Erschienen in:
26.06.2018 | Melanomas
MelMART Trial: It’s Now or Never
verfasst von:
Daniel Coit, MD, Charlotte Ariyan, MD, PhD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 9/2018
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Excerpt
Local recurrence after resection of cancer can be a result of many factors, including bad tumor biology, inadequate surgical margins, and lack of effective adjuvant treatments. Removing all macroscopic disease remains a basic tenet of surgical oncology. However, the importance of removing additional “normal” tissue beyond the tumor continues to evolve. Careful studies of the widest surgical margins, amputation for sarcoma, or mastectomy for breast cancer have failed to completely eliminate the risk of local recurrence or to improve long-term survival when a less radical option was available. …