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Erschienen in: Die Ophthalmologie 9/2020

07.08.2020 | Makuladegeneration | Leitthema

Therapie subretinaler Makulablutungen

Was, wann, wie?

verfasst von: Prof. Dr. Lars‑Olof Hattenbach, F.E.B.O., Salvatore Grisanti, Nicolas Feltgen, Argyrios Chronopoulos

Erschienen in: Die Ophthalmologie | Ausgabe 9/2020

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Zusammenfassung

Hintergrund

Subretinale Blutungen im Bereich der Makula sind eine typische Komplikation verschiedener retinaler Erkrankungen, wobei die exsudative altersbedingte Makuladegeneration (AMD) die bei Weitem häufigste Ursache darstellt.

Methoden

Es erfolgte eine Literaturrecherche über PubMed.

Ergebnisse

Zahlreiche Studien zur Behandlung submakulärer Blutungen zeigen, dass eine erfolgreiche morphologische und funktionelle Behandlung mit unterschiedlichen Ansätzen wie der intravitrealen Gabe von VEGF(„vascular endothelial growth factor“)-Inhibitoren, der durch Fibrinolytika unterstützten pneumatischen Dislokation oder der chirurgischen Drainage möglich ist.

Diskussion

Aus den vorliegenden Daten kann bis heute kein genereller evidenzbasierter Therapiestandard abgeleitet werden, wobei sich ein zunehmender Trend zur Anwendung minimal-invasiver Verfahren abzeichnet. Unabhängig von der Wahl des initialen Therapieverfahrens sind eine möglichst frühzeitige Intervention sowie eine begleitende intravitreale Behandlung mit VEGF-Inhibitoren für das funktionelle Ergebnis entscheidend.
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Metadaten
Titel
Therapie subretinaler Makulablutungen
Was, wann, wie?
verfasst von
Prof. Dr. Lars‑Olof Hattenbach, F.E.B.O.
Salvatore Grisanti
Nicolas Feltgen
Argyrios Chronopoulos
Publikationsdatum
07.08.2020
Verlag
Springer Medizin
Erschienen in
Die Ophthalmologie / Ausgabe 9/2020
Print ISSN: 2731-720X
Elektronische ISSN: 2731-7218
DOI
https://doi.org/10.1007/s00347-020-01192-5

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