nach oben

Pediatric Radiology

Erschienen in:

01.12.2020 | Fetal imaging

Magnetic resonance imaging of the fetal musculoskeletal system

verfasst von: Nancy A. Chauvin, Teresa Victoria, Asef Khwaja, Hisham Dahmoush, Diego Jaramillo

Erschienen in: Pediatric Radiology | Ausgabe 13/2020

Einloggen, um Zugang zu erhalten

Abstract

Diagnosing musculoskeletal pathology requires understanding of the normal embryological development. Intrinsic errors of skeletal development are individually rare but are of paramount clinical importance because anomalies can greatly impact patients’ lives. An accurate assessment of the fetal musculoskeletal system must be performed to provide optimal genetic counseling as well as to drive therapeutic management. This manuscript reviews the embryology of skeletal development and the appearance of the maturing musculoskeletal system on fetal MRI. In addition, it presents a comprehensive review of musculoskeletal fetal pathology along with postnatal imaging.

Nur mit Berechtigung zugänglich

Nemec SF, Nemec U, Brugger PC et al (2012) MR imaging of the fetal musculoskeletal system. Prenat Diagn 32:205–213PubMedCrossRef

Neuman J, Calvo-Garcia MA, Kline-Fath BM et al (2012) Prenatal imaging of amniotic band sequence: utility and role of fetal MRI as an adjunct to prenatal US. Pediatr Radiol 42:544–551PubMedCrossRef

Nemec SF, Kasprian G, Brugger PC et al (2011) Abnormalities of the upper extremities on fetal magnetic resonance imaging. Ultrasound Obstet Gynecol 38:559–567PubMedCrossRef

Laor T, Jaramillo D (2009) MR imaging insights into skeletal maturation: what is normal? Radiology 250:28–38PubMedCrossRef

Nemec SF, Nemec U, Brugger PC et al (2011) Skeletal development on fetal magnetic resonance imaging. Top Magn Reson Imaging 22:101–106PubMedCrossRef

Kovacs CS (2011) Bone development in the fetus and neonate: role of the calciotropic hormones. Curr Osteoporos Rep 9:274–283PubMedCrossRef

Laor T, Jaramillo D (2020) It's time to recognize the perichondrium. Pediatr Radiol 50:153–160PubMedCrossRef

Schumacher R, Seaver LH, Spranger J (2010) Fetal radiology a diagnostic atlas, 2nd edn. Springer-Verlag, HeidelbergCrossRef

Victoria T, Johnson AM, Edgar JC et al (2016) Comparison between 1.5-T and 3-T MRI for fetal imaging: is there an advantage to imaging with a higher field strength? AJR Am J Roentgenol 206:195–201PubMed

10.

Lyons K, Cassady C, Mehollin-Ray A, Krishnamurthy R (2015) Current role of fetal magnetic resonance imaging in body anomalies. Semin Ultrasound CT MR 36:310–323PubMedCrossRef

11.

Nemec U, Nemec SF, Krakow D et al (2011) The skeleton and musculature on foetal MRI. Insights Imag 2:309–318CrossRef

12.

Patel MD, Swinford AE, Filly RA (1994) Anatomic and sonographic features of the fetal skull. J Ultrasound Med 13:251–257PubMedCrossRef

13.

Rubio EI, Blask A, Bulas DI (2016) Ultrasound and MR imaging findings in prenatal diagnosis of craniosynostosis syndromes. Pediatr Radiol 46:709–718PubMedCrossRef

14.

Ketwaroo PD, Robson CD, Estroff JA (2015) Prenatal imaging of craniosynostosis syndromes. Semin Ultrasound CT MR 36:453–464PubMedCrossRef

15.

Werner H, Castro P, Daltro P et al (2018) Prenatal diagnosis of Apert syndrome using ultrasound, magnetic resonance imaging, and three-dimensional virtual/physical models: three case series and literature review. Childs Nerv Syst 34:1563–1571PubMedCrossRef

16.

Giancotti A, D'Ambrosio V, De Filippis A et al (2014) Comparison of ultrasound and magnetic resonance imaging in the prenatal diagnosis of Apert syndrome: report of a case. Childs Nerv Syst 30:1445–1448PubMed

17.

