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Erschienen in: Journal of Bioethical Inquiry 3/2018

06.07.2018 | Original Research

Medicolegal Complications of Apnoea Testing for Determination of Brain Death

verfasst von: Ariane Lewis, David Greer

Erschienen in: Journal of Bioethical Inquiry | Ausgabe 3/2018

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Abstract

Recently, there have been a number of lawsuits in the United States in which families objected to performance of apnoea testing for determination of brain death. The courts reached conflicting determinations in these cases. We discuss the medicolegal complications associated with apnoea testing that are highlighted by these cases and our position that the decision to perform apnoea testing should be made by clinicians, not families, judges, or juries.
Literatur
Zurück zum Zitat American Academy of Pediatrics, Task Force on Brain Death in Children. 1987. Guidelines for the determination of brain death in children. Pediatrics 80(2): 298–300. American Academy of Pediatrics, Task Force on Brain Death in Children. 1987. Guidelines for the determination of brain death in children. Pediatrics 80(2): 298–300.
Zurück zum Zitat An appraisal of the criteria of cerebral death. 1977. JAMA 237(10): 982–986.CrossRef An appraisal of the criteria of cerebral death. 1977. JAMA 237(10): 982–986.CrossRef
Zurück zum Zitat Bernat, J.L. 2013. Controversies in defining and determining death in critical care. Nature Reviews. Neurology 9(3): 164–173.CrossRef Bernat, J.L. 2013. Controversies in defining and determining death in critical care. Nature Reviews. Neurology 9(3): 164–173.CrossRef
Zurück zum Zitat Bracco, D., B. Bissonnette, J.B. Favre, O. Moeschler, G. Boulard, and P. Ravussin. 1997. Cerebral hemodynamics and intracranial hypertension. Annales Francaises D’anesthesie et de Reanimation 16(4): 429–434. Bracco, D., B. Bissonnette, J.B. Favre, O. Moeschler, G. Boulard, and P. Ravussin. 1997. Cerebral hemodynamics and intracranial hypertension. Annales Francaises D’anesthesie et de Reanimation 16(4): 429–434.
Zurück zum Zitat Burck, R., L. Anderson-Shaw, M. Sheldon, and E.A. Egan. 2006. The clinical response to brain death: A policy proposal. JONA’S Healthcare Law, Ethics and Regulation 8(2): 53–59.CrossRef Burck, R., L. Anderson-Shaw, M. Sheldon, and E.A. Egan. 2006. The clinical response to brain death: A policy proposal. JONA’S Healthcare Law, Ethics and Regulation 8(2): 53–59.CrossRef
Zurück zum Zitat Burkle, C.M., and J.J. Benson. 2012. End-of-life care decisions: Importance of reviewing systems and limitations after 2 recent North American cases. Mayo Clinic Proceedings 87(11): 1098–1105.CrossRef Burkle, C.M., and J.J. Benson. 2012. End-of-life care decisions: Importance of reviewing systems and limitations after 2 recent North American cases. Mayo Clinic Proceedings 87(11): 1098–1105.CrossRef
Zurück zum Zitat Burkle, C.M., A.M. Schipper, and E.F.M. Wijdicks. 2011. Brain death and the courts. Neurology 76(9): 837–841.CrossRef Burkle, C.M., A.M. Schipper, and E.F.M. Wijdicks. 2011. Brain death and the courts. Neurology 76(9): 837–841.CrossRef
Zurück zum Zitat Burkle, C.M., R.R. Sharp, and E.F. Wijdicks. 2014. Why brain death is considered death and why there should be no confusion. Neurology 83(16): 1464–1469.CrossRef Burkle, C.M., R.R. Sharp, and E.F. Wijdicks. 2014. Why brain death is considered death and why there should be no confusion. Neurology 83(16): 1464–1469.CrossRef
