Mechanistic Insights into Calcium Oxalate Crystals in Aspergillosis of the Maxillary Sinus
- 01.12.2026
- Image
Erschienen in:
- Verfasst von
- Akshay Trimukhe
- Krushna Bhatt
- Asit Ranjan Mridha
- Varun Surya
- Deepika Mishra
- Rasla P C
- Erschienen in
- Head and Neck Pathology | Ausgabe 1/2026
Abstract
Background
Aspergillus species can induce calcium oxalate crystal deposition, serving as an important diagnostic marker when typical fruiting bodies or ancillary techniques are unavailable.
Case presentation
We report a 35-year-old male with recurrent oroantral fistula and maxillary sinus opacity. Histopathology demonstrated septate hyphae and birefringent calcium oxalate crystals under polarized light, confirming non-invasive aspergillosis.Oxalosis, frequently linked to Aspergillus niger, contributes to mucosal destruction through vascular compromise and oxidative injury.
Conclusion
Recognition of these crystals is crucial for differentiating Aspergillus from other filamentous fungi and underscores their diagnostic, pathogenic, and prognostic significance in sinonasal disease when conventional molecular methods are not employed.
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- Titel
- Mechanistic Insights into Calcium Oxalate Crystals in Aspergillosis of the Maxillary Sinus
- Verfasst von
-
Akshay Trimukhe
Krushna Bhatt
Asit Ranjan Mridha
Varun Surya
Deepika Mishra
Rasla P C
- Publikationsdatum
- 01.12.2026
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 1/2026
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-025-01860-5
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