Erschienen in:
03.10.2017 | Research Letter
Lower corneal nerve fibre length identifies diabetic neuropathy in older adults with diabetes: results from the Canadian Study of Longevity in Type 1 Diabetes
verfasst von:
Daniel Scarr, Leif E. Lovblom, Julie A. Lovshin, Geneviève Boulet, Mohammed A. Farooqi, Andrej Orszag, Alanna Weisman, Nancy Cardinez, Yuliya Lytvyn, Mylan Ngo, Hillary A. Keenan, Michael H. Brent, Narinder Paul, Vera Bril, David Z. I. Cherney, Bruce A. Perkins
Erschienen in:
Diabetologia
|
Ausgabe 12/2017
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Excerpt
To the Editor: There exists an urgent need to better characterise and identify the presence of early-stage diabetic neuropathy when therapy is most likely to be effective. The lack of an objective endpoint for early neuropathy has seriously hindered the evaluation of disease-modifying therapies in clinical research and the prediction of neuropathy progression in clinical care [
1,
2]. There is considerable evidence that injury to small, thinly myelinated and unmyelinated nerve fibres precedes injury to large myelinated fibres in individuals with diabetic neuropathy [
3]. …