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Erschienen in: Neurological Sciences 8/2021

27.11.2020 | Original Article

Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response

verfasst von: Rui Li, Cong Li, Zhifeng Mao, Qiao Huang, Yaqing Shu, Yanyu Chang, Jingqi Wang, Yuge Wang, Wei Qiu

Erschienen in: Neurological Sciences | Ausgabe 8/2021

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Abstract

Background

Clinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date.

Objective

To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients.

Methods

We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD.

Results

We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients.

Conclusion

Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.
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Metadaten
Titel
Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response
verfasst von
Rui Li
Cong Li
Zhifeng Mao
Qiao Huang
Yaqing Shu
Yanyu Chang
Jingqi Wang
Yuge Wang
Wei Qiu
Publikationsdatum
27.11.2020
Verlag
Springer International Publishing
Erschienen in
Neurological Sciences / Ausgabe 8/2021
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-020-04933-1

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