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Erschienen in: World Journal of Surgery 11/2018

21.05.2018 | Original Scientific Report

Massive Transfusion: The Revised Assessment of Bleeding and Transfusion (RABT) Score

verfasst von: Bellal Joseph, Muhammad Khan, Michael Truitt, Faisal Jehan, Narong Kulvatunyou, Asad Azim, Arpana Jain, Muhammad Zeeshan, Andrew Tang, Terence O’Keeffe

Erschienen in: World Journal of Surgery | Ausgabe 11/2018

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Abstract

Background

Massive transfusion (MT) is a lifesaving treatment for trauma patients with hemorrhagic shock, assessed by Assessment of Blood Consumption (ABC) Score based on mechanism of injury, systolic blood pressure (SBP), tachycardia, and FAST exam. The aim of this study was to assess the performance of ABC score by replacing hypotension and tachycardia; with Shock Index (SI) > 1.0 and including pelvic fractures.

Methods

We performed a 2-year (2014–2015) analysis of all high-level trauma activations and excluded patients dead on arrival. The ABC score was calculated using the 4-point score [blunt (0)/penetrating trauma (1), HR ≥ 120 (1), SBP ≤ 90 mmHg (1), and FAST positive (1)]. The Revised Assessment of Bleeding and Transfusion (RABT) score also included 4 points, calculated by replacing HR and SBP with SI > 1.0 and including pelvic fracture. AUROC compared performances of the two scores.

Results

A total of 380 patients were included. The overall MT was 27%. Patients receiving MT had higher median ABC scores [1.1 (0–2) vs. 1 (0–2), p = 0.15] and RABT scores [2 (1–3) vs. 1 (0–2), p < 0.001]. The RABT score had better discriminative power (AUROC = 0.828) compared to ABC score (AUROC = 0.617) for predicting the need for MT. Cutoff of RABT score ≥ 2 had a sensitivity of 84% and specificity of 77% for predicting need for MT compared to ABC score with 39% sensitivity and 72% specificity.

