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Erschienen in: Sleep and Breathing 4/2020

07.02.2020 | Sleep Breathing Physiology and Disorders • Original Article

Measurement of upper airway resistances: A simple way to assess its collapsibility?

verfasst von: Gemma Rubinos Cuadrado, Ramón Fernández Álvarez, Julia Herrero Huertas, Maria Jose Vazquez Lopez, Marta Iscar Urrutia, Pere Casan Clara

Erschienen in: Sleep and Breathing | Ausgabe 4/2020

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Abstract

Purpose

The collapsibility of the upper airway is a key factor in the pathogenesis of obstructive sleep apnea (OSA). The exact measurement of this parameter, typically performed by obtaining the critical pressure (Pcrit), has not been introduced into clinical practice. The techniques that are used to measure the upper airway resistance could provide information on its the collapsibility of the airway. The aim of this study was to associate resistance in the upper airway with the presence of OSA.

Methods

Using a cross-sectional design with a control group, consecutive cases that were seen in the Chest Diseases Sleep Unit were recruited after undergoing nocturnal polysomnography. The upper airway collapsibility was determined based on the change in its resistance from the standing position to the supine position with a flow interruption (Rint) device by measuring the angle formed between the pressure/flow lines (PF angle) between the two positions.

Results

The PF angle was greater in the OSA group than in the controls: 7.5° (4) vs. 4° (2) (P < .001), with a positive correlation between the width of the angle and the apnea-hypopnea index (AHI) (r: 0.28, P = .03). Placing the threshold level at 10°, a sensitivity of 25% was obtained, along with a specificity of 96%, for the diagnosis of OSA.

Conclusion

The measurement of resistance in the upper airway using flow interruption (Rint) can predict the presence of moderate and severe OSA with high specificity but low sensitivity.
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Metadaten
Titel
Measurement of upper airway resistances: A simple way to assess its collapsibility?
verfasst von
Gemma Rubinos Cuadrado
Ramón Fernández Álvarez
Julia Herrero Huertas
Maria Jose Vazquez Lopez
Marta Iscar Urrutia
Pere Casan Clara
Publikationsdatum
07.02.2020
Verlag
Springer International Publishing
Erschienen in
Sleep and Breathing / Ausgabe 4/2020
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-020-02026-z

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