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Erschienen in: Critical Care 4/2010

01.08.2010 | Letter

Lung reaeration after surfactant instillation - caused by surfactant or caused by instillation?

verfasst von: Marcus J Schultz

Erschienen in: Critical Care | Ausgabe 4/2010

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Excerpt

In this issue of Critical Care, Lu and colleagues [1] report significant and prolonged lung reaeration after intratracheal bolus instillation of porcine-derived surfactant. In this substudy of a larger randomized controlled trial of patients with acute lung injury [2], the investigators elegantly demonstrate increased volumes of gas in poorly and non-aerated lung of patients who were treated with surfactant as compared with patients who received routine care. …
Literatur
1.
Zurück zum Zitat Lu Q, Zhang M, Girardi C, Bouhemad B, Kesecioglu J, Rouby JJ: Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury. Crit Care 2010, 14: R135. 10.1186/cc9186PubMedCentralCrossRefPubMed Lu Q, Zhang M, Girardi C, Bouhemad B, Kesecioglu J, Rouby JJ: Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury. Crit Care 2010, 14: R135. 10.1186/cc9186PubMedCentralCrossRefPubMed
2.
Zurück zum Zitat Kesecioglu J, Beale R, Stewart TE, Findlay GP, Rouby JJ, Holzapfel L, Bruins P, Steenken EJ, Jeppesen OK, Lachmann B: Exogenous natural surfactant for treatment of acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2009, 180: 989-994. 10.1164/rccm.200812-1955OCCrossRefPubMed Kesecioglu J, Beale R, Stewart TE, Findlay GP, Rouby JJ, Holzapfel L, Bruins P, Steenken EJ, Jeppesen OK, Lachmann B: Exogenous natural surfactant for treatment of acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2009, 180: 989-994. 10.1164/rccm.200812-1955OCCrossRefPubMed
3.
Zurück zum Zitat Oczenski W, Hormann C, Keller C, Lorenzl N, Kepka A, Schwarz S, Fitzgerald RD: Recruitment maneuvers after a positive end-expiratory pressure trial do not induce sustained effects in early adult respiratory distress syndrome. Anesthesiology 2004, 101: 620-625. 10.1097/00000542-200409000-00010CrossRefPubMed Oczenski W, Hormann C, Keller C, Lorenzl N, Kepka A, Schwarz S, Fitzgerald RD: Recruitment maneuvers after a positive end-expiratory pressure trial do not induce sustained effects in early adult respiratory distress syndrome. Anesthesiology 2004, 101: 620-625. 10.1097/00000542-200409000-00010CrossRefPubMed
Metadaten
Titel
Lung reaeration after surfactant instillation - caused by surfactant or caused by instillation?
verfasst von
Marcus J Schultz
Publikationsdatum
01.08.2010
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 4/2010
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9211

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