Conclusion

Replacement of hypotension and tachycardia with a SI > 1.0 and inclusion of pelvic fracture enhanced discrimination of ABC score for predicting the need for MT. The current ABC score would benefit from revision to more appropriately identify patients requiring MT.
Literatur
1.
Zurück zum Zitat Rhee P, Joseph B, Pandit V et al (2014) Increasing trauma deaths in the United States. Ann Surg 260:13–21CrossRef Rhee P, Joseph B, Pandit V et al (2014) Increasing trauma deaths in the United States. Ann Surg 260:13–21CrossRef
2.
Zurück zum Zitat Sobrino J, Shafi S (2013) Timing and causes of death after injuries. Proc Bayl Univ Med Center 26:120CrossRef Sobrino J, Shafi S (2013) Timing and causes of death after injuries. Proc Bayl Univ Med Center 26:120CrossRef
3.
Zurück zum Zitat Acosta JA, Yang JC, Winchell RJ et al (1998) Lethal injuries and time to death in a level I trauma center. J Am Coll Surg 186:528–533CrossRef Acosta JA, Yang JC, Winchell RJ et al (1998) Lethal injuries and time to death in a level I trauma center. J Am Coll Surg 186:528–533CrossRef
4.
Zurück zum Zitat Tisherman SA, Schmicker RH, Brasel KJ et al (2015) Detailed description of all deaths in both the shock and traumatic brain injury hypertonic saline trials of the Resuscitation Outcomes Consortium. Ann Surg 261:586CrossRef Tisherman SA, Schmicker RH, Brasel KJ et al (2015) Detailed description of all deaths in both the shock and traumatic brain injury hypertonic saline trials of the Resuscitation Outcomes Consortium. Ann Surg 261:586CrossRef
5.
Zurück zum Zitat Ley EJ, Clond MA, Srour MK et al (2011) Emergency department crystalloid resuscitation of 1.5 L or more is associated with increased mortality in elderly and nonelderly trauma patients. J Trauma Acute Care Surg 70:398–400CrossRef Ley EJ, Clond MA, Srour MK et al (2011) Emergency department crystalloid resuscitation of 1.5 L or more is associated with increased mortality in elderly and nonelderly trauma patients. J Trauma Acute Care Surg 70:398–400CrossRef
6.
Zurück zum Zitat Holcomb JB, Jenkins D, Rhee P et al (2007) Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma Acute Care Surg 62:307–310CrossRef Holcomb JB, Jenkins D, Rhee P et al (2007) Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma Acute Care Surg 62:307–310CrossRef
7.
Zurück zum Zitat Holcomb JB, Tilley BC, Baraniuk S et al (2015) Transfusion of plasma, platelets, and red blood cells in a 1: 1: 1 vs a 1: 1: 2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA 313:471–482CrossRef Holcomb JB, Tilley BC, Baraniuk S et al (2015) Transfusion of plasma, platelets, and red blood cells in a 1: 1: 1 vs a 1: 1: 2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA 313:471–482CrossRef
8.
Zurück zum Zitat Gonzalez EA, Moore FA, Holcomb JB et al (2007) Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma Acute Care Surg 62:112–119CrossRef Gonzalez EA, Moore FA, Holcomb JB et al (2007) Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma Acute Care Surg 62:112–119CrossRef
9.
Zurück zum Zitat Como JJ, Dutton RP, Scalea TM et al (2004) Blood transfusion rates in the care of acute trauma. Transfusion 44:809–813CrossRef Como JJ, Dutton RP, Scalea TM et al (2004) Blood transfusion rates in the care of acute trauma. Transfusion 44:809–813CrossRef
10.
Zurück zum Zitat McLaughlin DF, Niles SE, Salinas J et al (2008) A predictive model for massive transfusion in combat casualty patients. J Trauma Acute Care Surg 64:S57–S63CrossRef McLaughlin DF, Niles SE, Salinas J et al (2008) A predictive model for massive transfusion in combat casualty patients. J Trauma Acute Care Surg 64:S57–S63CrossRef
11.
Zurück zum Zitat Nunez TC, Voskresensky IV, Dossett LA et al (2009) Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)? J Trauma Acute Care Surg 66:346–352CrossRef Nunez TC, Voskresensky IV, Dossett LA et al (2009) Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)? J Trauma Acute Care Surg 66:346–352CrossRef
12.
Zurück zum Zitat Dente CJ, Shaz BH, Nicholas JM et al (2010) Early predictors of massive transfusion in patients sustaining torso gunshot wounds in a civilian level I trauma center. J Trauma Acute Care Surg 68:298–304CrossRef Dente CJ, Shaz BH, Nicholas JM et al (2010) Early predictors of massive transfusion in patients sustaining torso gunshot wounds in a civilian level I trauma center. J Trauma Acute Care Surg 68:298–304CrossRef
