Skip to main content
Erschienen in: Journal of Cancer Survivorship 4/2010

01.12.2010

Mental health among young adult survivors of childhood cancer and their siblings including posttraumatic growth

verfasst von: Kiyoko Kamibeppu, Iori Sato, Misato Honda, Shuichi Ozono, Naoko Sakamoto, Tsuyako Iwai, Jun Okamura, Keiko Asami, Naoko Maeda, Hiroko Inada, Naoko Kakee, Keizo Horibe, Yasushi Ishida

Erschienen in: Journal of Cancer Survivorship | Ausgabe 4/2010

Einloggen, um Zugang zu erhalten

Abstract

Background

Few studies have addressed the mental health status of young adult childhood cancer survivors (CCSs) and their siblings (SIBs). This paper focuses on depression, anxiety, posttraumatic stress symptoms (PTSS), and posttraumatic growth (PTG) among Japanese CCSs and their SIBs.

Methods

Adolescent and young adult CCSs (n = 185), in remission for more than 1 year, their SIBs (n = 72), and general controls (CONTs) (n = 1,000) completed anonymous self-report questionnaires for depression, anxiety, PTSS, and PTG. The physicians in charge also completed an anonymous disease/treatment data sheet.

Results

CCSs were approximately 8 years old at diagnosis and approximately 23 years old at the time of the survey. Their diagnoses included leukemia (57%), lymphoma (12%), and solid tumors (30%). Thirty-eight percent underwent surgery and 25% received stem cell transplantation. No significant differences were found between CCSs and CONTs in terms of depression and anxiety. CCSs had significantly more PTSS and had remarkably greater PTG compared to CONTs. Although no significant differences were found between SIBs and CONTs regarding depression, anxiety, or PTSS, female SIBs exhibited greater PTG compared to female CONTs.