Zurück zum Zitat Burt, R.A. 2002. The medical futility debate: Patient choice, physician obligation, and end-of-life care. Journal of Palliative Medicine 5(2): 249–254.CrossRef Burt, R.A. 2002. The medical futility debate: Patient choice, physician obligation, and end-of-life care. Journal of Palliative Medicine 5(2): 249–254.CrossRef
Zurück zum Zitat Czosnyka, M., M. Aries, C. Weersink, et al. 2016. “Solid red line”: An observational study on death from refractory intracranial hypertension. Acta Neurochirurgica. Supplement, 122:113–116.CrossRef Czosnyka, M., M. Aries, C. Weersink, et al. 2016. “Solid red line”: An observational study on death from refractory intracranial hypertension. Acta Neurochirurgica. Supplement, 122:113–116.CrossRef
Zurück zum Zitat Datar, S., J. Fugate, A. Rabinstein, P. Couillard, and E.F.M. Wijdicks. 2014. Completing the apnea test: Decline in complications. Neurocritical Care 21(3): 392–396.CrossRef Datar, S., J. Fugate, A. Rabinstein, P. Couillard, and E.F.M. Wijdicks. 2014. Completing the apnea test: Decline in complications. Neurocritical Care 21(3): 392–396.CrossRef
Zurück zum Zitat del Carmen, M.G., and S. Joffe. 2005. “Informed consent for medical treatment and research: A Reviewreview.” The Oncologist 10 (8): 636–641.CrossRef del Carmen, M.G., and S. Joffe. 2005. “Informed consent for medical treatment and research: A Reviewreview.” The Oncologist 10 (8): 636–641.CrossRef
Zurück zum Zitat Ding, Z., Q. Zhang, J. Wu, Z. Yang, and X. Zhao. 2015. A comparison of brain death criteria between China and the United States. Chinese Medical Journal 128(21): 2896–2901.CrossRef Ding, Z., Q. Zhang, J. Wu, Z. Yang, and X. Zhao. 2015. A comparison of brain death criteria between China and the United States. Chinese Medical Journal 128(21): 2896–2901.CrossRef
Zurück zum Zitat Earnest, M.P., H.R. Beresford, and H.B. McIntyre. 1986. Testing for apnea in suspected brain death: Methods used by 129 clinicians. Neurology 36(4): 542–544.CrossRef Earnest, M.P., H.R. Beresford, and H.B. McIntyre. 1986. Testing for apnea in suspected brain death: Methods used by 129 clinicians. Neurology 36(4): 542–544.CrossRef
Zurück zum Zitat Flamm, A.L., M.L. Smith, and P.A. Mayer. 2014. Family members’ requests to extend physiologic support after declaration of brain death: A case series analysis and proposed guidelines for clinical management. The Journal of Clinical Ethics 25(3): 222–237.PubMed Flamm, A.L., M.L. Smith, and P.A. Mayer. 2014. Family members’ requests to extend physiologic support after declaration of brain death: A case series analysis and proposed guidelines for clinical management. The Journal of Clinical Ethics 25(3): 222–237.PubMed
Zurück zum Zitat Greer, D.M., H.H. Wang, J.D. Robinson, P.N. Varelas, G.V. Henderson, and E.F.M. Wijdicks. 2016. Variability of brain death policies in the United States. JAMA Neurology 73(2): 213–218.CrossRef Greer, D.M., H.H. Wang, J.D. Robinson, P.N. Varelas, G.V. Henderson, and E.F.M. Wijdicks. 2016. Variability of brain death policies in the United States. JAMA Neurology 73(2): 213–218.CrossRef
Zurück zum Zitat Hall, D.E., A.V. Prochazka, and A.S. Fink. 2012. Informed consent for clinical treatment. CMAJ: Canadian Medical Association Journal 184(5): 533–540.CrossRef Hall, D.E., A.V. Prochazka, and A.S. Fink. 2012. Informed consent for clinical treatment. CMAJ: Canadian Medical Association Journal 184(5): 533–540.CrossRef
Zurück zum Zitat Harvard Medical School, Ad Hoc Committee to Examine the Definition of Brain Death. 1968. A definition of irreversible coma. Report. JAMA 205(6): 337–340.CrossRef Harvard Medical School, Ad Hoc Committee to Examine the Definition of Brain Death. 1968. A definition of irreversible coma. Report. JAMA 205(6): 337–340.CrossRef
