Skip to main content
Erschienen in: Clinical Oral Investigations 2/2015

01.03.2015 | Original Article

Masticatory rehabilitation following upper and lower jaw reconstruction using vascularised free fibula flap and enossal implants—19 years of experience with a comprehensive concept

verfasst von: Samer George Hakim, Harald Kimmerle, Thomas Trenkle, Peter Sieg, Hans-Christian Jacobsen

Erschienen in: Clinical Oral Investigations | Ausgabe 2/2015

Einloggen, um Zugang zu erhalten

Abstract

Objectives

Conventional prosthesis is generally inapplicable following reconstruction with free fibula flaps (FFF) due to impaired bone and soft tissue conditions, and rehabilitation via enossal implants in FFF is relatively novel. This retrospective study aimed to document the surgical aspects of this option and to describe related supplementary procedures that can help optimise the definitive outcome.

Material and methods

One hundred nineteen implants were inserted within FFFs in 37 patients (mean age 51.8 ± 10.6 years), who underwent ablative surgery of the maxilla (3) and mandible (34). In a cross-sectional study design with a follow-up period of 3–172 months, we analysed types and configurations of graft design, patterns of implant insertion and methods for prosthetic rehabilitation as well as primary stability and survival rate.

Results

Most patients underwent jaw reconstruction using a mono-barrel FFF (14 osseous and 18 osteocutaneous/osteomyocutaneous); three patients received double-barrel reconstruction of the mandible. Three patients with maxillary defects were reconstructed using mono-barrel grafts (one osteocutaneous and two prefabricated grafts). Pre-prosthetic procedures were required in 23 patients to optimise conditions in the peri-implant soft tissue. Iliac bone onlay graft was used in six patients to achieve appropriate vertical height in mono-barrel grafts. A total of 10 implants in eight patients (five irradiated) could not be loaded. All other implants showed stable osseous integration and satisfactory peri-implant soft tissue conditions.

Conclusion

Masticatory rehabilitation can be achieved using enossal implants inserted in FFF. Special requirements can be met through selection of an appropriate graft configuration and optimal implant positioning. Supplementary pre-prosthetic procedures are usually required as they improve long-term survival.