13.
Zurück zum Zitat Callcut RA, Johannigman JA, Kadon KS et al (2011) All massive transfusion criteria are not created equal: defining the predictive value of individual transfusion triggers to better determine who benefits from blood. J Trauma Acute Care Surg 70:794–801CrossRef Callcut RA, Johannigman JA, Kadon KS et al (2011) All massive transfusion criteria are not created equal: defining the predictive value of individual transfusion triggers to better determine who benefits from blood. J Trauma Acute Care Surg 70:794–801CrossRef
14.
Zurück zum Zitat Cotton BA, Dossett LA, Haut ER et al (2010) Multicenter validation of a simplified score to predict massive transfusion in trauma. J Trauma Acute Care Surg 69:S33–S39CrossRef Cotton BA, Dossett LA, Haut ER et al (2010) Multicenter validation of a simplified score to predict massive transfusion in trauma. J Trauma Acute Care Surg 69:S33–S39CrossRef
15.
Zurück zum Zitat Yücel N, Lefering R, Maegele M et al (2006) Trauma Associated Severe Hemorrhage (TASH)-Score: probability of mass transfusion as surrogate for life threatening hemorrhage after multiple trauma. J Trauma Acute Care Surg 60:1228–1237CrossRef Yücel N, Lefering R, Maegele M et al (2006) Trauma Associated Severe Hemorrhage (TASH)-Score: probability of mass transfusion as surrogate for life threatening hemorrhage after multiple trauma. J Trauma Acute Care Surg 60:1228–1237CrossRef
16.
Zurück zum Zitat Rainer TH, Ho AM, Yeung JH et al (2011) Early risk stratification of patients with major trauma requiring massive blood transfusion. Resuscitation 82:724–729CrossRef Rainer TH, Ho AM, Yeung JH et al (2011) Early risk stratification of patients with major trauma requiring massive blood transfusion. Resuscitation 82:724–729CrossRef
17.
Zurück zum Zitat Vandromme MJ, Griffin RL, McGwin G et al (2011) Prospective identification of patients at risk for massive transfusion: an imprecise endeavor. Am Surg 77:155–161PubMed Vandromme MJ, Griffin RL, McGwin G et al (2011) Prospective identification of patients at risk for massive transfusion: an imprecise endeavor. Am Surg 77:155–161PubMed
18.
Zurück zum Zitat Ruchholtz S, Pehle B, Lewan U et al (2006) The emergency room transfusion score (ETS): prediction of blood transfusion requirement in initial resuscitation after severe trauma. Transfus Med 16:49–56CrossRef Ruchholtz S, Pehle B, Lewan U et al (2006) The emergency room transfusion score (ETS): prediction of blood transfusion requirement in initial resuscitation after severe trauma. Transfus Med 16:49–56CrossRef
19.
Zurück zum Zitat Larson CR, White CE, Spinella PC et al (2010) Association of shock, coagulopathy, and initial vital signs with massive transfusion in combat casualties. J Trauma Acute Care Surg 69:S26–S32CrossRef Larson CR, White CE, Spinella PC et al (2010) Association of shock, coagulopathy, and initial vital signs with massive transfusion in combat casualties. J Trauma Acute Care Surg 69:S26–S32CrossRef
20.
Zurück zum Zitat Hoyt DB, Bulger EM, Knudson MM et al (1994) Death in the operating room: an analysis of a multi-center experience. J Trauma Acute Care Surg 37:426–432CrossRef Hoyt DB, Bulger EM, Knudson MM et al (1994) Death in the operating room: an analysis of a multi-center experience. J Trauma Acute Care Surg 37:426–432CrossRef
21.
Zurück zum Zitat Sauaia A, Moore FA, Moore EE et al (1995) Epidemiology of trauma deaths: a reassessment. J Trauma Acute Care Surg 38:185–193CrossRef Sauaia A, Moore FA, Moore EE et al (1995) Epidemiology of trauma deaths: a reassessment. J Trauma Acute Care Surg 38:185–193CrossRef
22.
Zurück zum Zitat Hess JR, Zimrin AB (2005) Massive blood transfusion for trauma. Curr Opin Hematol 12:488–492CrossRef Hess JR, Zimrin AB (2005) Massive blood transfusion for trauma. Curr Opin Hematol 12:488–492CrossRef
23.
Zurück zum Zitat Pandit V, Rhee P, Hashmi A et al (2014) Massive blood transfusion for trauma. J Trauma Acute Care Surg 76:1111–1115CrossRef Pandit V, Rhee P, Hashmi A et al (2014) Massive blood transfusion for trauma. J Trauma Acute Care Surg 76:1111–1115CrossRef