Zurück zum Zitat Heuer, J., M. Selke, T. Crozier, et al. 2012. Effects of acute intracranial hypertension on extracerebral organs: A randomized experimental study in pigs. Journal of Neurological Surgery Part A: Central European Neurosurgery 73(5): 289–295.CrossRef Heuer, J., M. Selke, T. Crozier, et al. 2012. Effects of acute intracranial hypertension on extracerebral organs: A randomized experimental study in pigs. Journal of Neurological Surgery Part A: Central European Neurosurgery 73(5): 289–295.CrossRef
Zurück zum Zitat Joffe, A.R., N.R. Anton, and J.P. Duff. 2010. The apnea test: Rationale, confounders, and criticism. Journal of Child Neurology 25(11): 1435–1443.CrossRef Joffe, A.R., N.R. Anton, and J.P. Duff. 2010. The apnea test: Rationale, confounders, and criticism. Journal of Child Neurology 25(11): 1435–1443.CrossRef
Zurück zum Zitat Le Roux, P., D.K. Menon, G. Citerio, et al. 2014. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care. Neurocritical Care 21 (Suppl 2): S1–S26. Le Roux, P., D.K. Menon, G. Citerio, et al. 2014. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care. Neurocritical Care 21 (Suppl 2): S1–S26.
Zurück zum Zitat Lewis, A., J. Weaver, and A. Caplan. 2017a. Portrayal of brain death in film and television. American Journal of Transplantation 17(3): 761–769.CrossRef Lewis, A., J. Weaver, and A. Caplan. 2017a. Portrayal of brain death in film and television. American Journal of Transplantation 17(3): 761–769.CrossRef
Zurück zum Zitat Lewis, A., N. Adams, A. Chopra, and M. Kirschen. 2017b. Organ Support after death by neurologic criteria in pediatric patients. Critical Care Medicine 45(9): e916–e924.CrossRef Lewis, A., N. Adams, A. Chopra, and M. Kirschen. 2017b. Organ Support after death by neurologic criteria in pediatric patients. Critical Care Medicine 45(9): e916–e924.CrossRef
Zurück zum Zitat Lewis, A., N. Adams, P. Varelas, D. Greer, and A. Caplan. 2016a. Organ support after death by neurologic criteria: Results of a survey of US neurologists. Neurology 87(8): 827–834.CrossRef Lewis, A., N. Adams, P. Varelas, D. Greer, and A. Caplan. 2016a. Organ support after death by neurologic criteria: Results of a survey of US neurologists. Neurology 87(8): 827–834.CrossRef
Zurück zum Zitat Lewis, A., K. Cahn-Fuller, and A. Caplan. 2017c. Shouldn’t dead be dead?: The search for a uniform definition of death. Journal of Law, Medicine, and Ethics 45(1): 112–128.CrossRef Lewis, A., K. Cahn-Fuller, and A. Caplan. 2017c. Shouldn’t dead be dead?: The search for a uniform definition of death. Journal of Law, Medicine, and Ethics 45(1): 112–128.CrossRef
Zurück zum Zitat Lewis, A., and D. Greer. 2017a. Rebuttal from Drs Lewis and Greer. Chest 152(4): 704–705.CrossRef Lewis, A., and D. Greer. 2017a. Rebuttal from Drs Lewis and Greer. Chest 152(4): 704–705.CrossRef
Zurück zum Zitat Lewis, A., and D. Greer. 2017b. Should informed consent be required for apnea testing in patients with suspected brain death? No. Chest 152(4): 700–702.CrossRef Lewis, A., and D. Greer. 2017b. Should informed consent be required for apnea testing in patients with suspected brain death? No. Chest 152(4): 700–702.CrossRef
Zurück zum Zitat Lewis, A., A.S. Lord, B.M. Czeisler, and A. Caplan. 2016b. Public education and misinformation on brain death in mainstream media. Clinical Transplantation 30(9): 1082–1089.CrossRef Lewis, A., A.S. Lord, B.M. Czeisler, and A. Caplan. 2016b. Public education and misinformation on brain death in mainstream media. Clinical Transplantation 30(9): 1082–1089.CrossRef
