Background
Methods
Study design and population
Questionnaires
QOL
Fatigue
Donor specific questions
Demographic variables
Statistical analyses
Results
Demographics and relationship to the recipient
All donors | <70 years | >70 years | |||||
---|---|---|---|---|---|---|---|
n
|
n
|
n
|
p
| ||||
Donors | 217 | (100 %) | 183 | (84.3 %) | 34 | (15.7 %) | |
Gender | 0.59 | ||||||
Female | 138 | (63.6 %) | 115 | (62.8 %) | 23 | (67.6 %) | |
Male | 79 | (36.4 %) | 68 | (37.2 %) | 11 | (32.4 %) | |
Marital status | 0.04* | ||||||
Single/divorced/widowed | 52 | (24 %) | 39 | (21.3 %) | 13 | (38.2 %) | |
Married/cohabitant | 164 | (75.6 %) | 143 | (78.1 %) | 21 | (61.8 %) | |
Educational level | 0.88 | ||||||
High school or less | 120 | (55.3 %) | 101 | (55.2 %) | 19 | (55.9 %) | |
College or university | 93 | (42.9 %) | 79 | (43.2 %) | 14 | (41.2 %) | |
Vocational status | 0.00* | ||||||
Employed | 147 | (67.7 %) | 139 | (76 %) | 7 | (20.6 %) | |
Not employed | 70 | (32.3 %) | 42 | (23 %) | 27 | (79.4 %) | |
Donor’s relation to recipient | 0.04* | ||||||
Offspring | 23 | (10.6 %) | 22 | (12.0 %) | 1 | (2.9 %) | |
Parents | 53 | (24.4 %) | 39 | (21.3 %) | 14 | (41.2 %) | |
Sibling | 73 | (33.6 %) | 64 | (35.0 %) | 8 | (23.5 %) | |
Spouse | 37 | (17.1 %) | 29 | (15.8 %) | 8 | (23.5 %) | |
Other | 31 | (14.3 %) | 27 | (14.8 %) | 3 | (8.8 %) |
QOL
SF-36 Subscales | Total sample | Age groups | Gender | |||||
---|---|---|---|---|---|---|---|---|
Mean (SD) |
n
| <70y | ≥70y |
P
| Male | Female |
P
| |
Physical function | 208 | 89.7 (15.7) | 90.1 (15.2) | 86.1 (19.2) | 0.29 | 92.4 (12.1) | 87.8 (17.6) | 0.13 |
Role physical | 214 | 86.3 (24.2) | 85.8 (24.8) | 86.6 (25.1) | 0.36 | 91.8 (20.7) | 82.4 (26.4) | 0.01* |
Bodily pain | 216 | 76.8 (26.0) | 76.8 (26.2) | 79.1 (25.7) | 0.76 | 81.5 (22.9) | 74.5 (27.5) | 0.11 |
General health | 213 | 80.5 (21.0) | 81.6 (20.4) | 78.5 (22.2) | 0.16 | 85.6 (15.8) | 78.6 (22.7) | 0.12 |
Vitality | 214 | 63.9 (22.9) | 64.3 (23.4) | 62.0 (23.3) | 0.38 | 68.2 (22.2) | 61.5 (23.7) | 0.11 |
Social function | 214 | 88.9 (20.2) | 89.4 (19.7) | 86.1 (23.1) | 0.23 | 91.9 (16.5) | 87.2 (21.9) | 0.17 |
Role emotional | 216 | 91.4 (17.0) | 91.6 (17.2) | 89.2 (19.3) | 0.13 | 95.3 (10.9) | 88.9 (20.1) | 0.03* |
Mental health | 216 | 82.6 (16.1) | 82.7 (16.2) | 82.0 (15.9) | 0.43 | 84.9 (15.1) | 81.3 (16.7) | 0.20 |
Fatigue
MFI Scale scores | Total sample | Age groups | Gender | |||||
---|---|---|---|---|---|---|---|---|
Mean (SD) |
n
| <70y | ≥70y |
p
| Male | Female |
P
| |