Clinical relevance

This overview provides a reliable and comprehensive algorithm for standard implant-borne rehabilitation of patients with fibula grafts.
Literatur
1.
Zurück zum Zitat Sieg P, Zieron JO, Bierwolf S, Hakim SG (2002) Defect-related variations in mandibular reconstruction using fibula grafts. A review of 96 cases. Br J Oral Maxillofac Surg 40:322–329CrossRefPubMed Sieg P, Zieron JO, Bierwolf S, Hakim SG (2002) Defect-related variations in mandibular reconstruction using fibula grafts. A review of 96 cases. Br J Oral Maxillofac Surg 40:322–329CrossRefPubMed
2.
Zurück zum Zitat Sieg P, Taner C, Hakim SG, Jacobsen HC (2010) Long-term evaluation of donor site morbidity after free fibula transfer. Br J Oral Maxillofac Surg 48:267–270CrossRefPubMed Sieg P, Taner C, Hakim SG, Jacobsen HC (2010) Long-term evaluation of donor site morbidity after free fibula transfer. Br J Oral Maxillofac Surg 48:267–270CrossRefPubMed
3.
Zurück zum Zitat Hakim SG, Jeske G, Jacobsen HC, Sieg P (2012) The eligibility of the free fibula graft for masticatory rehabilitation using monocortical implants insertion—a morphologic and biomechanical study. Clin Oral Investig 16:673–678CrossRefPubMed Hakim SG, Jeske G, Jacobsen HC, Sieg P (2012) The eligibility of the free fibula graft for masticatory rehabilitation using monocortical implants insertion—a morphologic and biomechanical study. Clin Oral Investig 16:673–678CrossRefPubMed
4.
Zurück zum Zitat Kramer FJ, Dempf R, Bremer B (2005) Efficacy of dental implants placed into fibula-free flaps for orofacial reconstruction. Clin Oral Implants Res 16:80–88CrossRefPubMed Kramer FJ, Dempf R, Bremer B (2005) Efficacy of dental implants placed into fibula-free flaps for orofacial reconstruction. Clin Oral Implants Res 16:80–88CrossRefPubMed
5.
Zurück zum Zitat Chen ZW, Yan W (1983) The study and clinical application of the osteocutaneous flap of fibula. Microsurgery 4:11–16CrossRefPubMed Chen ZW, Yan W (1983) The study and clinical application of the osteocutaneous flap of fibula. Microsurgery 4:11–16CrossRefPubMed
6.
Zurück zum Zitat Gilbert A (1981) Free vascularized bone grafts. Int Surg 66:27–31PubMed Gilbert A (1981) Free vascularized bone grafts. Int Surg 66:27–31PubMed
7.
Zurück zum Zitat Hidalgo DA (1989) Fibula free flap: a new method of mandible reconstruction. Plast Reconstr Surg 84:71–79CrossRefPubMed Hidalgo DA (1989) Fibula free flap: a new method of mandible reconstruction. Plast Reconstr Surg 84:71–79CrossRefPubMed
8.
Zurück zum Zitat Rohner D, Jaquiery C, Kunz C, Bucher P, Maas H, Hammer B (2003) Maxillofacial reconstruction with prefabricated osseous free flaps: a 3-year experience with 24 patients. Plast Reconstr Surg 112:748–757CrossRefPubMed Rohner D, Jaquiery C, Kunz C, Bucher P, Maas H, Hammer B (2003) Maxillofacial reconstruction with prefabricated osseous free flaps: a 3-year experience with 24 patients. Plast Reconstr Surg 112:748–757CrossRefPubMed
9.
Zurück zum Zitat Jewer DD, Boyd JB, Manktelow RT, Zuker RM, Rosen IB, Gullane PJ, Rotstein LE, Freeman JE (1989) Orofacial and mandibular reconstruction with the iliac crest free flap: a review of 60 cases and a new method of classification. Plast Reconstr Surg 84:391–403, discussion 404-395CrossRefPubMed Jewer DD, Boyd JB, Manktelow RT, Zuker RM, Rosen IB, Gullane PJ, Rotstein LE, Freeman JE (1989) Orofacial and mandibular reconstruction with the iliac crest free flap: a review of 60 cases and a new method of classification. Plast Reconstr Surg 84:391–403, discussion 404-395CrossRefPubMed
10.
Zurück zum Zitat Brown JS, Shaw RJ (2010) Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol 11:1001–1008CrossRefPubMed Brown JS, Shaw RJ (2010) Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol 11:1001–1008CrossRefPubMed
11.
