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Erschienen in: Journal of Gastrointestinal Cancer 1/2013

01.03.2013 | Original Research

Long-Term Results and Prognostic Factors in Resected Pancreatic Body and Tail Adenocarcinomas

verfasst von: Vinayak S. Rohan, Jun-Te Hsu, Keng-Hao Liu, Chun-Nan Yeh, Ta-Sen Yeh, Yi-Yin Jan, Tsann-Long Hwang

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 1/2013

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Abstract

Background

Adenocarcinoma of the body and tail of the pancreas are more often than not inoperable to begin with. Factors predicting the prognosis in the resected tumors of pancreatic body and tail were analyzed.

Methods

Between 1989 and 2006, 43 patients with adenocarcinoma of the body and tail of the pancreas underwent resection at Chang Gung Memorial Hospital, Taoyuan, Taiwan. Univariate and multivariate analysis of clinicopathological factors affecting the prognosis were analyzed.

Results

Totally, 32 patients were available for the analysis. The median follow-up was 13.6 months (1.5–87.5 months). The median survival time was 14.2 months and the 1-, 3-, and 5-year survival rates were 58.1, 25.8, and 6.5 %, respectively. On univariate analysis, the factors which influenced the survival were tumor size >4 cm (p = 0.004), lymphatic invasion (p = 0.001), and positive resection margin (p = 0.030). On multivariate analysis, only the tumor size and the lymphatic invasion were independent prognostic factors.

Conclusion

Even after macroscopic curative resection, the prognosis remains poor for pancreatic body and tail adenocarcinoma. Early diagnosis is the key to achieving long-term survival. Newer effective adjuvant treatment after curative resection is needed to improve the survival
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Metadaten
Titel
Long-Term Results and Prognostic Factors in Resected Pancreatic Body and Tail Adenocarcinomas
verfasst von
Vinayak S. Rohan
Jun-Te Hsu
Keng-Hao Liu
Chun-Nan Yeh
Ta-Sen Yeh
Yi-Yin Jan
Tsann-Long Hwang
Publikationsdatum
01.03.2013
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Cancer / Ausgabe 1/2013
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-012-9448-4

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