Mailath-Pokorny M, Klein K, Worda C et al (2012) Maxillary dental arch biometry: assessment with fetal MR imaging. Prenat Diagn 32:530–535PubMedCrossRef

18.

Nemec U, Nemec SF, Brugger PC et al (2015) Normal mandibular growth and diagnosis of micrognathia at prenatal MRI. Prenat Diagn 35:108–116PubMedCrossRef

19.

Wang G, Shan R, Zhao L et al (2011) Fetal cleft lip with and without cleft palate: comparison between MR imaging and US for prenatal diagnosis. Eur J Radiol 79:437–442PubMedCrossRef

20.

Resnick CM, Estroff JA, Kooiman TD et al (2018) Pathogenesis of cleft palate in Robin sequence: observations from prenatal magnetic resonance imaging. J Oral Maxillofac Surg 76:1058–1064PubMedCrossRef

21.

Rogers-Vizena CR, Mulliken JB, Daniels KM, Estroff JA (2016) Prenatal features predictive of Robin sequence identified by fetal magnetic resonance imaging. Plast Reconstr Surg 137:999e–1006ePubMedCrossRef

22.

Antonakopoulos N, Bhide A (2019) Focus on prenatal detection of micrognathia. J Fetal Med 6:107–112CrossRef

23.

Upasani VV, Ketwaroo PD, Estroff JA et al (2016) Prenatal diagnosis and assessment of congenital spinal anomalies: review for prenatal counseling. World J Orthop 7:406–417PubMedPubMedCentralCrossRef

24.

Yazici Z, Kline-Fath BM, Laor T, Tinkle BT (2010) Fetal MR imaging of Kniest dysplasia. Pediatr Radiol 40:348–352PubMedCrossRef

25.

Shekdar K (2016) MRI of fetal spine and extremities. In: Masselli G (ed) MRI of fetal and maternal diseases in pregnancy. Springer International Publishing, Switzerland, pp 139–158CrossRef

26.

Mekonen HK, Hikspoors JP, Mommen G et al (2015) Development of the ventral body wall in the human embryo. J Anat 227:673–685PubMedPubMedCentralCrossRef

27.

Dighe M, Fligner C, Cheng E et al (2008) Fetal skeletal dysplasia: an approach to diagnosis with illustrative cases. Radiographics 28:1061–1077PubMedCrossRef

28.

Victoria T, Epelman M, Coleman BG et al (2013) Low-dose fetal CT in the prenatal evaluation of skeletal dysplasias and other severe skeletal abnormalities. AJR Am J Roentgenol 200:989–1000PubMedCrossRef

29.

Donne HD Jr, Faundes A, Tristao EG et al (2005) Sonographic identification and measurement of the epiphyseal ossification centers as markers of fetal gestational age. J Clin Ultrasound 33:394–400PubMedCrossRef

30.

Gentili P, Trasimeni A, Giorlandino C (1984) Fetal ossification centers as predictors of gestational age in normal and abnormal pregnancies. J Ultrasound Med 3:193–197PubMedCrossRef

31.

Nemec U, Nemec SF, Weber M et al (2013) Human long bone development in vivo: analysis of the distal femoral epimetaphysis on MR images of fetuses. Radiology 267:570–580PubMedCrossRef

32.

Al-Qattan MM, Yang Y, Kozin SH (2009) Embryology of the upper limb. J Hand Surg Am 34:1340–1350PubMedCrossRef

33.

Alrabai HM, Farr A, Bettelheim D et al (2017) Prenatal diagnosis of congenital upper limb differences: a current concept review. J Matern Fetal Neonatal Med 30:2557–2563PubMedCrossRef

34.

Rosano A, Botto LD, Olney RS et al (2000) Limb defects associated with major congenital anomalies: clinical and epidemiological study from the International Clearinghouse for Birth Defects Monitoring Systems. Am J Med Genet 93:110–116PubMedCrossRef

35.

Sifakis S, Basel D, Ianakiev P et al (2001) Distal limb malformations: underlying mechanisms and clinical associations. Clin Genet 60:165–172PubMedCrossRef

36.

Barry M (2005) Prenatal assessment of foot deformity. Early Hum Dev 81:793–796PubMedCrossRef

37.