Conclusion

To empower CCSs, they should be evaluated periodically regarding PTSS and PTG and should be provided appropriate care and feedback. The fact that the mental health status of young adult SIBs was similar to CONTs at 15 years after their siblings’ diagnoses may help reassure parents who worry about mental health among the siblings of an affected child during and after his/her treatment.
Literatur
1.
Zurück zum Zitat Homer MJ, Ries LAG, Krapcho M, Neyman N, Aminou R, Howlader N, et al. editors. SEER Cancer Statistics Review, 1975–2006, National Cancer Institute. [based on November 2008 SEER data submission, posted to the SEER web site], 2009. Available from: http://seer.cancer.gov/csr/1975_2006/. Homer MJ, Ries LAG, Krapcho M, Neyman N, Aminou R, Howlader N, et al. editors. SEER Cancer Statistics Review, 1975–2006, National Cancer Institute. [based on November 2008 SEER data submission, posted to the SEER web site], 2009. Available from: http://​seer.​cancer.​gov/​csr/​1975_​2006/​.
2.
Zurück zum Zitat Oeffinger K, Eshelman D. Transition issues. In: Schwartz CL, Hobbie WL, Constine LS, Ruccione KS, editors. Survivors of childhood and adolescent cancer; a multidisciplinary approach. 2nd ed. Berlin: Springer; 2005. p. 333–43. Oeffinger K, Eshelman D. Transition issues. In: Schwartz CL, Hobbie WL, Constine LS, Ruccione KS, editors. Survivors of childhood and adolescent cancer; a multidisciplinary approach. 2nd ed. Berlin: Springer; 2005. p. 333–43.
3.
Zurück zum Zitat Ganz P. Pediatric cancer survivorship: the childhood cancer survivor study. J Clin Oncol. 2009;27(14):2307–414.CrossRefPubMed Ganz P. Pediatric cancer survivorship: the childhood cancer survivor study. J Clin Oncol. 2009;27(14):2307–414.CrossRefPubMed
4.
Zurück zum Zitat Hawkins M, Lancashire E, Winter D, Frobisher C, Reulen R, Taylor A, et al. The British childhood cancer survivor study: objectives, methods, population structure, response rates and initial descriptive information. Pediatr Blood Cancer. 2008;50(5):1018–25.CrossRefPubMed Hawkins M, Lancashire E, Winter D, Frobisher C, Reulen R, Taylor A, et al. The British childhood cancer survivor study: objectives, methods, population structure, response rates and initial descriptive information. Pediatr Blood Cancer. 2008;50(5):1018–25.CrossRefPubMed
5.
Zurück zum Zitat Horibe K, Tsuchida M, Tsurusawa M, Nakahata T. The realities of the medical system for pediatric hematologic malignancies in Japan. J Jpn Pediatr Soc. 2009;113(1):105–11 (Abstract in English). Horibe K, Tsuchida M, Tsurusawa M, Nakahata T. The realities of the medical system for pediatric hematologic malignancies in Japan. J Jpn Pediatr Soc. 2009;113(1):105–11 (Abstract in English).
6.
Zurück zum Zitat Kaneko Y, Matsushita T. Revealing a true diagnosis, informed consent, and palliative care in cancer children; a questionnaire to Japanese pediatric oncologists. J Jpn Pediatr Soc. 1995;99(2):534–9 (Abstract in English). Kaneko Y, Matsushita T. Revealing a true diagnosis, informed consent, and palliative care in cancer children; a questionnaire to Japanese pediatric oncologists. J Jpn Pediatr Soc. 1995;99(2):534–9 (Abstract in English).
7.
Zurück zum Zitat Ishida Y, Hongo T, Kohdera U, Hori H, Aoyanagi N, Inada H, et al. There is much variation among the hospitals in some factors which influence QOL during leukemia treatment. Jpn J Pediatr Oncol. 2003;40(1):53–9 (in Japanese). Ishida Y, Hongo T, Kohdera U, Hori H, Aoyanagi N, Inada H, et al. There is much variation among the hospitals in some factors which influence QOL during leukemia treatment. Jpn J Pediatr Oncol. 2003;40(1):53–9 (in Japanese).
8.
Zurück zum Zitat Ishida Y. Long-term follow-up for childhood cancer survivors. Japanese Journal of Pediatric Hematology. 2008;22(3):144–55 (Abstract in English). Ishida Y. Long-term follow-up for childhood cancer survivors. Japanese Journal of Pediatric Hematology. 2008;22(3):144–55 (Abstract in English).
9.
Zurück zum Zitat Ishida Y, Honda M, Kamibeppu K, Ozono S, Iwai T, Kakee N, et al. Cross-sectional survey on the late effects and QOL of childhood cancer survivors Part 1: Research methods and subjects. J Jpn Pediatr Soc. 2010;114(4) (Abstract in English) (in press). Ishida Y, Honda M, Kamibeppu K, Ozono S, Iwai T, Kakee N, et al. Cross-sectional survey on the late effects and QOL of childhood cancer survivors Part 1: Research methods and subjects. J Jpn Pediatr Soc. 2010;114(4) (Abstract in English) (in press).
