Erschienen in:
05.02.2018 | Case Report
Medulloblastoma in association with sacral agenesis; a case report
verfasst von:
Zahra Ebrahim Soltani, Zohreh Habibi, Farideh Nejat
Erschienen in:
Child's Nervous System
|
Ausgabe 6/2018
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Abstract
Medulloblastoma is a congenital brain tumor which can be associated with different congenital anomalies. However, coincidence of cerebellar medulloblastoma with sacral agenesis has not been reported so far. A variety of genetic and/or environmental predisposing factors have been proposed for both diseases. Herein, an unprecedented coincidence of these two conditions is presented. A neonate was born with lumbosacral agenesis, paraplegia, and atrophic legs, and he developed medulloblastoma with three ventricular hydrocephalus 3 years later. Different aspects regarding the embryology and etiology of both ailments are discussed, assuming the possibility that the same genetic and/or environmental risk factors may have played a part in both conditions.