Skip to main content
Erschienen in: International Ophthalmology 1/2017

24.05.2016 | Original Paper

Measurements of central corneal thickness and endothelial parameters with three different non-contact specular microscopy devices

verfasst von: Ozgur Cakici, Remzi Karadag, Huseyin Bayramlar, Efe Koyun

Erschienen in: International Ophthalmology | Ausgabe 1/2017

Einloggen, um Zugang zu erhalten

Abstract

We aimed to compare the measurements of central corneal thickness (CCT) and endothelial parameters with three different non-contact specular microscopy (SM) devices. Fifteen eyes of 15 healthy individuals (6 males; 9 females) were enrolled in the study. Mean age was 37.93 ± 15.13 years. Endothelial parameters and CCT were measured with Nidek CEM-530, Topcon SP-3000P, and Tomey EM-3000 SM devices by the same physician. Endothelial parameters included endothelial cell count (ECC), maximum, minimum, and average endothelial cell size. and hexagonality ratio. There were no statistically significant differences in ECC, CTT, and average endothelial size (AES) between the devices (p > 0.05). The measurement of maximum endothelial size (MES) was different between Nidek SM and Topcon SM devices (p = 0.001), but there was no difference in MES between Nidek SM and Tomey SM (p = 0.058), and between Topcon SM and Tomey SM (p = 0.081). There was no difference in minimum endothelial size (MinES) between Nidek SM and Topcon SM (p = 0.794); however, there was a significant difference in MinES between Tomey SM and Nidek SM (p < 0.001), and between Tomey SM and Topcon SM (p < 0.001). Comparison of hexagonality ratio showed statistically significant difference between the devices (p < 0.001). No significant differences in the measurements of ECC, CCT, and AES were detected between different SM devices, whereas a statistically significant difference in hexagonality ratio was detected between the devices. These devices should not be used alternatively in the endothelial morphology assessment in patient’s follow-up.
Literatur
1.
Zurück zum Zitat Martin R, de Juan V, Rodriguez G et al (2008) Contact lens-induced corneal peripheral swelling differences with extended wears. Cornea 27:976–979CrossRefPubMed Martin R, de Juan V, Rodriguez G et al (2008) Contact lens-induced corneal peripheral swelling differences with extended wears. Cornea 27:976–979CrossRefPubMed
2.
Zurück zum Zitat Gordon MO, Beiser JA, Brandt JD et al (2002) The ocular hypertension treatment study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol 20:714–720CrossRef Gordon MO, Beiser JA, Brandt JD et al (2002) The ocular hypertension treatment study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol 20:714–720CrossRef
3.
Zurück zum Zitat Herndon LW, Weizer JS, Stinnett SS (2004) Central corneal thickness as a risk factor for advanced glaucoma damage. Arch Ophthalmol 122:17–21CrossRefPubMed Herndon LW, Weizer JS, Stinnett SS (2004) Central corneal thickness as a risk factor for advanced glaucoma damage. Arch Ophthalmol 122:17–21CrossRefPubMed
4.
Zurück zum Zitat Ou RJ, Shaw EL, Glasgow BJ (2002) Keratectasia after laser in situ keratomileusis (LASIK): evaluation of the calculated residual stromal bed thickness. Am J Ophthalmol 134:771–773CrossRefPubMed Ou RJ, Shaw EL, Glasgow BJ (2002) Keratectasia after laser in situ keratomileusis (LASIK): evaluation of the calculated residual stromal bed thickness. Am J Ophthalmol 134:771–773CrossRefPubMed
5.
Zurück zum Zitat Nucci P, Brancato R, Mets MB et al (1990) Normal endothelial cell density range in childhood. Arch Ophthalmol 108:247–248CrossRefPubMed Nucci P, Brancato R, Mets MB et al (1990) Normal endothelial cell density range in childhood. Arch Ophthalmol 108:247–248CrossRefPubMed
6.
Zurück zum Zitat Bourne W, Nelson L, Hodge D (1997) Central corneal endothelial cell changes over a ten-year period. Invest Ophthalmol Vis Sci 38:779–782PubMed Bourne W, Nelson L, Hodge D (1997) Central corneal endothelial cell changes over a ten-year period. Invest Ophthalmol Vis Sci 38:779–782PubMed
7.
Zurück zum Zitat Matsuda M, Yee R, Edelhauser H (1985) Comparison of the corneal endothelium in an American and Japanese population. Arch Ophthalmol 103:68–70CrossRefPubMed Matsuda M, Yee R, Edelhauser H (1985) Comparison of the corneal endothelium in an American and Japanese population. Arch Ophthalmol 103:68–70CrossRefPubMed
8.
Zurück zum Zitat Rao S, Fogla R, Gangadharan S et al (2000) Corneal endothelial cell density and morphology in normal Indian eyes. Cornea 19:820–823CrossRefPubMed Rao S, Fogla R, Gangadharan S et al (2000) Corneal endothelial cell density and morphology in normal Indian eyes. Cornea 19:820–823CrossRefPubMed
9.
Zurück zum Zitat Guell JL, El Husseiny MA, Manero F et al (2014) Historical review and update of surgical treatment for corneal endothelial diseases. Ophthalmol Ther 18:18 Guell JL, El Husseiny MA, Manero F et al (2014) Historical review and update of surgical treatment for corneal endothelial diseases. Ophthalmol Ther 18:18
10.
Zurück zum Zitat Ho JW, Afshari NA (2015) Advances in cataract surgery: preserving the corneal endothelium. Curr Opin Ophthalmol 26:22–27CrossRefPubMed Ho JW, Afshari NA (2015) Advances in cataract surgery: preserving the corneal endothelium. Curr Opin Ophthalmol 26:22–27CrossRefPubMed
