27.01.2022 | Research article
Lucillia Sericata larval therapy in the treatment of diabetic chronic wounds
verfasst von:
Arash Jafari, Seyed Vahid Hosseini, Hossein Javaheri Hemmat, Hajar Khazraei
Erschienen in:
Journal of Diabetes & Metabolic Disorders
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Ausgabe 1/2022
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Abstract
Purpose
Wounds with dead tissue, purulent wounds, and gangrene are good options for larval therapy. We aim to investigate the effect of larval therapy on diabetic wounds and compare it with traditional treatment.
Methods
The sterile larvae were used in wound treatment and the infection rate, Erythrocyte Sedimentation Rate (ESR), and wound size were measured and compared before and after the treatment.
Results
The scars of 40 patients in the larval therapy group were evaluated every 10 days and the mean size of the scar decreased from 38.5 cm (36.6 cm) before treatment to 5.0 cm (6.6 cm) after 60 days. ESR mean was decreased from 57.3 (18.3) before treatment to 15.8 (4.8) after treatment in the larval therapy group. These parameters were significantly decreased compared to the debridement group (p < 0.001).
Conclusions
Larval therapy is effective in diabetic wound healing. The size of the wound after larval treatment is smaller than before. There was no difference between the two groups for infection rate. ESR was significantly decreased in the larval therapy group that indicating the lower inflammation in this group.