Erschienen in:
19.12.2018 | Brief Report
Lung transplantation in two cystic fibrosis patients infected with previously pandrug-resistant Burkholderia cepacia complex treated with ceftazidime–avibactam
verfasst von:
Ibai Los-Arcos, Oscar Len, María Teresa Martín-Gómez, Juan José González-López, Berta Saéz-Giménez, María Deu, Xavier Nuvials, Ricard Ferrer, Antonio Román, Joan Gavaldà
Erschienen in:
Infection
|
Ausgabe 2/2019
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Abstract
We describe two cystic fibrosis patients infected with pandrug-resistant Burkholderia cepacia complex, with the exception of ceftazidime–avibactam, who received prophylaxis with this antibiotic during lung transplantation. Although both patients had a post-operative relapse of respiratory infection, one with positive blood cultures, ceftazidime–avibactam treatment yielded a favourable outcome. 12 months after transplantation, one patient presented an excellent clinical outcome. However, the other patient died 10 months later due to severe B. cepacia sinusitis with intracranial invasion.