General fatigue | 207 | 8.8 (4.4) | 8.8 (4.5) | 8.4 (4.0) | 0.89 | 7.7 (3.8) | 9.3 (4.6) | 0.01* |
Physical fatigue | 209 | 8.2 (4.2) | 8.1 (4.1) | 8.7 (4.5) | 0.28 | 7.3 (3.6) | 8.7 (4.4) | 0.01* |
Reduced activity | 211 | 8.3 (4.1) | 8.2 (3.9) | 8.6 (4.3) | 0.26 | 7.7 (3.5) | 8.5 (4.2) | 0.09 |
Reduced motivation | 208 | 7.3 (3.1) | 7.1 (3.0) | 7.0 (2.6) | 0.61 | 6.7 (2.9) | 7.4 (3.0) | 0.04* |
Mental fatigue | 212 | 8.0 (3.5) | 8.0 (3.6) | 8.1 (2.9) | 0.25 | 7.4 (3.5) | 8.3 (3.5) | 0.03* |
Donor specific questions
Physical functiona
| Role physicalb
| Bodily painb
| General healtha
| Vitalityb
| Social functiona
| Role emotionala
| Mental healtha
| ||
---|---|---|---|---|---|---|---|---|---|
n
| 159 | 164 | 166 | 163 | 163 | 167 | 166 | 166 | |
Recognition | |||||||||
Family and friends | B (st.error) | 3.242 (2.004) | 7.984* (4.029) | 7.490* (3.153) | 0.063 (0.041) | 6.776* (3.077) | 0.048 (0.039) | 0.055* (0.028) | 0.045 (0.030) |
Health personnel | B (st.error) | 0.342 (1.322) | 1.527 (2.830) | 2.890 (2.496) | 0.001 (0.027) | 0.949 (2.266) | 0.010 (0.025) | 0.009 (0.017) | 0.014 (0.020) |
Recipient’s outcome | |||||||||
Still alive | B (st.error) | 1.458 (4.705) | 0.499 (9.913) | 5.959 (8.205) | −0.027 (0.097) | 0.363 (7.799) | 0.036 (0.092) | 0.034 (0.064) | 0.075 (0.071) |
Responsibility | |||||||||
Feeling responsible for recipient’s health | B (st.error) | −0.612 (1.093) | 3.277 (2.420) | 1.271 (2.100) | 0.008 (0.023) | 0.754 (1.862) | 0.020 (0.021) | 0.021 (0.015) | 0.003 (0.016) |
Donor’s relationc
| |||||||||
Offspring | B (st.error) | −0.126 (4.556) | 2.923 (9.282) | 1.725 (8.156) | 0.054 (0.094) | −4.816 (7.850) | −0.149 (0.089) | −0.066 (0.062) | −0.041 (0.070) |
Parents | B (st.error) | 0.021 (3.974) | 8.459 (8.275) | 8.052 (7.699) | 0.068 (0.082) | −5.203 (7.059) | −0.104 (0.077) | −0.023 (0.054) | −0.001 (0.061) |
Sibling | B (st.error) | −0.777 (3.553) | 3.039 (7.351) | 3.450 (6.724) | 0.040 (0.074) | −0.410 (6.417) | −0.097 (0.069) | −0.001 (0.048) | 0.016 (0.054) |
Spouse | B (st.error) | −1.627 (4.201) | 4.645 (8.266) | 3.094 (7.602) | 0.031 (0.084) | −5.367 (7.041) | −0.121 (0.080) | −0.052 (0.056) | −0.031 (0.062) |
Use of analgesicd
| |||||||||
Daily/every week | B (st.error) | −8.034* (4.001) | −15.978 (8.639) | −20.299** (7.117) | −0.057 (0.081) | −4.438 (6.827) | −0.042 (0.077) | −0.096 (0.054) | 0.005 (0.061) |
Use of relaxant/ sleeping pillse
| |||||||||
Daily/every week | B (st.error) | −17.378** (4.817) | −11.263 (8.498) | −0.169 (8.631) | −0.116 (0.093) | −17.494** (6.437) | −0.095 (0.086) | −0.133* (0.060) | −0.099 (0.070) |
