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Medical Molecular Morphology

Medical Molecular Morphology OnlineFirst articles

18.07.2018 | Original Paper Open Access

FGF-2 combined with bilayer artificial dermis composed of collagen matrix prompts generation of fat pad in subcutis of mice

Fibroblast growth factor (FGF)-2 induces mitogenesis, angiogenesis and adipogenesis. In this study, the adipogenesis-inducing effects of FGF-2 combined with bilayer artificial dermis in mice were evaluated. FGF-2-impregnated bilayer artificial …

10.07.2018 | Original Paper

Mucinous adenocarcinoma, gastric type of the uterine cervix: clinical features and HER2 amplification

Mucinous adenocarcinoma, gastric type (GAS) is difficult to diagnose and shows poor prognosis. Trastuzumab, an anti-human epidermal growth factor type 2 (HER2) monoclonal antibody, is effective in HER2-positive stomach cancer. The objectives of …

06.07.2018 | Original Paper

Positive correlation between the density of macrophages and T-cells in undifferentiated sarcoma

Undifferentiated sarcoma (US) is a frequent soft tissue sarcoma. Although the 10-year survival rate is around 60%, advanced US is highly resistant to chemo/radiotherapy. The tumor microenvironment (TME) is closely associated with tumor …

29.06.2018 | Original Paper

Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes

Non-alcoholic steatohepatitis (NASH) is characterized by the presence of hepatic steatosis, oxidative stress, inflammation, and hepatocyte injury with or without fibrosis. In this study, we explored the effect of APD668, a GPR119 agonist alone or …

28.06.2018 | Original Paper

Immunoreactivity patterns of tight junction proteins are useful for differential diagnosis of human salivary gland tumors

The expression pattern of tight junction proteins (TJPs) varies among organs and tumor types. In this study, we examined the immunoreactivity of claudin (CLDN)-1, -4, and -7, and JAM-A in salivary gland tumors (SGTs) by histological types and cell …

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Medical Molecular Morphology is an international forum for researchers in both basic and clinical medicine to present and discuss new research on the structural mechanisms and the processes of health and disease at the molecular level. The normal function and structures of molecules, organelles, cells, tissues, and organs determine their normal function. Disease is thus best understood in terms of structural changes in these levels of biological organization, especially in molecules and molecular interactions as well as the cellular localization of chemical components. Medical Molecular Morphology presents articles on basic or clinical research in the fields of cell biology, molecular biology, and medical, veterinary, and dental sciences using techniques for structural research such as electron microscopy, confocal laser scanning microscopy, enzyme histochemistry, immunohistochemistry, radioautography, X-ray microanalysis, and in situ hybridization.

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Neu im Fachgebiet Pathologie

27.06.2018 | Originalien | Ausgabe 4/2018

Ärztliche Konsultationen bei Verdachtsfällen von Kindeswohlgefährdung

Systematische Untersuchung in zwei Jugendamtsbezirken von Sachsen-Anhalt

26.06.2018 | Prostatakarzinom | CME | Ausgabe 4/2018

CME: Neuroendokrines Prostatakarzinom

19.06.2018 | Schwerpunkt: Pathologie und Forschungsbiobanken | Ausgabe 4/2018

Der Aufbau und Betrieb einer Zentralen Biomaterialbank

Die ZeBanC der Charité Berlin