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Erschienen in: Social Psychiatry and Psychiatric Epidemiology 2/2017

28.12.2016 | Original Paper

Low incidence of psychosis in Italy: confirmation from the first epidemiological study in Sicily

verfasst von: A. Mulè, L. Sideli, V. Capuccio, P. Fearon, L. Ferraro, J. B. Kirkbride, C. La Cascia, C. Sartorio, F. Seminerio, G. Tripoli, M. Di Forti, D. La Barbera, R. M. Murray

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 2/2017

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Abstract

Purpose

The incidence of psychotic disorders varies in different geographical areas. As there have been no reports from Southern Italy, this study aimed to determine the incidence rate of first-episode psychosis in Palermo, Sicily.

Methods

All patients, aged 18–65 years, presenting with a first episode of psychosis (FEP) (ICD-10 F20–29, F30–33) to mental health services in Palermo, were recorded over a 3-year period. Incidence rates of psychotic disorders and their 95% confidence intervals (95% CI) were estimated. Poisson regression was applied to estimate the differences in incidence rate ratio (IRR) by age, sex and migrant status.

Results

Two hundred and four FEP participants were identified during the 3 years; 183 (89.7%, males n = 112) participants were native Italians and 21 were migrants (10.3%, males n = 14). The crude incidence of all psychoses was 15.9 (95% CI 13.7–18.1). As predicted, the risk of schizophrenia F20 was higher in males compared to females (adjusted IRR = 1.99, 95% CI 1.36–2.88) and in migrants compared to native Italians (adjusted IRR = 4.02, 95% CI 2.39–6.75).