Zurück zum Zitat Hakim SG, Driemel O, Jacobsen HC, Hermes D, Sieg P (2006) Exposure of implants using a modified multiple-flap transposition vestibuloplasty. Br J Oral Maxillofac Surg 44:507–510CrossRefPubMed Hakim SG, Driemel O, Jacobsen HC, Hermes D, Sieg P (2006) Exposure of implants using a modified multiple-flap transposition vestibuloplasty. Br J Oral Maxillofac Surg 44:507–510CrossRefPubMed
12.
Zurück zum Zitat Cheung LK, Leung AC (2003) Dental implants in reconstructed jaws: implant longevity and peri-implant tissue outcomes. J Oral Maxillofac Surg 61:1263–1274CrossRefPubMed Cheung LK, Leung AC (2003) Dental implants in reconstructed jaws: implant longevity and peri-implant tissue outcomes. J Oral Maxillofac Surg 61:1263–1274CrossRefPubMed
13.
Zurück zum Zitat Raoul G, Ruhin B, Briki S, Lauwers L, Haurou Patou G, Capet JP, Maes JM, Ferri J (2009) Microsurgical reconstruction of the jaw with fibular grafts and implants. J Craniofac Surg 20:2105–2117CrossRefPubMed Raoul G, Ruhin B, Briki S, Lauwers L, Haurou Patou G, Capet JP, Maes JM, Ferri J (2009) Microsurgical reconstruction of the jaw with fibular grafts and implants. J Craniofac Surg 20:2105–2117CrossRefPubMed
14.
Zurück zum Zitat Shen Y, Guo XH, Sun J, Li J, Shi J, Huang W, Ow A (2013) Double-barrel vascularised fibula graft in mandibular reconstruction: a 10-year experience with an algorithm. J Plast Reconstr Aesthet Surg 66:364–371CrossRefPubMed Shen Y, Guo XH, Sun J, Li J, Shi J, Huang W, Ow A (2013) Double-barrel vascularised fibula graft in mandibular reconstruction: a 10-year experience with an algorithm. J Plast Reconstr Aesthet Surg 66:364–371CrossRefPubMed
15.
Zurück zum Zitat Levin L, Carrasco L, Kazemi A, Chalian A (2003) Enhancement of the fibula free flap by alveolar distraction for dental implant restoration: report of a case. Facial Plast Surg 19:87–94CrossRefPubMed Levin L, Carrasco L, Kazemi A, Chalian A (2003) Enhancement of the fibula free flap by alveolar distraction for dental implant restoration: report of a case. Facial Plast Surg 19:87–94CrossRefPubMed
16.
Zurück zum Zitat Nocini PF, Wangerin K, Albanese M, Kretschmer W, Cortelazzi R (2000) Vertical distraction of a free vascularized fibula flap in a reconstructed hemimandible: case report. J Craniomaxillofac Surg 28:20–24CrossRefPubMed Nocini PF, Wangerin K, Albanese M, Kretschmer W, Cortelazzi R (2000) Vertical distraction of a free vascularized fibula flap in a reconstructed hemimandible: case report. J Craniomaxillofac Surg 28:20–24CrossRefPubMed
17.
Zurück zum Zitat Hayter JP, Cawood JI (1996) Oral rehabilitation with endosteal implants and free flaps. Int J Oral Maxillofac Surg 25:3–12CrossRefPubMed Hayter JP, Cawood JI (1996) Oral rehabilitation with endosteal implants and free flaps. Int J Oral Maxillofac Surg 25:3–12CrossRefPubMed
18.
Zurück zum Zitat Lee JH, Kim MJ, Choi WS, Yoon PY, Ahn KM, Myung H, Hwang SJ, Seo BM, Choi JY, Choung PH, Kim SM (2004) Concomitant reconstruction of mandibular basal and alveolar bone with a free fibular flap. Int J Oral Maxillofac Surg 33:150–156CrossRefPubMed Lee JH, Kim MJ, Choi WS, Yoon PY, Ahn KM, Myung H, Hwang SJ, Seo BM, Choi JY, Choung PH, Kim SM (2004) Concomitant reconstruction of mandibular basal and alveolar bone with a free fibular flap. Int J Oral Maxillofac Surg 33:150–156CrossRefPubMed
19.
Zurück zum Zitat Trulsson M (2006) Sensory-motor function of human periodontal mechanoreceptors. J Oral Rehabil 33:262–273CrossRefPubMed Trulsson M (2006) Sensory-motor function of human periodontal mechanoreceptors. J Oral Rehabil 33:262–273CrossRefPubMed
20.
Zurück zum Zitat Lioubavina-Hack N, Lang NP, Karring T (2006) Significance of primary stability for osseointegration of dental implants. Clin Oral Implants Res 17:244–250CrossRefPubMed Lioubavina-Hack N, Lang NP, Karring T (2006) Significance of primary stability for osseointegration of dental implants. Clin Oral Implants Res 17:244–250CrossRefPubMed
21.
