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Erschienen in: Community Mental Health Journal 8/2017

10.02.2017 | Original Paper

Longer Duration of Untreated Psychosis Hinders Improvement in Treatment of Chronic Schizophrenia: Community Based Early Intervention is an Evidence Based Option

verfasst von: Abdülkadir Tabo, Erkan Aydın, Hüseyin Yumrukçal, Sadık Yiğit, Uğraş Erman Uzun, Oğuz Karamustafalıoğlu

Erschienen in: Community Mental Health Journal | Ausgabe 8/2017

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Abstract

To determine the effects of community-based mental health services on the quality of life and disease symptoms of chronic schizophrenia patients and to determine the effects of duration of untreated psychosis on outcome. The first year records of schizophrenia patients who had been followed up at Zeytinburnu CMHC for at least 12 months, have been used to asses outcome using initial and 12th month quality of life (QoL), positive and negative symptom scale (PANSS) scores. Highly significant improvements were shown in the QoL and PANSS scores. There were significant differences between the two study groups (duration of untreated psychosis >2 years, versus duration of untreated psychosis <2 years) in terms of improvements in QoL and PANSS scores. Formation of early intervention teams that seek to provide preventive activities (i.e. for schizophrenia) in countries that have changed to community based mental health systems is a sound mental health implementation.
Literatur
Zurück zum Zitat Baronet, A.-M., & Gerber, G.J. (1998).Psychiatric rehabilitation: Efficacy of four models. Clinical Psychology Review, 18, 189–228.CrossRefPubMed Baronet, A.-M., & Gerber, G.J. (1998).Psychiatric rehabilitation: Efficacy of four models. Clinical Psychology Review, 18, 189–228.CrossRefPubMed
Zurück zum Zitat Bottlender, R., Sato, T., Jager, M., Wegener, U., Wittmann, J., Strauss, A., et al. (2003). The impact of the duration of untreated psychosis prior to first psychiatric admission on the 15-year outcome in schizophrenia. Schizophrenia research, 62(1–2), 37–44.CrossRefPubMed Bottlender, R., Sato, T., Jager, M., Wegener, U., Wittmann, J., Strauss, A., et al. (2003). The impact of the duration of untreated psychosis prior to first psychiatric admission on the 15-year outcome in schizophrenia. Schizophrenia research, 62(1–2), 37–44.CrossRefPubMed
Zurück zum Zitat Broussard, B., Kelley, M.E., Wan, C.R., Cristofaro, S.L., Crisafio, A., Haggard, P.J., et al. (2013). Demographic, socio-environmental and substance-related predictors of duration of untreated psychosis (DUP). Schizophrenia Research, 148(0), 93–98.CrossRefPubMedPubMedCentral Broussard, B., Kelley, M.E., Wan, C.R., Cristofaro, S.L., Crisafio, A., Haggard, P.J., et al. (2013). Demographic, socio-environmental and substance-related predictors of duration of untreated psychosis (DUP). Schizophrenia Research, 148(0), 93–98.CrossRefPubMedPubMedCentral
Zurück zum Zitat Chang, L.R., Lin, Y.H., Chang, H.C., Chen, Y.Z., Haung, W.L., Liu, C. M., et al. (2013). Psychopathology, rehospitalization and quality of life among patients with schizophrenia under home care case management in Taiwan. Journal of the Formosan Medical Association, 112(1–3), 208–215.CrossRefPubMed Chang, L.R., Lin, Y.H., Chang, H.C., Chen, Y.Z., Haung, W.L., Liu, C. M., et al. (2013). Psychopathology, rehospitalization and quality of life among patients with schizophrenia under home care case management in Taiwan. Journal of the Formosan Medical Association, 112(1–3), 208–215.CrossRefPubMed
Zurück zum Zitat Dominguez, M.D., Fisher, H.L., Major, B., Chisholm, B., Rahaman, N., Joyce, J.,et al. (2013). Duration of untreated psychosis in adolescents: Ethnic differences and clinical profiles. Schizophrenia Research, 150(2–3), 526–532.CrossRefPubMed Dominguez, M.D., Fisher, H.L., Major, B., Chisholm, B., Rahaman, N., Joyce, J.,et al. (2013). Duration of untreated psychosis in adolescents: Ethnic differences and clinical profiles. Schizophrenia Research, 150(2–3), 526–532.CrossRefPubMed