Genderf
| |||||||||
Male | B (st.error) | 4.355 (2.532) | 6.980 (5.889) | 3.118 (5.011) | 0.079 (0.053) | 4.853 (4.832) | 0.044 (0.050) | 0.045 (0.035) | 0.035 (0.039) |
Agegroupg
| |||||||||
<70 years | B (st.error) | 4.419 (4.060) | 3.637 (8.356) | 7.450 (7.430) | 0.070 (0.082) | 5.565 (6.824) | 0.079 (0.077) | 0.076 (0.054) | 0.020 (0.060) |
Medical follow-uph
| |||||||||
No regular controls | B (st.error) | −2.743 (2.360) | −2.947 (4.985) | −0.842 (4.419) | −0.062 (0.049) | 0.016 (4.417) | 0.018 (0.046) | −0.028 (0.032) | −0.011 (0.036) |
General fatiguea
| Physical fatigueb
| Reduced activitya
| Reduced motivationa
| Mental fatiguea
| ||
---|---|---|---|---|---|---|
n
| 163 | 163 | 163 | 161 | 164 | |
Recognition | ||||||
Family and friends | B (st.error) | −0.021 (0.080) | 0.066 (0.425) | −0.003 (0.058) | 0.038 (0.049) | −0.016 (0.054) |
Health personnel | B (st.error) | −0.038 (0.038) | −0.130 0.264 | 0.010 (0.039) | −0.012 (0.030) | −0.038 (0.034) |
Recipient’s outcome | ||||||
Still alive | B (st.error) | 0.113 (0.141) | −0.172 (1.060) | 0.011 (0.133) | 0.086 (0.110) | 0.363** (0.126) |
Responsibility | ||||||
Feeling responsible for recipient’s health | B (st.error) | 0.051 (0.033) | 0.095 (0.238) | 0.002 (0.032) | −0.008 (0.026) | −0.015 (0.030) |
Donor’s relationc
| ||||||
Offspring | B (st.error) | −0.025 (0.135) | 0.952 (0.895) | 0.218 (0.130) | 0.023 (0.107) | 0.110 (0.122) |
Parents | B (st.error) | −0.005 (0.118) | 0.660 (0.763) | 0.103 (0.114) | −0.001 (0.092) | −0.047 (0.106) |
Sibling | B (st.error) | 0.064 (0.104) | 0.832 (0.653) | 0.140 (0.099) | 0.094 (0.082) | 0.040 (0.094) |
Spouse | B (st.error) | 0.135 (0.126) | 0.366 (0.809) | 0.208 (0.119) | 0.067 (0.099) | 0.091 (0.111) |
Use of analgesicd
| ||||||
Daily/ every week | B (st.error) | 0.356** (0.115) | 3.599** (1.168) | 0.258* (0.110) | 0.071 (0.094) | 0.158 (0.104) |
Use of relaxant/ sleeping pillse
| ||||||
Daily/ every week | B (st.error) | 0.261* (0.128) | 2.552* (1.277) | 0.321* (0.125) | 0.363*** (0.103) | 0.161 (0.116) |
Genderf
| ||||||
Male | B (st.error) | −0.196* (0.078) | −1.139* (0.489) | −0.037 (0.072) | −0.072 (0.060) | −0.068 (0.068) |
Agegroupg
| ||||||
<70 years | B (st.error) | −0.088 (0.117) | −1.298 (0.889) | 0.017 (0.114) | 0.016 (0.092) | −0.093 (0.103) |
Medical follow-uph
| ||||||
No regular controls | B (st.error) | −0.009 (0.071) | 0.299 (0.476) | −0.006 (0.068) | −0.009 (0.055) | −0.078 (0.063) |