Conclusions

This study, the first from Sicily, confirms previous findings from Northern Italy that the risk of schizophrenia and other psychoses is much lower in Italian cities than those reported from cities in Northern Europe; the reasons for this disparity may provide important clues to the aetiology of psychosis.
Literatur
1.
Zurück zum Zitat Jablensky A, Sartorius N, Ernberg G, Anker M, Korten A, Cooper JE et al (1992) Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychol Med Monogr Suppl 20:1–97CrossRefPubMed Jablensky A, Sartorius N, Ernberg G, Anker M, Korten A, Cooper JE et al (1992) Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychol Med Monogr Suppl 20:1–97CrossRefPubMed
2.
Zurück zum Zitat McGrath J, Saha S, Welham J, El Saadi O, MacCauley C, Chant D (2004) A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med 2:13CrossRefPubMedPubMedCentral McGrath J, Saha S, Welham J, El Saadi O, MacCauley C, Chant D (2004) A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med 2:13CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Oedegaard O (1946) A statistical investigation of the incidence of mental disorder in Norway. Psychiatr Q 20:381–399CrossRefPubMed Oedegaard O (1946) A statistical investigation of the incidence of mental disorder in Norway. Psychiatr Q 20:381–399CrossRefPubMed
4.
Zurück zum Zitat Munk-Jørgensen P, Mortensen PB (1992) Incidence and other aspects of the epidemiology of schizophrenia in Denmark, 1971–87. Br J Psychiatry 161:489–495CrossRefPubMed Munk-Jørgensen P, Mortensen PB (1992) Incidence and other aspects of the epidemiology of schizophrenia in Denmark, 1971–87. Br J Psychiatry 161:489–495CrossRefPubMed
5.
Zurück zum Zitat Scully PJ, Quinn JF, Morgan MG, Kinsella A, O’Callaghan E, Owens JM et al (2002) First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: incidence and gender in the Cavan-Monaghan study at 5 years. Br J Psychiatry Suppl 43:s3–s9CrossRefPubMed Scully PJ, Quinn JF, Morgan MG, Kinsella A, O’Callaghan E, Owens JM et al (2002) First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: incidence and gender in the Cavan-Monaghan study at 5 years. Br J Psychiatry Suppl 43:s3–s9CrossRefPubMed
6.
Zurück zum Zitat Kirkbride JB, Fearon P, Morgan C, Dazzan P, Morgan K, Tarrant J et al (2006) Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study. Arch Gen Psychiatry 63:250–258CrossRefPubMed Kirkbride JB, Fearon P, Morgan C, Dazzan P, Morgan K, Tarrant J et al (2006) Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study. Arch Gen Psychiatry 63:250–258CrossRefPubMed
7.
Zurück zum Zitat World Health Organization (1978) Mental Disorders: a glossary and guide to their classification in accordance with the ninth revision of the International Classification of Diseases. WHO, Geneva World Health Organization (1978) Mental Disorders: a glossary and guide to their classification in accordance with the ninth revision of the International Classification of Diseases. WHO, Geneva
8.
Zurück zum Zitat Tansella M, Balestrieri M, Meneghelli G, Micciolo R (1991) Trends in the provision of psychiatric care 1979–1988. Psychol Med Monogr Suppl 19:5CrossRef Tansella M, Balestrieri M, Meneghelli G, Micciolo R (1991) Trends in the provision of psychiatric care 1979–1988. Psychol Med Monogr Suppl 19:5CrossRef
9.
Zurück zum Zitat de Salvia D, Barbato A, Salvo P, Zadro F (1993) Prevalence and incidence of schizophrenic disorders in Portogruaro. An Italian case register study. J Nerv Ment Dis 181:275–282CrossRefPubMed de Salvia D, Barbato A, Salvo P, Zadro F (1993) Prevalence and incidence of schizophrenic disorders in Portogruaro. An Italian case register study. J Nerv Ment Dis 181:275–282CrossRefPubMed
10.
Zurück zum Zitat Preti A, Miotto P (2000) Increase in first admissions for schizophrenia and other major psychoses in Italy. Psychiatry Res 94:139–152CrossRefPubMed Preti A, Miotto P (2000) Increase in first admissions for schizophrenia and other major psychoses in Italy. Psychiatry Res 94:139–152CrossRefPubMed
12.
Zurück zum Zitat World Health Organization (1992) The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. World Health Organization, Geneva World Health Organization (1992) The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. World Health Organization, Geneva
13.
Zurück zum Zitat Tarricone I, Mimmi S, Paparelli A, Rossi E, Mori E, Panigada S et al (2012) First-episode psychosis at the West Bologna Community Mental Health Centre: results of an 8-year prospective study. Psychol Med 42:2255–2264CrossRefPubMed Tarricone I, Mimmi S, Paparelli A, Rossi E, Mori E, Panigada S et al (2012) First-episode psychosis at the West Bologna Community Mental Health Centre: results of an 8-year prospective study. Psychol Med 42:2255–2264CrossRefPubMed
14.
