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15.05.2017 | Original Article

Mediators of Weight Loss Maintenance in the Keep It Off Trial

verfasst von: A.L. Crain, PhD, N.E. Sherwood, PhD, B.C. Martinson, PhD, R.W. Jeffery, PhD

Erschienen in: Annals of Behavioral Medicine

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Abstract

Background

An important step toward enhancing the efficacy of weight loss maintenance interventions is identifying the pathways through which successful interventions such as the Keep It Off trial have worked.

Purpose

This study aimed to assess the viability of mediated relationships between the Keep It Off Guided intervention, conceptually and empirically grounded potential mediators, and weight. Repeated measurement of mediators and weight enabled documentation of the temporal ordering of intervention delivery and changes in mediators and in weight among participants randomized to the Guided intervention or Self-Directed comparison group.

Methods

Total, direct, and indirect effects of the Guided intervention on weight change were calculated and tested for significance. Indirect effects were comprised of the influence of the intervention on three change scores for each mediator and the relationship between mediator changes and weight changes 6 months later.

Results

Guided intervention participants regained about 2% less weight over 24 months than Self-Directed participants. Starting daily self-weighing accounted for the largest share of this difference, followed by not stopping self-weighing.

Conclusions

Daily self-weighing mediated 24-month weight loss maintenance.

Trial Registration Number

The trial is registered with ClinicalTrials.gov (Identifier: NCT00702455 www.clinicaltrials.gov/ct2/show/NCT00702455).

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Titel: Mediators of Weight Loss Maintenance in the Keep It Off Trial
verfasst von: A.L. Crain, PhD
N.E. Sherwood, PhD
B.C. Martinson, PhD
R.W. Jeffery, PhD
Publikationsdatum: 15.05.2017
Verlag: Springer US
Erschienen in: Annals of Behavioral Medicine
Print ISSN: 0883-6612
Elektronische ISSN: 1532-4796
DOI: https://doi.org/10.1007/s12160-017-9917-x

Neu in den Fachgebieten Neurologie und Psychiatrie

23.04.2024 | Demenz | Nachrichten

Springer Medizin

Mediators of Weight Loss Maintenance in the Keep It Off Trial

Abstract

Background

Purpose

Methods

Results

Conclusions

Trial Registration Number

Neu in den Fachgebieten Neurologie und Psychiatrie

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Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

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Springer Medizin

Abstract

Background

Purpose

Methods

Results

Conclusions

Trial Registration Number

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Neu in den Fachgebieten Neurologie und Psychiatrie

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein