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10.01.2022 | Original Paper

Lower serum levels of vitamin D in adults with urinary tract infection

verfasst von: Lingling Liu, Kehang Xie, Mengmeng Yin, Xiaoqiu Chen, Binhuan Chen, Jianting Ke, Cheng Wang

Erschienen in: Infection | Ausgabe 3/2022

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Abstract

Purpose

We aimed to explore the association between urinary tract infection (UTI) in adults and serum 25-hydroxyvitamin D (25OHD), which was used to access vitamin D status.

Methods

Serum levels of 25OHD were retrospectively analyzed in 234 subjects (190 females and 44 males): 120 UTI patients (females = 103) and 114 age- and sex-matched healthy controls (females = 87). Serum 25OHD concentrations were categorized as follows: (1) < 20 ng/mL, 20 to < 30 ng/mL, and ≥ 30 ng/mL; (2) < 20 ng/mL and ≥ 20 ng/mL.

Results

Serum 25OHD levels were lower in patients with UTI (p < 0.01). Women with UTI presented significantly lower 25OHD concentrations than those without UTI (p < 0.01). No association between serum 25OHD levels and UTI in men was found (p > 0.05). The multivariable logistic regression models showed significant associations between UTI and 25OHD, female sex, neutrophilic lymphocyte ratio and C-reactive protein (p < 0.05).

Conclusion

Lower 25OHD concentrations associated with UTI were most prominent among women. The associations between UTI and low serum 25OHD levels as well as female sex were independent of each other.

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Titel: Lower serum levels of vitamin D in adults with urinary tract infection
verfasst von: Lingling Liu
Kehang Xie
Mengmeng Yin
Xiaoqiu Chen
Binhuan Chen
Jianting Ke
Cheng Wang
Publikationsdatum: 10.01.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Infection / Ausgabe 3/2022
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-021-01750-2

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Lower serum levels of vitamin D in adults with urinary tract infection