Zurück zum Zitat Lewis, A., and T.M. Pope. 2017. Physician power to declare death by neurologic criteria threatened. Neurocritical Care 26(3): 446–449.CrossRef Lewis, A., and T.M. Pope. 2017. Physician power to declare death by neurologic criteria threatened. Neurocritical Care 26(3): 446–449.CrossRef
Zurück zum Zitat Lewis, A., P. Varelas, and D. Greer. 2016c. Prolonging support after brain death: When families ask for more. Neurocritical Care 24(3): 481–487.CrossRef Lewis, A., P. Varelas, and D. Greer. 2016c. Prolonging support after brain death: When families ask for more. Neurocritical Care 24(3): 481–487.CrossRef
Zurück zum Zitat Liao, S., and S. Ito. 2010. Brain death: Ethical challenges to palliative care concepts of family care. Journal of Pain and Symptom Management 40(2): 309–313.CrossRef Liao, S., and S. Ito. 2010. Brain death: Ethical challenges to palliative care concepts of family care. Journal of Pain and Symptom Management 40(2): 309–313.CrossRef
Zurück zum Zitat Ma, P., M. Yang, Q.L. Li, et al. 2006. Study on safety of apnea test in clinical determination of brain death. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 18(5): 260–263.PubMed Ma, P., M. Yang, Q.L. Li, et al. 2006. Study on safety of apnea test in clinical determination of brain death. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 18(5): 260–263.PubMed
Zurück zum Zitat MacDougall, B.J., J.D. Robinson, L. Kappus, S.N. Sudikoff, and D.M. Greer. 2014. Simulation-based training in brain death determination. Neurocritical Care 21(3): 383–391.CrossRef MacDougall, B.J., J.D. Robinson, L. Kappus, S.N. Sudikoff, and D.M. Greer. 2014. Simulation-based training in brain death determination. Neurocritical Care 21(3): 383–391.CrossRef
Zurück zum Zitat Mathur, M., and S. Ashwal. 2015. Pediatric brain death determination. Seminars in Neurology 35(2): 116–124.CrossRef Mathur, M., and S. Ashwal. 2015. Pediatric brain death determination. Seminars in Neurology 35(2): 116–124.CrossRef
Zurück zum Zitat Mathur, M., L. Petersen, M. Stadtler, et al. 2008. Variability in pediatric brain death determination and documentation in southern California. Pediatrics 121(5): 988–993.CrossRef Mathur, M., L. Petersen, M. Stadtler, et al. 2008. Variability in pediatric brain death determination and documentation in southern California. Pediatrics 121(5): 988–993.CrossRef
Zurück zum Zitat Mejia, R.E., and M.M. Pollack. 1995. Variability in brain death determination practices in children. JAMA 274(7): 550–553.CrossRef Mejia, R.E., and M.M. Pollack. 1995. Variability in brain death determination practices in children. JAMA 274(7): 550–553.CrossRef
Zurück zum Zitat Nakagawa, T.A., S. Ashwal, M. Mathur, M. Mysore, and Committee for Determination of Brain Death in Infants and Children. 2012. Guidelines for the determination of brain death in infants and children: An update of the 1987 task force recommendations-executive summary. Annals of Neurology 71(4): 573–585.CrossRef Nakagawa, T.A., S. Ashwal, M. Mathur, M. Mysore, and Committee for Determination of Brain Death in Infants and Children. 2012. Guidelines for the determination of brain death in infants and children: An update of the 1987 task force recommendations-executive summary. Annals of Neurology 71(4): 573–585.CrossRef
Zurück zum Zitat Noth, U., F. Kotajima, R. Deichmann, R. Turner, and D.R. Corfield. 2008. Mapping of the cerebral vascular response to hypoxia and hypercapnia using quantitative perfusion MRI at 3T. NMR in Biomedicine 21(5): 464–472.CrossRef Noth, U., F. Kotajima, R. Deichmann, R. Turner, and D.R. Corfield. 2008. Mapping of the cerebral vascular response to hypoxia and hypercapnia using quantitative perfusion MRI at 3T. NMR in Biomedicine 21(5): 464–472.CrossRef