24.
Zurück zum Zitat Haider AA, Azim A, Rhee P et al (2016) Substituting systolic blood pressure with Shock Index in the National Trauma Triage Protocol. J Trauma Acute Care Surg 81:1136–1141CrossRef Haider AA, Azim A, Rhee P et al (2016) Substituting systolic blood pressure with Shock Index in the National Trauma Triage Protocol. J Trauma Acute Care Surg 81:1136–1141CrossRef
25.
Zurück zum Zitat Moreno C, Moore EE, Rosenberger A et al (1986) Hemorrhage associated with major pelvic fracture: a multispecialty challenge. J Trauma Acute Care Surg 26:987–994CrossRef Moreno C, Moore EE, Rosenberger A et al (1986) Hemorrhage associated with major pelvic fracture: a multispecialty challenge. J Trauma Acute Care Surg 26:987–994CrossRef
26.
Zurück zum Zitat Evers BM, Cryer HM, Miller FB (1989) Pelvic fracture hemorrhage: priorities in management. Arch Surg 124:422–424CrossRef Evers BM, Cryer HM, Miller FB (1989) Pelvic fracture hemorrhage: priorities in management. Arch Surg 124:422–424CrossRef
27.
Zurück zum Zitat Rothenberger D, Fischer R, Strate R et al (1978) The mortality associated with pelvic fractures. Surgery 84:356–361PubMed Rothenberger D, Fischer R, Strate R et al (1978) The mortality associated with pelvic fractures. Surgery 84:356–361PubMed
28.
Zurück zum Zitat Mutschler M, Nienaber U, Münzberg M et al (2013) The Shock Index revisited: a fast guide to transfusion requirement? A retrospective analysis on 21,853 patients derived from the trauma register DGU®. Crit Care 17:R172CrossRef Mutschler M, Nienaber U, Münzberg M et al (2013) The Shock Index revisited: a fast guide to transfusion requirement? A retrospective analysis on 21,853 patients derived from the trauma register DGU®. Crit Care 17:R172CrossRef
29.
Zurück zum Zitat Brasel KJ, Guse C, Gentilello LM et al (2007) Heart rate: is it truly a vital sign? J Trauma Acute Care Surg 62:812–817CrossRef Brasel KJ, Guse C, Gentilello LM et al (2007) Heart rate: is it truly a vital sign? J Trauma Acute Care Surg 62:812–817CrossRef
30.
Zurück zum Zitat Mutschler M, Nienaber U, Brockamp T et al (2013) A critical reappraisal of the ATLS classification of hypovolaemic shock: does it really reflect clinical reality? Resuscitation 84:309–313CrossRef Mutschler M, Nienaber U, Brockamp T et al (2013) A critical reappraisal of the ATLS classification of hypovolaemic shock: does it really reflect clinical reality? Resuscitation 84:309–313CrossRef
31.
Zurück zum Zitat Vandromme MJ, Griffin RL, Kerby JD et al (2011) Identifying risk for massive transfusion in the relatively normotensive patient: utility of the prehospital Shock Index. J Trauma Acute Care Surg 70:384–390CrossRef Vandromme MJ, Griffin RL, Kerby JD et al (2011) Identifying risk for massive transfusion in the relatively normotensive patient: utility of the prehospital Shock Index. J Trauma Acute Care Surg 70:384–390CrossRef
32.
Zurück zum Zitat Rau C-S, Wu S-C, Kuo SC et al (2016) Prediction of massive transfusion in trauma patients with Shock Index, modified Shock Index, and age Shock Index. Int J Environ Res Public Health 13:683CrossRef Rau C-S, Wu S-C, Kuo SC et al (2016) Prediction of massive transfusion in trauma patients with Shock Index, modified Shock Index, and age Shock Index. Int J Environ Res Public Health 13:683CrossRef
33.
Zurück zum Zitat Schroll R, Swift D, Tatum D et al (2017) Accuracy of Shock Index versus ABC score to predict need for massive transfusion in trauma patients. Injury 49:15CrossRef Schroll R, Swift D, Tatum D et al (2017) Accuracy of Shock Index versus ABC score to predict need for massive transfusion in trauma patients. Injury 49:15CrossRef
Metadaten
Titel
Massive Transfusion: The Revised Assessment of Bleeding and Transfusion (RABT) Score
verfasst von
Bellal Joseph
Muhammad Khan
Michael Truitt
Faisal Jehan
Narong Kulvatunyou
Asad Azim
Arpana Jain
Muhammad Zeeshan
Andrew Tang
Terence O’Keeffe
Publikationsdatum
21.05.2018
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 11/2018
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-018-4674-y

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