Zurück zum Zitat Lachmann S, Jager B, Axmann D, Gomez-Roman G, Groten M, Weber H (2006) Resonance frequency analysis and damping capacity assessment. Part I: an in vitro study on measurement reliability and a method of comparison in the determination of primary dental implant stability. Clin Oral Implants Res 17:75–79CrossRefPubMed Lachmann S, Jager B, Axmann D, Gomez-Roman G, Groten M, Weber H (2006) Resonance frequency analysis and damping capacity assessment. Part I: an in vitro study on measurement reliability and a method of comparison in the determination of primary dental implant stability. Clin Oral Implants Res 17:75–79CrossRefPubMed
22.
Zurück zum Zitat Winkler S, Morris HF, Spray JR (2001) Stability of implants and natural teeth as determined by the Periotest over 60 months of function. J Oral Implantol 27:198–203CrossRefPubMed Winkler S, Morris HF, Spray JR (2001) Stability of implants and natural teeth as determined by the Periotest over 60 months of function. J Oral Implantol 27:198–203CrossRefPubMed
23.
Zurück zum Zitat Chang YM, Wallace CG, Tsai CY, Shen YF, Hsu YM, Wei FC (2011) Dental implant outcome after primary implantation into double-barreled fibula osteoseptocutaneous free flap-reconstructed mandible. Plast Reconstr Surg 128:1220–1228CrossRefPubMed Chang YM, Wallace CG, Tsai CY, Shen YF, Hsu YM, Wei FC (2011) Dental implant outcome after primary implantation into double-barreled fibula osteoseptocutaneous free flap-reconstructed mandible. Plast Reconstr Surg 128:1220–1228CrossRefPubMed
24.
Zurück zum Zitat Roumanas ED, Markowitz BL, Lorant JA, Calcaterra TC, Jones NF, Beumer J 3rd (1997) Reconstructed mandibular defects: fibula free flaps and osseointegrated implants. Plast Reconstr Surg 99:356–365CrossRefPubMed Roumanas ED, Markowitz BL, Lorant JA, Calcaterra TC, Jones NF, Beumer J 3rd (1997) Reconstructed mandibular defects: fibula free flaps and osseointegrated implants. Plast Reconstr Surg 99:356–365CrossRefPubMed
25.
Zurück zum Zitat Rohner D, Bucher P, Kunz C, Hammer B, Schenk RK, Prein J (2002) Treatment of severe atrophy of the maxilla with the prefabricated free vascularized fibula flap. Clin Oral Implants Res 13:44–52CrossRefPubMed Rohner D, Bucher P, Kunz C, Hammer B, Schenk RK, Prein J (2002) Treatment of severe atrophy of the maxilla with the prefabricated free vascularized fibula flap. Clin Oral Implants Res 13:44–52CrossRefPubMed
26.
Zurück zum Zitat Gbara A, Darwich K, Li L, Schmelzle R, Blake F (2007) Long-term results of jaw reconstruction with microsurgical fibula grafts and dental implants. J Oral Maxillofac Surg 65:1005–1009CrossRefPubMed Gbara A, Darwich K, Li L, Schmelzle R, Blake F (2007) Long-term results of jaw reconstruction with microsurgical fibula grafts and dental implants. J Oral Maxillofac Surg 65:1005–1009CrossRefPubMed
27.
Zurück zum Zitat Garrett N, Roumanas ED, Blackwell KE, Freymiller E, Abemayor E, Wong WK, Gerratt B, Berke G, Beumer J 3rd, Kapur KK (2006) Efficacy of conventional and implant-supported mandibular resection prostheses: study overview and treatment outcomes. J Prosthet Dent 96:13–24CrossRefPubMed Garrett N, Roumanas ED, Blackwell KE, Freymiller E, Abemayor E, Wong WK, Gerratt B, Berke G, Beumer J 3rd, Kapur KK (2006) Efficacy of conventional and implant-supported mandibular resection prostheses: study overview and treatment outcomes. J Prosthet Dent 96:13–24CrossRefPubMed
28.
Zurück zum Zitat Chiapasco M, Biglioli F, Autelitano L, Romeo E, Brusati R (2006) Clinical outcome of dental implants placed in fibula-free flaps used for the reconstruction of maxillo-mandibular defects following ablation for tumors or osteoradionecrosis. Clin Oral Implants Res 17:220–228CrossRefPubMed Chiapasco M, Biglioli F, Autelitano L, Romeo E, Brusati R (2006) Clinical outcome of dental implants placed in fibula-free flaps used for the reconstruction of maxillo-mandibular defects following ablation for tumors or osteoradionecrosis. Clin Oral Implants Res 17:220–228CrossRefPubMed
29.