Zurück zum Zitat Nusbaum, D.M., K.M. Brady, K.K. Kibler, and R.B. Easley. 2016. Acute hypercarbia increases the lower limit of cerebral blood flow autoregulation in a porcine model. Neurological Research 38(3): 196–204.CrossRef Nusbaum, D.M., K.M. Brady, K.K. Kibler, and R.B. Easley. 2016. Acute hypercarbia increases the lower limit of cerebral blood flow autoregulation in a porcine model. Neurological Research 38(3): 196–204.CrossRef
Zurück zum Zitat Orliaguet, G.A., P. Catoire, N. Liu, L. Beydon, and F. Bonnet. 1994. Transesophageal echocardiographic assessment of left ventricular function during apnea testing for brain death. Transplantation 58(6): 655–658.CrossRef Orliaguet, G.A., P. Catoire, N. Liu, L. Beydon, and F. Bonnet. 1994. Transesophageal echocardiographic assessment of left ventricular function during apnea testing for brain death. Transplantation 58(6): 655–658.CrossRef
Zurück zum Zitat Pandey, A., P. Sahota, P. Nattanmai, and C.R. Newey. 2017. Variability in diagnosing brain death at an academic medical center. Neuroscience Journal 2017: Article ID 6017958.. Pandey, A., P. Sahota, P. Nattanmai, and C.R. Newey. 2017. Variability in diagnosing brain death at an academic medical center. Neuroscience Journal 2017: Article ID 6017958..
Zurück zum Zitat Posner, J.B., C.B. Saper, N.D. Schiff, and F. Plum. 2007. Plum and Posner’s diagnosis of stupor and coma, 4th ed. New York: Oxford University Press. Posner, J.B., C.B. Saper, N.D. Schiff, and F. Plum. 2007. Plum and Posner’s diagnosis of stupor and coma, 4th ed. New York: Oxford University Press.
Zurück zum Zitat President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. 1981. Defining death: Medical, legal and ethical issues in the determination of death. Washington D.C. President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. 1981. Defining death: Medical, legal and ethical issues in the determination of death. Washington D.C.
Zurück zum Zitat President’s Council on Bioethics. 2008. Controversies in the determination of death: A white paper by the President’s Council on Bioethics. Washington D.C. President’s Council on Bioethics. 2008. Controversies in the determination of death: A white paper by the President’s Council on Bioethics. Washington D.C.
Zurück zum Zitat Rady, M.Y., and J.L. Verheijde. 2015. The clinical determination of brain death: Practice limitations. European Journal of Neurology 22(12): e85–e85.CrossRef Rady, M.Y., and J.L. Verheijde. 2015. The clinical determination of brain death: Practice limitations. European Journal of Neurology 22(12): e85–e85.CrossRef
Zurück zum Zitat Rasmussen, M. 2005. Treatment of elevated intracranial pressure with indomethacin: Friend or foe? Acta Anaesthesiologica Scandinavica 49(3): 341–350.CrossRef Rasmussen, M. 2005. Treatment of elevated intracranial pressure with indomethacin: Friend or foe? Acta Anaesthesiologica Scandinavica 49(3): 341–350.CrossRef
Zurück zum Zitat Roth, C., W. Deinsberger, J. Kleffmann, and A. Ferbert. 2015. Intracranial pressure and cerebral perfusion pressure during apnoea testing for the diagnosis of brain death - an observational study. European Journal of Neurology 22(8): 1208–1214.CrossRef Roth, C., W. Deinsberger, J. Kleffmann, and A. Ferbert. 2015. Intracranial pressure and cerebral perfusion pressure during apnoea testing for the diagnosis of brain death - an observational study. European Journal of Neurology 22(8): 1208–1214.CrossRef
