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Quality of Life Research

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01.11.2008

Mapping the eight-item Parkinson’s Disease Questionnaire (PDQ-8) to the EQ-5D utility index

verfasst von: Y. B. Cheung, L. C. S. Tan, P. N. Lau, W. L. Au, N. Luo

Erschienen in: Quality of Life Research | Ausgabe 9/2008

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Abstract

Objective

To develop a function for mapping the eight-item Parkinson’s Disease Questionnaire (PDQ-8) to the EuroQol Group’s EQ-5D utility index.

Methods

Data from two surveys of 324 patients with Parkinson’s disease was divided into two groups. One was used to estimate the mapping functions by regression methods and the other was used to validate the mapping functions.

Results

A regression model with a non-linear trend explained 55% of the variation in EQ-5D utility values and had a mean absolute deviation (MAD) of 0.083. A regression model assuming a linear trend explained 52% of the variation and had an MAD of 0.085. In the validation sample, predicted values based on the aforementioned models respectively explained 42 and 44% of the variation in the observed EQ-5D utility values and both had MADs of about 0.1. The confidence intervals of the mean difference between these predicted values and the observed values totally fell within the pre-defined equivalence margin of 0.03 points. These predicted values were also similar to the observed EQ-5D utility values in terms of their association with clinical variables.

Conclusion

At the group level, but not at the individual level, the mapping functions can accurately map the PDQ-8 outcomes to the EQ-5D utility index.

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Titel: Mapping the eight-item Parkinson’s Disease Questionnaire (PDQ-8) to the EQ-5D utility index
verfasst von: Y. B. Cheung
L. C. S. Tan
P. N. Lau
W. L. Au
N. Luo
Publikationsdatum: 01.11.2008
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 9/2008
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-008-9392-8

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Mapping the eight-item Parkinson’s Disease Questionnaire (PDQ-8) to the EQ-5D utility index

Abstract

Objective

Methods

Results

Conclusion

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Objective

Methods

Results

Conclusion

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