Zurück zum Zitat Harris, M.G., Henry, L.P., Harrigan, S.M., Purcell, R., Schwartz, O.S., Farrelly, S.E., et al. (2005). The relationship between duration of untreated psychosis and outcome: An eight-year prospective study. Schizophrenia research, 79(1), 85–93.CrossRefPubMed Harris, M.G., Henry, L.P., Harrigan, S.M., Purcell, R., Schwartz, O.S., Farrelly, S.E., et al. (2005). The relationship between duration of untreated psychosis and outcome: An eight-year prospective study. Schizophrenia research, 79(1), 85–93.CrossRefPubMed
Zurück zum Zitat Heinrichs, D.W., Hanlon, T.E., & Carpenter, W.T. (1984). The quality of life scale: An instrument for rating the schizophrenic deficit syndrome. Schizophrenia Bulletin, 10(3), 388–398.CrossRefPubMed Heinrichs, D.W., Hanlon, T.E., & Carpenter, W.T. (1984). The quality of life scale: An instrument for rating the schizophrenic deficit syndrome. Schizophrenia Bulletin, 10(3), 388–398.CrossRefPubMed
Zurück zum Zitat Holloway, F., Oliver, N., Collins, E., & Carson, J. (1995). Case Management : A critical review of the outcome literature. European Psychiatry: The Journal of the Association of European Psychiatrists, 10(3), 113–128.CrossRef Holloway, F., Oliver, N., Collins, E., & Carson, J. (1995). Case Management : A critical review of the outcome literature. European Psychiatry: The Journal of the Association of European Psychiatrists, 10(3), 113–128.CrossRef
Zurück zum Zitat Honkonen, T., Saarinen, S., & Salokangas, R.K. (1999). Deinstitutionalization and schizophrenia in Finland II; dischareged patients and their psychosocial functioning. Schizophrenia Bulletin, 25(3), 543–551.CrossRefPubMed Honkonen, T., Saarinen, S., & Salokangas, R.K. (1999). Deinstitutionalization and schizophrenia in Finland II; dischareged patients and their psychosocial functioning. Schizophrenia Bulletin, 25(3), 543–551.CrossRefPubMed
Zurück zum Zitat Shivashankar, S., Telfer, S., Arunagiriraj, J., McKinnon, M., Jauhar, S., Krishnadas, R., et al. (2013). Has the prevalence, clinical presentation and social functioning of schizophrenia changed over the last 25 years? Nithsdale schizophrenia survey revisited. Schizophrenia Research, 146(1–3):349–356.CrossRefPubMed Shivashankar, S., Telfer, S., Arunagiriraj, J., McKinnon, M., Jauhar, S., Krishnadas, R., et al. (2013). Has the prevalence, clinical presentation and social functioning of schizophrenia changed over the last 25 years? Nithsdale schizophrenia survey revisited. Schizophrenia Research, 146(1–3):349–356.CrossRefPubMed
Zurück zum Zitat Kanahara, N., Yoshida, T., Oda, Y., Yamanaka, H., Moriyama, T., Hayashi, H., et al. (2013). Onset pattern and long-term prognosis in schizophrenia: 10-Year longitudinal follow-up study. PLOS ONE,8(6), e67273. http://www.plosone.org. Kanahara, N., Yoshida, T., Oda, Y., Yamanaka, H., Moriyama, T., Hayashi, H., et al. (2013). Onset pattern and long-term prognosis in schizophrenia: 10-Year longitudinal follow-up study. PLOS ONE,8(6), e67273. http://​www.​plosone.​org.
Zurück zum Zitat Kay, S.R., Fiszbein, A., & Opler, L.A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13(2), 261–276.CrossRefPubMed Kay, S.R., Fiszbein, A., & Opler, L.A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13(2), 261–276.CrossRefPubMed
Zurück zum Zitat Kostakoğlu, A.E., Batur, S., Tiryaki, A., & Göğüş, A. (1999). Pozitifve Negatif Sendrom Ölçeğinin (PANSS) Türkçeuyarlamasınıngeçerlilikvegüvenilirliği. TürkPsikiyatriDergisi, 14, 23–32. Kostakoğlu, A.E., Batur, S., Tiryaki, A., & Göğüş, A. (1999). Pozitifve Negatif Sendrom Ölçeğinin (PANSS) Türkçeuyarlamasınıngeçerlilikvegüvenilirliği. TürkPsikiyatriDergisi, 14, 23–32.
Zurück zum Zitat Marshall, M., Husain, N., Bork, N., Chaudhry, I.B., Lester, H., Everard, L., et al. (2014). Impact of early intervention services on duration of untreated psychosis: Data from the national EDEN prospective cohort study. Schizophrenia Research, 159(1), 1–6.CrossRefPubMed Marshall, M., Husain, N., Bork, N., Chaudhry, I.B., Lester, H., Everard, L., et al. (2014). Impact of early intervention services on duration of untreated psychosis: Data from the national EDEN prospective cohort study. Schizophrenia Research, 159(1), 1–6.CrossRefPubMed