10.
Zurück zum Zitat Robison L, Mertens A, Boice J, Breslow N, Donaldson S, Green D, et al. Study design and cohort characteristics of the childhood cancer survivor study: a multi-institutional collaborative project. Med Pediatr Oncol. 2002;38(4):229–39.CrossRefPubMed Robison L, Mertens A, Boice J, Breslow N, Donaldson S, Green D, et al. Study design and cohort characteristics of the childhood cancer survivor study: a multi-institutional collaborative project. Med Pediatr Oncol. 2002;38(4):229–39.CrossRefPubMed
11.
Zurück zum Zitat Zeltzer LK, Recklitis C, Buchbinder D, Zebrack B, Casillas J, Tsao JCI, et al. Psychological status in childhood cancer survivors: a report from the childhood cancer survivors study. J Clin Oncol. 2009;27(14):2396–404.CrossRefPubMed Zeltzer LK, Recklitis C, Buchbinder D, Zebrack B, Casillas J, Tsao JCI, et al. Psychological status in childhood cancer survivors: a report from the childhood cancer survivors study. J Clin Oncol. 2009;27(14):2396–404.CrossRefPubMed
12.
Zurück zum Zitat Reulen RC, Winter DL, Lancashire ER, Zeegers MP, Jenney ME, Walters SJ, et al. Health-status of adult survivors of childhood cancer: a large-scale population-based study from the British childhood cancer survivor study. Int J Cancer. 2007;121:633–40.CrossRefPubMed Reulen RC, Winter DL, Lancashire ER, Zeegers MP, Jenney ME, Walters SJ, et al. Health-status of adult survivors of childhood cancer: a large-scale population-based study from the British childhood cancer survivor study. Int J Cancer. 2007;121:633–40.CrossRefPubMed
13.
Zurück zum Zitat Rourke MT, Kazak AE. Psychological aspects of long-term survivorship. In: Schwartz CL, Hobbie WL, Constine LS, Ruccione KS, editors. Survivors of childhood and adolescent cancer; a multidisciplinary approach. 2nd ed. Berlin: Springer; 2005. p. 295–304. Rourke MT, Kazak AE. Psychological aspects of long-term survivorship. In: Schwartz CL, Hobbie WL, Constine LS, Ruccione KS, editors. Survivors of childhood and adolescent cancer; a multidisciplinary approach. 2nd ed. Berlin: Springer; 2005. p. 295–304.
14.
Zurück zum Zitat Barakat L, Alderfer M, Kazak A. Posttraumatic growth in adolescent survivors of cancer and their mothers and fathers. J Pediatr Psychol. 2006;31(4):413–9.CrossRefPubMed Barakat L, Alderfer M, Kazak A. Posttraumatic growth in adolescent survivors of cancer and their mothers and fathers. J Pediatr Psychol. 2006;31(4):413–9.CrossRefPubMed
15.
Zurück zum Zitat Asukai N, Kato H, Kawamura N, Kim Y, Yamamoto K, Kishimoto J, et al. Reliability and validity of the Japanese-language version of the impact of event scale-revised (IES-R-J): four studies of different traumatic events. J Nerv Ment Dis. 2002;190:175–82.CrossRefPubMed Asukai N, Kato H, Kawamura N, Kim Y, Yamamoto K, Kishimoto J, et al. Reliability and validity of the Japanese-language version of the impact of event scale-revised (IES-R-J): four studies of different traumatic events. J Nerv Ment Dis. 2002;190:175–82.CrossRefPubMed
16.
Zurück zum Zitat Taku K, Calhoun L, Tedeschi R, Gil-Rivas V, Kilmer R, Cann A. Examining posttraumatic growth among Japanese university students. Anxiety Stress Coping. 2007;20(4):353–67.CrossRefPubMed Taku K, Calhoun L, Tedeschi R, Gil-Rivas V, Kilmer R, Cann A. Examining posttraumatic growth among Japanese university students. Anxiety Stress Coping. 2007;20(4):353–67.CrossRefPubMed
17.
Zurück zum Zitat Tedeschi R, Calhoun L. The posttraumatic growth inventory: measuring the positive legacy of trauma. J Trauma Stress. 1996;9(3):455–71.CrossRefPubMed Tedeschi R, Calhoun L. The posttraumatic growth inventory: measuring the positive legacy of trauma. J Trauma Stress. 1996;9(3):455–71.CrossRefPubMed
18.
Zurück zum Zitat Hudson M, Hester A, Sweeney T, Kippenbrock S, Majcina R, Vear S, et al. A model of care for childhood cancer survivors that facilitates research. J Pediatr Oncol Nurs. 2004;21(3):170–4.CrossRefPubMed Hudson M, Hester A, Sweeney T, Kippenbrock S, Majcina R, Vear S, et al. A model of care for childhood cancer survivors that facilitates research. J Pediatr Oncol Nurs. 2004;21(3):170–4.CrossRefPubMed
