Erschienen in:
01.09.2012 | Case Report
Malignant Gastrocolic Fistula as a Late Complication of Radiation Therapy
verfasst von:
Joan Costelloe, Clare O’Connell, Orla Mc Cormack, Finbar MacCarthy, Darragh F. Halpenny, Ramadan Shatwan, Cian Muldoon, Narayanasamy Ravi, John V. Reynolds
Erschienen in:
Journal of Gastrointestinal Cancer
|
Sonderheft 1/2012
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Excerpt
Malignant gastrocolic fistula is a rare mode of presentation of gastric or colonic carcinoma [
1‐
3]. A benign aetiology is more common, including peptic ulcer disease, particularly benign gastric ulcers which may relate to non-steroidal anti-inflammatory use. Other benign causes include inflammatory bowel disease, post-PEG insertion, post-gastroenterostomy, pancreatitis, abdominal tuberculosis, trauma, perforated diverticular disease and infections including CMV, histoplasmosis, actinomycosis, amoebiasis, echinococcosis and lymphogranuloma venereum [
2,
4‐
7]. A malignant gastrocolic fistula is most commonly found between the greater curvature of the stomach and the distal half of the transverse colon [
8]. They are usually seen in the setting of large infiltrative tumours with a surrounding inflammatory reaction, and lymph node involvement is uncommon [
8]. The colon rather than the stomach is the more usual site of origin. In a review of 1,500 cases of stomach cancer and 3,200 cases of colon cancer at the Lahey Clinic, 11 cases of gastrocolic fistula were reported, with 10 being of colonic origin [
9]. …