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European Journal of Nutrition

Erschienen in:

10.01.2022 | Review

Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies

verfasst von: Sheida Zeraattalab-Motlagh, Ahmad Jayedi, Sakineh Shab-Bidar

Erschienen in: European Journal of Nutrition | Ausgabe 4/2022

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Abstract

Purpose

Previous meta-analyses assessed the association of adherence to the Mediterranean dietary pattern (MedDiet) with the risk of type 2 diabetes (T2D). Since then, new large-scale cohort studies have been published. In addition, dose–response relation was not previously investigated and the certainty of evidence was not assessed. We aimed to explore the dose–response relationship between adherence to the MedDiet and the risk of T2D.

Methods

We did a systematic search using PubMed, Scopus, and ISI Web of Science upto April 2021 for prospective cohort studies of the relationship between adherence to the MedDiet and the risk of T2D in the general population. The summary relative risks (RR) and 95%CI were estimated by applying a random-effects model.

Results

Fourteen prospective cohort studies (410,303 participants and 41,466 cases) were included. There was an inverse association for the highest versus lowest category of adherence to the MedDiet (RR: 0.79, 95%CI 0.72, 0.88; I² = 82%, n = 14; Risk difference: – 21 per 1000 person, 95%CI – 28, – 12; GRADE = moderate certainty), and for a 2-point increment in the MedDiet adherence score (RR: 0.86, 95%CI 0.82, 0.91; n = 13). The RR remained significant after controlling for important confounders and in almost all subgroups, especially subgroups defined by geographical region. We observed an inverse linear association between MedDiet adherence score and T2D incidence.

Conclusion

Adherence to the MedDiet was inversely related to T2D risk in a dose–response manner. Adherence to a Mediterranean-style diet may be a good advice for the primary prevention of T2D.

Registry and registry number

PROSPERO (CRD42021246589).

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Titel: Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies
verfasst von: Sheida Zeraattalab-Motlagh
Ahmad Jayedi
Sakineh Shab-Bidar
Publikationsdatum: 10.01.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nutrition / Ausgabe 4/2022
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-021-02761-3

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Thermische Verletzungen gehören zu den schwerwiegendsten Traumen und hinterlassen oft langfristige körperliche und psychische Spuren. Die aktuelle S2k-Leitlinie „Behandlung thermischer Verletzungen im Kindesalter (Verbrennung, Verbrühung)“ bietet eine strukturierte Übersicht über das empfohlene Vorgehen.

EKG Essentials: EKG befunden mit System (Link öffnet in neuem Fenster)

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Update Innere Medizin

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Springer Medizin

Mediterranean dietary pattern and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis of prospective cohort studies

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Weitere Artikel der Ausgabe 4/2022

Differential impact of cold and hot tea extracts on tyrosine phosphatases regulating insulin receptor activity: a focus on PTP1B and LMW-PTP

Serum n-6 polyunsaturated fatty acids and risk of atrial fibrillation: the Kuopio Ischaemic Heart Disease Risk Factor Study

Screening for anti-adipogenic, pro-lipolytic and thermogenic plant extracts by models associating intestinal epithelial cells with human adipose cells

Effects of changing from a diet with saturated fat to a diet with n-6 polyunsaturated fat on the serum metabolome in relation to cardiovascular disease risk factors

Revised D-A-CH reference values for the intake of biotin

Human milk fatty acid composition and its association with maternal blood and adipose tissue fatty acid content in a cohort of women from Europe

Kompaktes Leitlinien-Wissen Innere Medizin (Link öffnet in neuem Fenster)

Neu im Fachgebiet Innere Medizin

Chemoembolisation bei HCC frühzeitig mit Checkpoint-Inhibitor kombinieren?

Antikörper-Wirkstoff-Konjugat hält Brusttumoren langfristig in Schach

Studie zur HIFU bei Prostatakrebs lässt viele Fragen offen

Leitlinienkonformes Management thermischer Verletzungen

EKG Essentials: EKG befunden mit System (Link öffnet in neuem Fenster)

Update Innere Medizin

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Registry and registry number

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