Zurück zum Zitat Marshall, M., Lewis, S., Lockwood, A., Drake, R., Jones, P., & Croudace, T. (2005). Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: A systematic review. Archives of General Psychiatry, 62(9), 975–983.CrossRefPubMed Marshall, M., Lewis, S., Lockwood, A., Drake, R., Jones, P., & Croudace, T. (2005). Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: A systematic review. Archives of General Psychiatry, 62(9), 975–983.CrossRefPubMed
Zurück zum Zitat McGorry, P.D., Killackey, E., & Yung, A. (2008). Early intervention in psychosis: Concepts, evidence and future directions. World Psychiatry, 7(3), 148–156.CrossRefPubMedPubMedCentral McGorry, P.D., Killackey, E., & Yung, A. (2008). Early intervention in psychosis: Concepts, evidence and future directions. World Psychiatry, 7(3), 148–156.CrossRefPubMedPubMedCentral
Zurück zum Zitat Mueser, K.T., Bond, Q.R., Drake, R.E., & Resnick, S.G. (1998). Models of community care for severe mental ıllness: A review of research on case management. Schizophrenia Bulletin, 24(1), 37–74.CrossRefPubMed Mueser, K.T., Bond, Q.R., Drake, R.E., & Resnick, S.G. (1998). Models of community care for severe mental ıllness: A review of research on case management. Schizophrenia Bulletin, 24(1), 37–74.CrossRefPubMed
Zurück zum Zitat O’Donoghue, B., Lyne, J., Kinsella, A., Turner, N., O’Callaghan, E., & Clarke, M. (2014). Detection and characteristics of individuals with a very long duration of untreated psychosis in an early intervention for psychosis service. Early Intervention in Psychiatry, 8(4), 332–339.CrossRefPubMed O’Donoghue, B., Lyne, J., Kinsella, A., Turner, N., O’Callaghan, E., & Clarke, M. (2014). Detection and characteristics of individuals with a very long duration of untreated psychosis in an early intervention for psychosis service. Early Intervention in Psychiatry, 8(4), 332–339.CrossRefPubMed
Zurück zum Zitat Perkins, D., Gu, H., Boteva, K., & Lieberman, J.A. (2005). Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: A critical review and meta-analysis. American Journal of Psychiatry, 162(10), 1785–1804.CrossRefPubMed Perkins, D., Gu, H., Boteva, K., & Lieberman, J.A. (2005). Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: A critical review and meta-analysis. American Journal of Psychiatry, 162(10), 1785–1804.CrossRefPubMed
Zurück zum Zitat Priebe, S., Fakhoury, W., White, I., Watts, J., Bebbington, P., Burns, T., et al. (2004). Characteristics of teams, staff and patients: Associations without comes of patients in assertive outreach. Pan-London assertive outreach study group. The British Journal of Psychiatry: The Journal of Mental Science, 185(4), 306–311.CrossRef Priebe, S., Fakhoury, W., White, I., Watts, J., Bebbington, P., Burns, T., et al. (2004). Characteristics of teams, staff and patients: Associations without comes of patients in assertive outreach. Pan-London assertive outreach study group. The British Journal of Psychiatry: The Journal of Mental Science, 185(4), 306–311.CrossRef
Zurück zum Zitat Primavera, D., Bandecch, C., Lepori, T., Sanna, L., Nicotra, E., & Carpiniello, B. (2012). Does duration of untreated psychosis predict very long term outcome of schizophrenic disorders? Results of a retrospective study. Annals of General Psychiatry, 11, 21.CrossRefPubMedPubMedCentral Primavera, D., Bandecch, C., Lepori, T., Sanna, L., Nicotra, E., & Carpiniello, B. (2012). Does duration of untreated psychosis predict very long term outcome of schizophrenic disorders? Results of a retrospective study. Annals of General Psychiatry, 11, 21.CrossRefPubMedPubMedCentral
