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02.01.2020 | Review Article

Maintenance treatment in metastatic colorectal cancer: in search of the best strategy

verfasst von: D. A. Ron, R. Vera, C. M. Labandeira, M. C. Areses Manrique, M. Á. Núñez, N. G. Cid, J. G. Mata, A. F. Montes

Erschienen in: Clinical and Translational Oncology | Ausgabe 8/2020

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Abstract

Over the last 2 decades, the standard fluoropyrimidine-based chemotherapy backbone for metastatic colorectal cancer has been complemented by the addition of novel biological agents, achieving impressive increases in 5-year survival rates. Nonetheless, these new combinations have also entailed increases in toxicity, leading to evaluation of de-escalated chemotherapy regimens and "drug holiday" periods in attempts to reduce side effects and optimise quality of life without impairing efficacy. Here, we review the current and emerging evidence for maintenance schedules with chemotherapy and targeted agents, versus continuous treatment after induction treatment, in metastatic colorectal cancer patients.

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Titel: Maintenance treatment in metastatic colorectal cancer: in search of the best strategy
verfasst von: D. A. Ron
R. Vera
C. M. Labandeira
M. C. Areses Manrique
M. Á. Núñez
N. G. Cid
J. G. Mata
A. F. Montes
Publikationsdatum: 02.01.2020
Verlag: Springer International Publishing
Erschienen in: Clinical and Translational Oncology / Ausgabe 8/2020
Print ISSN: 1699-048X
Elektronische ISSN: 1699-3055
DOI: https://doi.org/10.1007/s12094-019-02267-9

Neu im Fachgebiet Onkologie

24.04.2024 | DGIM 2024 | Nachrichten

Springer Medizin

Maintenance treatment in metastatic colorectal cancer: in search of the best strategy

Abstract

Neu im Fachgebiet Onkologie

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Krebspatienten impfen: Was? Wen? Und wann nicht?

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Update Onkologie

Springer Medizin

Abstract

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