19.
Zurück zum Zitat Kessler R, Andrews G, Colpe L, Hiripi E, Mroczek D, Normand S, et al. Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med. 2002;32(6):959–76.CrossRefPubMed Kessler R, Andrews G, Colpe L, Hiripi E, Mroczek D, Normand S, et al. Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med. 2002;32(6):959–76.CrossRefPubMed
20.
Zurück zum Zitat Furukawa TA, Kawakami N, Saitoh M, Ono Y, Nakane Y, Nakamura Y, et al. The performance of the Japanese version of the K6 and K10 in the world mental health survey Japan. Int J Methods Psychiatr Res. 2008;17(3):152–8.CrossRefPubMed Furukawa TA, Kawakami N, Saitoh M, Ono Y, Nakane Y, Nakamura Y, et al. The performance of the Japanese version of the K6 and K10 in the world mental health survey Japan. Int J Methods Psychiatr Res. 2008;17(3):152–8.CrossRefPubMed
21.
Zurück zum Zitat American Psychiatric Association. Quick reference to the diagnostic criteria from DSM-IV. Washington DC: American Psychiatric Association; 1994. American Psychiatric Association. Quick reference to the diagnostic criteria from DSM-IV. Washington DC: American Psychiatric Association; 1994.
22.
Zurück zum Zitat Weiss DS, Marner CR. The impact of the event scale-revised. In: Wilson JP, Keane TM, editors. Assessing psychological trauma and PTSD: a practitioner’s handbook. New York: Guilford; 1997. p. 399–411. Weiss DS, Marner CR. The impact of the event scale-revised. In: Wilson JP, Keane TM, editors. Assessing psychological trauma and PTSD: a practitioner’s handbook. New York: Guilford; 1997. p. 399–411.
23.
Zurück zum Zitat Taku K. The mechanisms at work in self-growth coming from stress experience: concentrating on making meaning out of stress [abstract in English]. Journal of Japanese Clinical Psychology. 2005;23(2):161–72. Taku K. The mechanisms at work in self-growth coming from stress experience: concentrating on making meaning out of stress [abstract in English]. Journal of Japanese Clinical Psychology. 2005;23(2):161–72.
24.
Zurück zum Zitat Weiss DS. The impact of the event scale-revised. In: Wilson JP, Keane TM, editors. Assessing psychological trauma and PTSD. 2nd ed. New York: Guilford; 2004. p. 168–89. Weiss DS. The impact of the event scale-revised. In: Wilson JP, Keane TM, editors. Assessing psychological trauma and PTSD. 2nd ed. New York: Guilford; 2004. p. 168–89.
25.
Zurück zum Zitat Zebrack B, Zeltzer L, Whitton J, Mertens A, Odom L, Berkow R, et al. Psychological outcomes in long-term survivors of childhood leukemia, Hodgkin’s disease, and non-Hodgkin’s lymphoma: a report from the childhood cancer survivor study. Pediatrics. 2002;110(1):42–52.CrossRefPubMed Zebrack B, Zeltzer L, Whitton J, Mertens A, Odom L, Berkow R, et al. Psychological outcomes in long-term survivors of childhood leukemia, Hodgkin’s disease, and non-Hodgkin’s lymphoma: a report from the childhood cancer survivor study. Pediatrics. 2002;110(1):42–52.CrossRefPubMed
26.
Zurück zum Zitat Zebrack B, Gurney J, Oeffinger K, Whitton J, Packer R, Mertens A, et al. Psychological outcomes in long-term survivors of childhood brain cancer: a report from the childhood cancer survivor study. J Clin Oncol. 2004;22(6):999–1006.CrossRefPubMed Zebrack B, Gurney J, Oeffinger K, Whitton J, Packer R, Mertens A, et al. Psychological outcomes in long-term survivors of childhood brain cancer: a report from the childhood cancer survivor study. J Clin Oncol. 2004;22(6):999–1006.CrossRefPubMed
27.
Zurück zum Zitat Zebrack B, Zevon M, Turk N, Nagarajan R, Whitton J, Robison L, et al. Psychological distress in long-term survivors of solid tumors diagnosed in childhood: a report from the childhood cancer survivor study. Pediatr Blood Cancer. 2007;49(1):47–51.CrossRefPubMed Zebrack B, Zevon M, Turk N, Nagarajan R, Whitton J, Robison L, et al. Psychological distress in long-term survivors of solid tumors diagnosed in childhood: a report from the childhood cancer survivor study. Pediatr Blood Cancer. 2007;49(1):47–51.CrossRefPubMed
28.
Zurück zum Zitat Hobbie W, Stuber M, Meeske K, Wissler K, Rourke M, Ruccione K, et al. Symptoms of posttraumatic stress in young adult survivors of childhood cancer. J Clin Oncol. 2000;18(24):4060–6.PubMed Hobbie W, Stuber M, Meeske K, Wissler K, Rourke M, Ruccione K, et al. Symptoms of posttraumatic stress in young adult survivors of childhood cancer. J Clin Oncol. 2000;18(24):4060–6.PubMed