Zurück zum Zitat Skeate, A., Jackson, C., Birchwood, M., & Jones, C. (2002). Duration of untreated psychosis and pathways to care in first-episode psychosis İnvestigation of help-seeking behaviour in primary care. British Journal of Psychiatry, 181, 73–77.CrossRef Skeate, A., Jackson, C., Birchwood, M., & Jones, C. (2002). Duration of untreated psychosis and pathways to care in first-episode psychosis İnvestigation of help-seeking behaviour in primary care. British Journal of Psychiatry, 181, 73–77.CrossRef
Zurück zum Zitat Soygür, H., Aybaş, M., Hınçal, G., & Aydemir, Ç. (2000). Şizofreni hastalarıiçinyaşamnitelikleriölçeği: Güvenirlikveyapısalgeçerlikçalışması. Düşünen Adam, 13, 204–210. Soygür, H., Aybaş, M., Hınçal, G., & Aydemir, Ç. (2000). Şizofreni hastalarıiçinyaşamnitelikleriölçeği: Güvenirlikveyapısalgeçerlikçalışması. Düşünen Adam, 13, 204–210.
Zurück zum Zitat Tandon, R., Nasrallah, H.A., & Keshavan, M.S. (2010). Schizophrenia, “Just the Facts” 5. Treatment and prevention past, present, and future. Schizophrenia Research, 122(1–3), 1–23.CrossRefPubMed Tandon, R., Nasrallah, H.A., & Keshavan, M.S. (2010). Schizophrenia, “Just the Facts” 5. Treatment and prevention past, present, and future. Schizophrenia Research, 122(1–3), 1–23.CrossRefPubMed
Zurück zum Zitat Tansella, M., & Thornıcroft, G. (2002). Balancing communıty –based and hospıtal-based mental health care. World Psychiatry, 1(2), 84–90.PubMedPubMedCentral Tansella, M., & Thornıcroft, G. (2002). Balancing communıty –based and hospıtal-based mental health care. World Psychiatry, 1(2), 84–90.PubMedPubMedCentral
Zurück zum Zitat Thornicorft, G., & Tansella, M. (2009). Better mental health care. Cambridge: Cambridge University Press, 141–145. Thornicorft, G., & Tansella, M. (2009). Better mental health care. Cambridge: Cambridge University Press, 141–145.
Zurück zum Zitat Thornicroft, G., & Tansella, M. (2004). Components of a modern mental health service: A pragmatic balance of community and hospital care : Overview of systematic evidence. The British Journal of Psychiatry, 185, 283–290.CrossRefPubMed Thornicroft, G., & Tansella, M. (2004). Components of a modern mental health service: A pragmatic balance of community and hospital care : Overview of systematic evidence. The British Journal of Psychiatry, 185, 283–290.CrossRefPubMed
Zurück zum Zitat Wanchek, T.N., McGarvey, E.L., Leon-Verdin, M., & Bonnie, R.J. (2011). The effect of community mental health services on hospitalization rates in Virginia. Psychiatric Services (Washington, D. C.), 62(2), 194–199.CrossRef Wanchek, T.N., McGarvey, E.L., Leon-Verdin, M., & Bonnie, R.J. (2011). The effect of community mental health services on hospitalization rates in Virginia. Psychiatric Services (Washington, D. C.), 62(2), 194–199.CrossRef
Zurück zum Zitat Yıldız M, Yazıcı A, Ünal S, Aker T, Özgen G, Ekmekçi H, ve ark. (2002). Şizofreninin ruhsal-toplumsal tedavisinde sosyal beceri eğitimi. Türk Psikiyatri Dergisi, 13(1), 41–47.PubMed Yıldız M, Yazıcı A, Ünal S, Aker T, Özgen G, Ekmekçi H, ve ark. (2002). Şizofreninin ruhsal-toplumsal tedavisinde sosyal beceri eğitimi. Türk Psikiyatri Dergisi, 13(1), 41–47.PubMed
Zurück zum Zitat Iqbal, N., Nkire, N., Nwachukwu, I., Young, C., & Russell, V. (2012). Home-based treatment and psychiatric admission rates: Experience of an adult community mental health service in Ireland. International Journal of Psychiatry in Clinical Practice, 16(4), 300–306.CrossRefPubMed Iqbal, N., Nkire, N., Nwachukwu, I., Young, C., & Russell, V. (2012). Home-based treatment and psychiatric admission rates: Experience of an adult community mental health service in Ireland. International Journal of Psychiatry in Clinical Practice, 16(4), 300–306.CrossRefPubMed
Metadaten
Titel
Longer Duration of Untreated Psychosis Hinders Improvement in Treatment of Chronic Schizophrenia: Community Based Early Intervention is an Evidence Based Option
verfasst von
Abdülkadir Tabo
Erkan Aydın
Hüseyin Yumrukçal
Sadık Yiğit
Uğraş Erman Uzun
Oğuz Karamustafalıoğlu
Publikationsdatum
10.02.2017
Verlag
Springer US
Erschienen in
Community Mental Health Journal / Ausgabe 8/2017
Print ISSN: 0010-3853
Elektronische ISSN: 1573-2789
DOI
https://doi.org/10.1007/s10597-017-0088-9

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