Dobbs MB, Gurnett CA (2009) Update on clubfoot: etiology and treatment. Clin Orthop Relat Res 467:1146–1153PubMedPubMedCentralCrossRef

38.

Servaes S, Hernandez A, Gonzalez L et al (2010) Fetal MRI of clubfoot associated with myelomeningocele. Pediatr Radiol 40:1874–1879PubMedCrossRef

39.

Nemec U, Nemec SF, Kasprian G et al (2012) Clubfeet and associated abnormalities on fetal magnetic resonance imaging. Prenat Diagn 32:822–828PubMed

40.

Miller M, Dobbs MB (2015) Congenital vertical talus: etiology and management. J Am Acad Orthop Surg 23:604–611PubMedCrossRef

41.

Rubio EI, Mehta N, Blask AR, Bulas DI (2017) Prenatal congenital vertical talus (rocker bottom foot): a marker for multisystem anomalies. Pediatr Radiol 47:1793–1799PubMedCrossRef

42.

Efkarpidis S, Alexopoulos E, Kean L et al (2004) Case-control study of factors associated with intrauterine fetal deaths. MedGenMed 6:53PubMedPubMedCentral

43.

Verbruggen SW, Loo JH, Hayat TT et al (2016) Modeling the biomechanics of fetal movements. Biomech Model Mechanobiol 15:995–1004PubMedCrossRef

44.

Guo WY, Ono S, Oi S et al (2006) Dynamic motion analysis of fetuses with central nervous system disorders by cine magnetic resonance imaging using fast imaging employing steady-state acquisition and parallel imaging: a preliminary result. J Neurosurg 105:94–100PubMed

45.

Krakow D, Lachman RS, Rimoin DL (2009) Guidelines for the prenatal diagnosis of fetal skeletal dysplasias. Genet Med 11:127–133PubMedPubMedCentralCrossRef

46.

Victoria T, Zhu X, Lachman R et al (2018) What is new in prenatal skeletal dysplasias? AJR Am J Roentgenol 210:1022–1033PubMedCrossRef

47.

Gilligan LA, Calvo-Garcia MA, Weaver KN, Kline-Fath BM (2020) Fetal magnetic resonance imaging of skeletal dysplasias. Pediatr Radiol 50:224–233PubMedCrossRef

48.

Berceanu C, Gheonea IA, Vladareanu S et al (2017) Ultrasound and MRI comprehensive approach in prenatal diagnosis of fetal osteochondrodysplasias. Cases series. Med Ultrason 19:66–72PubMedCrossRef

49.

Weaver KN, Johnson J, Kline-Fath B et al (2014) Predictive value of fetal lung volume in prenatally diagnosed skeletal dysplasia. Prenat Diagn 34:1326–1331PubMedCrossRef

Titel: Magnetic resonance imaging of the fetal musculoskeletal system
verfasst von: Nancy A. Chauvin
Teresa Victoria
Asef Khwaja
Hisham Dahmoush
Diego Jaramillo
Publikationsdatum: 01.12.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Radiology / Ausgabe 13/2020
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-020-04769-z

Neu im Fachgebiet Radiologie

18.04.2024 | Pädiatrische Notfallmedizin | Nachrichten

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Magnetic resonance imaging of the fetal musculoskeletal system

Abstract

Neu im Fachgebiet Radiologie

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

Wie toxische Männlichkeit der Gesundheit von Männern schadet

Studie bestätigt Potenzial von KI in der Radiologie

Update Radiologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 13/2020

Imaging phenotype correlation with molecular and molecular pathway defects in malformations of cortical development

Imaging of fetal cystic kidney disease: multicystic dysplastic kidney versus renal cystic dysplasia

Imaging of fetal ventriculomegaly

Imaging of open spinal dysraphisms in the era of prenatal surgery

The key role of the pediatric radiologist in developing a multidisciplinary fetal center

The impact of our images: psychological implications in expectant parents after a prenatal diagnosis

Neu im Fachgebiet Radiologie

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

Wie toxische Männlichkeit der Gesundheit von Männern schadet

Studie bestätigt Potenzial von KI in der Radiologie

Update Radiologie