Zurück zum Zitat Lasalvia A, Bonetto C, Tosato S, Zanatta G, Cristofalo D, Salazzari D et al (2014) First-contact incidence of psychosis in north-eastern Italy: influence of age, gender, immigration and socioeconomic deprivation. Br J Psychiatry 205:127–134CrossRefPubMed Lasalvia A, Bonetto C, Tosato S, Zanatta G, Cristofalo D, Salazzari D et al (2014) First-contact incidence of psychosis in north-eastern Italy: influence of age, gender, immigration and socioeconomic deprivation. Br J Psychiatry 205:127–134CrossRefPubMed
16.
Zurück zum Zitat Sistema Statistico Nazionale. Istituto Nazionale di Statistica (ISTAT) (2011) 15° Censimento generale della popolazione e delle abitazioni. Struttura demografica della popolazione. Dati definitivi Sistema Statistico Nazionale. Istituto Nazionale di Statistica (ISTAT) (2011) 15° Censimento generale della popolazione e delle abitazioni. Struttura demografica della popolazione. Dati definitivi
17.
Zurück zum Zitat Fearon P, Kirkbride JB, Morgan C, Dazzan P, Morgan K, Lloyd T et al (2006) Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study. Psychol Med 36:1541–1550CrossRefPubMed Fearon P, Kirkbride JB, Morgan C, Dazzan P, Morgan K, Lloyd T et al (2006) Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study. Psychol Med 36:1541–1550CrossRefPubMed
19.
Zurück zum Zitat Gazzetta Ufficiale della Repubblica Italiana no. 72 Gazzetta Ufficiale della Repubblica Italiana no. 72
20.
Zurück zum Zitat World Health Organization (1992) Schedules for clinical assessment in neuropsychiatry (SCAN). World Health Organization, Geneva World Health Organization (1992) Schedules for clinical assessment in neuropsychiatry (SCAN). World Health Organization, Geneva
21.
Zurück zum Zitat Mallett R (1997) Sociodemographic schedule. Section of Social Psychiatry, Institute of Psychiatry, London Mallett R (1997) Sociodemographic schedule. Section of Social Psychiatry, Institute of Psychiatry, London
22.
Zurück zum Zitat World Health Organization (1993) The ICD-10 classification of mental and behavioural disorders-diagnostic criteria for research. World Health Organization, Geneva World Health Organization (1993) The ICD-10 classification of mental and behavioural disorders-diagnostic criteria for research. World Health Organization, Geneva
23.
Zurück zum Zitat Castle DJ, Sham PC, Wessely S, Murray RM (1994) The subtyping of schizophrenia in men and women: a latent class analysis. Psychol Med 24:41–51CrossRefPubMed Castle DJ, Sham PC, Wessely S, Murray RM (1994) The subtyping of schizophrenia in men and women: a latent class analysis. Psychol Med 24:41–51CrossRefPubMed
24.
Zurück zum Zitat Häfner H, Riecher-Rössler A, An Der Heiden W, Maurer K, Fätkenheuer B, Löffler W (1993) Generating and testing a causal explanation of the gender difference in age at first onset of schizophrenia. Psychol Med 23:925–940CrossRefPubMed Häfner H, Riecher-Rössler A, An Der Heiden W, Maurer K, Fätkenheuer B, Löffler W (1993) Generating and testing a causal explanation of the gender difference in age at first onset of schizophrenia. Psychol Med 23:925–940CrossRefPubMed
25.
Zurück zum Zitat Nasser EH, Walders N, Jenkins JH (2002) The experience of schizophrenia: what’s gender got to do with it? A critical review of the current status of research on schizophrenia. Schizophr Bull 28:351–362CrossRefPubMed Nasser EH, Walders N, Jenkins JH (2002) The experience of schizophrenia: what’s gender got to do with it? A critical review of the current status of research on schizophrenia. Schizophr Bull 28:351–362CrossRefPubMed
26.
Zurück zum Zitat Tarricone I, Stivanello E, Ferrari S, Colombini N, Bolla E, Braca M et al (2012) Migrant pathways to community mental health centres in Italy. Int J Soc Psychiatry 58:505–511CrossRefPubMed Tarricone I, Stivanello E, Ferrari S, Colombini N, Bolla E, Braca M et al (2012) Migrant pathways to community mental health centres in Italy. Int J Soc Psychiatry 58:505–511CrossRefPubMed
27.
Zurück zum Zitat Sistema Statistico Nazionale. Istituto Nazionale di Statistica (ISTAT) (2015). The post enumeration survey (PES) of the 15th Italian population census Sistema Statistico Nazionale. Istituto Nazionale di Statistica (ISTAT) (2015). The post enumeration survey (PES) of the 15th Italian population census
28.
Zurück zum Zitat Morgan C, Kirkbride J, Hutchinson G, Craig T, Morgan K, Dazzan P et al (2008) Cumulative social disadvantage, ethnicity and first-episode psychosis: a case-control study. Psychol Med 38:1701–1715CrossRefPubMed Morgan C, Kirkbride J, Hutchinson G, Craig T, Morgan K, Dazzan P et al (2008) Cumulative social disadvantage, ethnicity and first-episode psychosis: a case-control study. Psychol Med 38:1701–1715CrossRefPubMed
Metadaten
Titel
Low incidence of psychosis in Italy: confirmation from the first epidemiological study in Sicily
verfasst von
A. Mulè
L. Sideli
V. Capuccio
P. Fearon
L. Ferraro
J. B. Kirkbride
C. La Cascia
C. Sartorio
F. Seminerio
G. Tripoli
M. Di Forti
D. La Barbera
R. M. Murray
Publikationsdatum
28.12.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 2/2017
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-016-1322-4

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