Zurück zum Zitat Roth, C., W. Deinsberger, J. Kleffmann, and A. Ferbert. 2016. Controversies about irreversible loss of brain functions and cerebral perfusion in brain death. European Journal of Neurology 23(2): e8–e8.CrossRef Roth, C., W. Deinsberger, J. Kleffmann, and A. Ferbert. 2016. Controversies about irreversible loss of brain functions and cerebral perfusion in brain death. European Journal of Neurology 23(2): e8–e8.CrossRef
Zurück zum Zitat Sebening, C., C. Hagl, G. Szabo, et al. 1995. Cardiocirculatory effects of acutely increased intracranial pressure and subsequent brain death. European Journal of Cardio-Thoracic Surgery 9(7): 360–372.CrossRef Sebening, C., C. Hagl, G. Szabo, et al. 1995. Cardiocirculatory effects of acutely increased intracranial pressure and subsequent brain death. European Journal of Cardio-Thoracic Surgery 9(7): 360–372.CrossRef
Zurück zum Zitat Shah, S.K., K. Kasper, and F.G. Miller. 2015. A narrative review of the empirical evidence on public attitudes on brain death and vital organ transplantation: The need for better data to inform policy. Journal of Medical Ethics 41(4): 291–296.CrossRef Shah, S.K., K. Kasper, and F.G. Miller. 2015. A narrative review of the empirical evidence on public attitudes on brain death and vital organ transplantation: The need for better data to inform policy. Journal of Medical Ethics 41(4): 291–296.CrossRef
Zurück zum Zitat Shemie, S.D., L. Hornby, A. Baker, et al. 2014. International guideline development for the determination of death. Intensive Care Medicine 40(6): 788–797.CrossRef Shemie, S.D., L. Hornby, A. Baker, et al. 2014. International guideline development for the determination of death. Intensive Care Medicine 40(6): 788–797.CrossRef
Zurück zum Zitat Siminoff, L.A., C. Burant, and S.J. Youngner. 2004. Death and organ procurement: Public beliefs and attitudes. Kennedy Institute of Ethics Journal 14(3): 217–234.CrossRef Siminoff, L.A., C. Burant, and S.J. Youngner. 2004. Death and organ procurement: Public beliefs and attitudes. Kennedy Institute of Ethics Journal 14(3): 217–234.CrossRef
Zurück zum Zitat Smith, M.L., and A. Lederman Flamm. 2011. Accommodating religious beliefs in the ICU: A narrative account of a disputed death. Narrative Inquiry in Bioethics 1(1): 55–64.CrossRef Smith, M.L., and A. Lederman Flamm. 2011. Accommodating religious beliefs in the ICU: A narrative account of a disputed death. Narrative Inquiry in Bioethics 1(1): 55–64.CrossRef
Zurück zum Zitat Solek-Pastuszka, J., W. Saucha, W. Iwanczuk, and R. Bohatyrewicz. 2015. Evolution of apnoea test in brain death diagnostics. Anaesthesiology Intensive Therapy. 47(4): 363–367.CrossRef Solek-Pastuszka, J., W. Saucha, W. Iwanczuk, and R. Bohatyrewicz. 2015. Evolution of apnoea test in brain death diagnostics. Anaesthesiology Intensive Therapy. 47(4): 363–367.CrossRef
Zurück zum Zitat Spike, J., and J. Greenlaw. 1995. Ethics consultation: Persistent brain death and religion: Must a person believe in death to die? Journal of Law, Medicine, and Ethics 23: 291–294.CrossRef Spike, J., and J. Greenlaw. 1995. Ethics consultation: Persistent brain death and religion: Must a person believe in death to die? Journal of Law, Medicine, and Ethics 23: 291–294.CrossRef
Zurück zum Zitat Sprung, C.L., R.D. Truog, J.R. Curtis, et al. 2014. Seeking worldwide professional consensus on the principles of end-of-life care for the critically ill. The consensus for worldwide end-of-life practice for patients in intensive care units (WELPICUS) study. American Journal of Respiratory and Critical Care Medicine 190(8): 855–866.CrossRef Sprung, C.L., R.D. Truog, J.R. Curtis, et al. 2014. Seeking worldwide professional consensus on the principles of end-of-life care for the critically ill. The consensus for worldwide end-of-life practice for patients in intensive care units (WELPICUS) study. American Journal of Respiratory and Critical Care Medicine 190(8): 855–866.CrossRef