11.
Zurück zum Zitat Salvetat ML, Zeppieri M, Miani F et al (2011) Comparison between laser scanning in vivo confocal microscopy and noncontact specular microscopy in assessing corneal endothelial cell density and central corneal thickness. Cornea 30:754–759CrossRefPubMed Salvetat ML, Zeppieri M, Miani F et al (2011) Comparison between laser scanning in vivo confocal microscopy and noncontact specular microscopy in assessing corneal endothelial cell density and central corneal thickness. Cornea 30:754–759CrossRefPubMed
12.
Zurück zum Zitat Laing RA, Oak SS, Leibowitz HM (1998) Specialized microscopy of the cornea. In: Leibowitz HM, Warring GO III (eds) Corneal disorders—clinical diagnosis and management. WB Saunders, Philadelphia, pp 83–122 Laing RA, Oak SS, Leibowitz HM (1998) Specialized microscopy of the cornea. In: Leibowitz HM, Warring GO III (eds) Corneal disorders—clinical diagnosis and management. WB Saunders, Philadelphia, pp 83–122
13.
Zurück zum Zitat Mencucci R, Ponchietti C, Virgili G et al (2006) Corneal endothelial damage after cataract surgery: microincision versus standard technique. J Cataract Refract Surg 32:1351–1354CrossRefPubMed Mencucci R, Ponchietti C, Virgili G et al (2006) Corneal endothelial damage after cataract surgery: microincision versus standard technique. J Cataract Refract Surg 32:1351–1354CrossRefPubMed
14.
Zurück zum Zitat Plainer S, Wenzl E, Saalabian AA et al (2011) Long-term follow-up with I-CARE phakic IOLs. Br J Ophthalmol 95:710–714CrossRefPubMed Plainer S, Wenzl E, Saalabian AA et al (2011) Long-term follow-up with I-CARE phakic IOLs. Br J Ophthalmol 95:710–714CrossRefPubMed
15.
Zurück zum Zitat Bao F, Wang Q, Cheng S et al (2014) Comparison and evaluation of central corneal thickness using 2 new noncontact specular microscopes and conventional pachymetry devices. Cornea 33:576–581CrossRefPubMed Bao F, Wang Q, Cheng S et al (2014) Comparison and evaluation of central corneal thickness using 2 new noncontact specular microscopes and conventional pachymetry devices. Cornea 33:576–581CrossRefPubMed
16.
Zurück zum Zitat de Sanctis U, Machetta F, Razzano L et al (2006) Corneal endothelium evaluation with 2 noncontact specular microscopes and their semiautomated methods of analysis. Cornea 25:501–506CrossRefPubMed de Sanctis U, Machetta F, Razzano L et al (2006) Corneal endothelium evaluation with 2 noncontact specular microscopes and their semiautomated methods of analysis. Cornea 25:501–506CrossRefPubMed
17.
Zurück zum Zitat Szalai E, Nemeth G, Berta A et al (2011) Evaluation of the corneal endothelium using noncontact and contact specular microscopy. Cornea 30:567–570CrossRefPubMed Szalai E, Nemeth G, Berta A et al (2011) Evaluation of the corneal endothelium using noncontact and contact specular microscopy. Cornea 30:567–570CrossRefPubMed
18.
Zurück zum Zitat Al-Ageel S, Al-Muammar AM (2009) Comparison of central corneal thickness measurements by Pentacam, noncontact specular microscope, and ultrasound pachymetry in normal and post-LASIK eyes. Saudi J Ophthalmol 23:181–187CrossRefPubMedPubMedCentral Al-Ageel S, Al-Muammar AM (2009) Comparison of central corneal thickness measurements by Pentacam, noncontact specular microscope, and ultrasound pachymetry in normal and post-LASIK eyes. Saudi J Ophthalmol 23:181–187CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Almubrad TM, Osuagwu UL, Alabbadi I et al (2011) Comparison of the precision of the Topcon SP-3000P specular microscope and an ultrasound pachymeter. Clin Ophthalmol 5:871–876CrossRefPubMedPubMedCentral Almubrad TM, Osuagwu UL, Alabbadi I et al (2011) Comparison of the precision of the Topcon SP-3000P specular microscope and an ultrasound pachymeter. Clin Ophthalmol 5:871–876CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat González-Pérez J, González-Méijome JM, Rodríguez Ares MT et al (2011) Central corneal thickness measured with three optical devices and ultrasound pachymetry. Eye Contact Lens 37:66–70CrossRefPubMed González-Pérez J, González-Méijome JM, Rodríguez Ares MT et al (2011) Central corneal thickness measured with three optical devices and ultrasound pachymetry. Eye Contact Lens 37:66–70CrossRefPubMed
21.
Zurück zum Zitat Tai LY, Khaw KW, Ng CM et al (2013) Central corneal thickness measurements with different imaging devices and ultrasound pachymetry. Cornea 32:766–771CrossRefPubMed Tai LY, Khaw KW, Ng CM et al (2013) Central corneal thickness measurements with different imaging devices and ultrasound pachymetry. Cornea 32:766–771CrossRefPubMed
Metadaten
Titel
Measurements of central corneal thickness and endothelial parameters with three different non-contact specular microscopy devices
verfasst von
Ozgur Cakici
Remzi Karadag
Huseyin Bayramlar
Efe Koyun
Publikationsdatum
24.05.2016
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 1/2017
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-016-0264-x

Weitere Artikel der Ausgabe 1/2017

International Ophthalmology 1/2017 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Open Access 22.02.2024 | Peeling | Originalien

Selektive Vitalfarbstoffe in der Makulachirurgie

Erhöhen sie die Wahrscheinlichkeit der intraoperativen ILM-Identifizierung auch bei einem erfahrenen Operateur?

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.