Zurück zum Zitat Chiapasco M, Romeo E, Coggiola A, Brusati R (2011) Long-term outcome of dental implants placed in revascularized fibula free flaps used for the reconstruction of maxillo-mandibular defects due to extreme atrophy. Clin Oral Implants Res 22:83–91CrossRefPubMed Chiapasco M, Romeo E, Coggiola A, Brusati R (2011) Long-term outcome of dental implants placed in revascularized fibula free flaps used for the reconstruction of maxillo-mandibular defects due to extreme atrophy. Clin Oral Implants Res 22:83–91CrossRefPubMed
30.
Zurück zum Zitat Okay DJ, Buchbinder D, Urken M, Jacobson A, Lazarus C, Persky M (2013) Computer-assisted implant rehabilitation of maxillomandibular defects reconstructed with vascularized bone free flaps. JAMA Otolaryngol Head Neck Surg 139:371–381CrossRefPubMed Okay DJ, Buchbinder D, Urken M, Jacobson A, Lazarus C, Persky M (2013) Computer-assisted implant rehabilitation of maxillomandibular defects reconstructed with vascularized bone free flaps. JAMA Otolaryngol Head Neck Surg 139:371–381CrossRefPubMed
31.
Zurück zum Zitat Zheng GS, Su YX, Liao GQ, Chen ZF, Wang L, Jiao PF, Liu HC, Zhong YQ, Zhang TH, Liang YJ (2012) Mandible reconstruction assisted by preoperative virtual surgical simulation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 113:604–611CrossRef Zheng GS, Su YX, Liao GQ, Chen ZF, Wang L, Jiao PF, Liu HC, Zhong YQ, Zhang TH, Liang YJ (2012) Mandible reconstruction assisted by preoperative virtual surgical simulation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 113:604–611CrossRef
32.
Zurück zum Zitat Ciocca L, Mazzoni S, Fantini M, Persiani F, Marchetti C, Scotti R (2012) CAD/CAM guided secondary mandibular reconstruction of a discontinuity defect after ablative cancer surgery. J Craniomaxillofac Surg 40:e511–e515CrossRefPubMed Ciocca L, Mazzoni S, Fantini M, Persiani F, Marchetti C, Scotti R (2012) CAD/CAM guided secondary mandibular reconstruction of a discontinuity defect after ablative cancer surgery. J Craniomaxillofac Surg 40:e511–e515CrossRefPubMed
33.
Zurück zum Zitat Valentini V, Agrillo A, Battisti A, Gennaro P, Calabrese L, Iannetti G (2005) Surgical planning in reconstruction of mandibular defect with fibula free flap: 15 patients. J Craniofac Surg 16:601–607CrossRefPubMed Valentini V, Agrillo A, Battisti A, Gennaro P, Calabrese L, Iannetti G (2005) Surgical planning in reconstruction of mandibular defect with fibula free flap: 15 patients. J Craniofac Surg 16:601–607CrossRefPubMed
34.
Zurück zum Zitat Eckardt A, Swennen GR (2005) Virtual planning of composite mandibular reconstruction with free fibula bone graft. J Craniofac Surg 16:1137–1140CrossRefPubMed Eckardt A, Swennen GR (2005) Virtual planning of composite mandibular reconstruction with free fibula bone graft. J Craniofac Surg 16:1137–1140CrossRefPubMed
35.
Zurück zum Zitat Schliephake H, Schmelzeisen R, Husstedt H, Schmidt-Wondera LU (1999) Comparison of the late results of mandibular reconstruction using nonvascularized or vascularized grafts and dental implants. J Oral Maxillofac Surg 57:944–950, discussion 950-941CrossRefPubMed Schliephake H, Schmelzeisen R, Husstedt H, Schmidt-Wondera LU (1999) Comparison of the late results of mandibular reconstruction using nonvascularized or vascularized grafts and dental implants. J Oral Maxillofac Surg 57:944–950, discussion 950-941CrossRefPubMed
Metadaten
Titel
Masticatory rehabilitation following upper and lower jaw reconstruction using vascularised free fibula flap and enossal implants—19 years of experience with a comprehensive concept
verfasst von
Samer George Hakim
Harald Kimmerle
Thomas Trenkle
Peter Sieg
Hans-Christian Jacobsen
Publikationsdatum
01.03.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 2/2015
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-014-1247-9

Weitere Artikel der Ausgabe 2/2015

Clinical Oral Investigations 2/2015 Zur Ausgabe

Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Zahnmedizin und bleiben Sie gut informiert – ganz bequem per eMail.