Zurück zum Zitat Tibballs, J. 2010. A critique of the apneic oxygenation test for the diagnosis of “brain death” Pediatric Critical Care Medicine 11(4): 475–478.PubMed Tibballs, J. 2010. A critique of the apneic oxygenation test for the diagnosis of “brain death” Pediatric Critical Care Medicine 11(4): 475–478.PubMed
Zurück zum Zitat Truog, R.D., and R.C Tasker. 2017. Counterpoint: “Should informed consent be required for apnea testing in patients with suspected brain death?” Yes. Chest 152(4): 702–704.CrossRef Truog, R.D., and R.C Tasker. 2017. Counterpoint: “Should informed consent be required for apnea testing in patients with suspected brain death?” Yes. Chest 152(4): 702–704.CrossRef
Zurück zum Zitat Wahlster, S., E.F.M. Wijdicks, P.V. Patel, et al. 2015. Brain death declaration: Practices and perceptions worldwide. Neurology 84(18): 1870–1879.CrossRef Wahlster, S., E.F.M. Wijdicks, P.V. Patel, et al. 2015. Brain death declaration: Practices and perceptions worldwide. Neurology 84(18): 1870–1879.CrossRef
Zurück zum Zitat Wijdicks, E.F.M. 1995. Determining brain death in adults. Neurology 45(5): 1003–1011.CrossRef Wijdicks, E.F.M. 1995. Determining brain death in adults. Neurology 45(5): 1003–1011.CrossRef
Zurück zum Zitat Wijdicks, E.F.M., A.A. Rabinstein, E.M. Manno, and J.D. Atkinson. 2008. Pronouncing brain death: Contemporary practice and safety of the apnea test. Neurology 71(16): 1240–1244.CrossRef Wijdicks, E.F.M., A.A. Rabinstein, E.M. Manno, and J.D. Atkinson. 2008. Pronouncing brain death: Contemporary practice and safety of the apnea test. Neurology 71(16): 1240–1244.CrossRef
Zurück zum Zitat Wijdicks, E.F.M., P.N. Varelas, G.S. Gronseth, and D.M. Greer. 2010. Evidence-based guideline update: Determining brain death in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 74(23): 1911–1918.CrossRef Wijdicks, E.F.M., P.N. Varelas, G.S. Gronseth, and D.M. Greer. 2010. Evidence-based guideline update: Determining brain death in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 74(23): 1911–1918.CrossRef
Zurück zum Zitat Wu, X., Q. Fang, L. Li, Y. Qiu, and B. Luo. 2008. Complications associated with the apnea test in the determination of the brain death. Chinese Medical Journal 121(13): 1169–1172.PubMed Wu, X., Q. Fang, L. Li, Y. Qiu, and B. Luo. 2008. Complications associated with the apnea test in the determination of the brain death. Chinese Medical Journal 121(13): 1169–1172.PubMed
Zurück zum Zitat Yang, X., W. Liu, H. Shen, et al. 2005. Correlation of cell apoptosis with brain edema and elevated intracranial pressure in traumatic brain injury. Chinese Journal of Traumatology 8(2): 96–100.PubMed Yang, X., W. Liu, H. Shen, et al. 2005. Correlation of cell apoptosis with brain edema and elevated intracranial pressure in traumatic brain injury. Chinese Journal of Traumatology 8(2): 96–100.PubMed
Metadaten
Titel
Medicolegal Complications of Apnoea Testing for Determination of Brain Death
verfasst von
Ariane Lewis
David Greer
Publikationsdatum
06.07.2018
Verlag
Springer Singapore
Erschienen in
Journal of Bioethical Inquiry / Ausgabe 3/2018
Print ISSN: 1176-7529
Elektronische ISSN: 1872-4353
DOI
https://doi.org/10.1007/s11673-018-9863-8

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