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Erschienen in: Neurocritical Care 2/2011

01.10.2011 | Review

Magnesium Sulfate Administration in Subarachnoid Hemorrhage

verfasst von: Jose I. Suarez, The Participants in the International Multidisciplinary Consensus Conference on the Critical Care Management of Subarachnoid Hemorrhage

Erschienen in: Neurocritical Care | Ausgabe 2/2011

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Abstract

Magnesium offers theoretic vascular and neuroprotective benefits for patients with subarachnoid hemorrhage. An electronic literature search was conducted to identify original research studies describing intravenous magnesium treatment in patients with SAH published in English between January 1990 and October 2010. Seventeen articles were identified and reviewed, including one phase III randomized-controlled clinical trial and six phase II randomized-controlled trials. Study quality was low for most of the included studies, with the phase III trial considered to be of moderate quality. Due to inconsistently reported benefits and the occurrence of side effects, phase II data suggested that intravenous magnesium for SAH provided either no overall net benefit or uncertain trade-offs. Benefit was likewise not supported in the single phase III clinical trial.
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Metadaten
Titel
Magnesium Sulfate Administration in Subarachnoid Hemorrhage
verfasst von
Jose I. Suarez
The Participants in the International Multidisciplinary Consensus Conference on the Critical Care Management of Subarachnoid Hemorrhage
Publikationsdatum
01.10.2011
Verlag
Humana Press Inc
Erschienen in
Neurocritical Care / Ausgabe 2/2011
Print ISSN: 1541-6933
Elektronische ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-011-9603-y

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