento e della longevità [Psychology of ageing and longevity]. Il Mulino Bologna
21.
Zurück zum Zitat Lee SY, Kim SJ, Shin J, Han KT, Park EC (2015) The impact of job status on quality of life: general population versus long-term cancer survivors. Psychooncology 24:1552–1559CrossRefPubMed Lee SY, Kim SJ, Shin J, Han KT, Park EC (2015) The impact of job status on quality of life: general population versus long-term cancer survivors. Psychooncology 24:1552–1559CrossRefPubMed
22.
Zurück zum Zitat Clarke TC, Christ SL, Lee DJ, Arheart KL, Prado G, Martinez AC et al (2015) Working with cancer: health and employment among cancer survivors. Ann Epidemiol 25:832–838CrossRefPubMed Clarke TC, Christ SL, Lee DJ, Arheart KL, Prado G, Martinez AC et al (2015) Working with cancer: health and employment among cancer survivors. Ann Epidemiol 25:832–838CrossRefPubMed
23.
Zurück zum Zitat Smith SK, Crespi CM, Petersen L, Zimmerman S, Ganz PA (2010) The impact of cancer and quality of life for posttreatment non-Hodgkin lymphoma survivors. Psychooncology 19:1259–1267CrossRefPubMedPubMedCentral Smith SK, Crespi CM, Petersen L, Zimmerman S, Ganz PA (2010) The impact of cancer and quality of life for posttreatment non-Hodgkin lymphoma survivors. Psychooncology 19:1259–1267CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Le Borgne G, Mercier M, Woronoff AS, Guizard AV, Abeilard E, Klein D et al (2013) Quality of life in long-term cervical cancer survivors: a population-based study. Gyn Oncol 129:222–228CrossRef Le Borgne G, Mercier M, Woronoff AS, Guizard AV, Abeilard E, Klein D et al (2013) Quality of life in long-term cervical cancer survivors: a population-based study. Gyn Oncol 129:222–228CrossRef
Metadaten
Titel
Long-term quality of life profile in oncology: a comparison between cancer survivors and the general population
verfasst von
Maria Antonietta Annunziata
Barbara Muzzatti
Cristiana Flaiban
Katiuscia Gipponi
Carlo Carnaghi
Paolo Tralongo
Michele Caruso
Raffaele Cavina
Umberto Tirelli
Publikationsdatum
16.09.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 2/2018
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-017-3880-8

Weitere Artikel der Ausgabe 2/2018

Supportive Care in Cancer 2/2018 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.