29.
Zurück zum Zitat Erickson S, Steiner H. Trauma spectrum adaptation; somatic symptoms in long-term pediatric cancer survivors. Psychosomatics. 2000;41(4):339–46.CrossRefPubMed Erickson S, Steiner H. Trauma spectrum adaptation; somatic symptoms in long-term pediatric cancer survivors. Psychosomatics. 2000;41(4):339–46.CrossRefPubMed
30.
Zurück zum Zitat Erickson S, Steiner H. Trauma and personality correlates in long term pediatric cancer survivors. Child Psychiatry Hum Dev. 2001;31(3):195–213.CrossRefPubMed Erickson S, Steiner H. Trauma and personality correlates in long term pediatric cancer survivors. Child Psychiatry Hum Dev. 2001;31(3):195–213.CrossRefPubMed
31.
Zurück zum Zitat Meeske K, Ruccione K, Globe D, Stuber M. Posttraumatic stress, quality of life, and psychological distress in young adult survivors of childhood cancer. Oncol Nurs Forum. 2001;28(3):481–9.PubMed Meeske K, Ruccione K, Globe D, Stuber M. Posttraumatic stress, quality of life, and psychological distress in young adult survivors of childhood cancer. Oncol Nurs Forum. 2001;28(3):481–9.PubMed
32.
Zurück zum Zitat Kazak A, Barakat L, Alderfer M, Rourke M, Meeske K, Gallagher P, et al. Posttraumatic stress in survivors of childhood cancer and their mothers: development and validation of the impact of traumatic stressors interview schedule (ITSS). J Clin Psychol Med Settings. 2001;8(4):307–23.CrossRef Kazak A, Barakat L, Alderfer M, Rourke M, Meeske K, Gallagher P, et al. Posttraumatic stress in survivors of childhood cancer and their mothers: development and validation of the impact of traumatic stressors interview schedule (ITSS). J Clin Psychol Med Settings. 2001;8(4):307–23.CrossRef
33.
Zurück zum Zitat Langeveld N, Grootenhuis M, Voûte P, de Haan R. Posttraumatic stress symptoms in adult survivors of childhood cancer. Pediatr Blood Cancer. 2004;42(7):604–10.CrossRefPubMed Langeveld N, Grootenhuis M, Voûte P, de Haan R. Posttraumatic stress symptoms in adult survivors of childhood cancer. Pediatr Blood Cancer. 2004;42(7):604–10.CrossRefPubMed
34.
Zurück zum Zitat Schwartz L, Droter D. Posttraumatic stress and related impairment in survivors of childhood cancer in early adulthood compared to healthy peers. J Pediatr Psychol. 2006;31(4):356–66.CrossRefPubMed Schwartz L, Droter D. Posttraumatic stress and related impairment in survivors of childhood cancer in early adulthood compared to healthy peers. J Pediatr Psychol. 2006;31(4):356–66.CrossRefPubMed
35.
Zurück zum Zitat Rourke M, Hobbie W, Schwartz L, Kazak A. Posttraumatic stress disorder (PTSD) in young adult survivors of childhood cancer. Pediatr Blood Cancer. 2007;49(2):177–82.CrossRefPubMed Rourke M, Hobbie W, Schwartz L, Kazak A. Posttraumatic stress disorder (PTSD) in young adult survivors of childhood cancer. Pediatr Blood Cancer. 2007;49(2):177–82.CrossRefPubMed
36.
Zurück zum Zitat Horowitz M, Wilner N, Alvarez W. Impact of event scale: a measure of subjective stress. Psychosom Med. 1979;41(3):209–18.PubMed Horowitz M, Wilner N, Alvarez W. Impact of event scale: a measure of subjective stress. Psychosom Med. 1979;41(3):209–18.PubMed
37.
Zurück zum Zitat Kamibeppu K. Childhood illness related PTSD and preventive intervention. Japanese Journal of Child Nursing. 2005;28(9):1233–9 (in Japanese). Kamibeppu K. Childhood illness related PTSD and preventive intervention. Japanese Journal of Child Nursing. 2005;28(9):1233–9 (in Japanese).
38.
Zurück zum Zitat Calhoun LG, Tedeschi RG. Facilitating posttraumatic growth: a clinician’s guide. Mahwah: Erlbaum; 1999. Calhoun LG, Tedeschi RG. Facilitating posttraumatic growth: a clinician’s guide. Mahwah: Erlbaum; 1999.
39.
Zurück zum Zitat Mattsson E, Lindgren B, Von Essen L. Are there any positive consequences of childhood cancer? A review of the literature. Acta Oncol. 2008;47:199–206.CrossRefPubMed Mattsson E, Lindgren B, Von Essen L. Are there any positive consequences of childhood cancer? A review of the literature. Acta Oncol. 2008;47:199–206.CrossRefPubMed
40.
Zurück zum Zitat Phipps S, Long AM, Ogden J. Benefit finding scale for children: preliminary findings from a childhood cancer population. J Pediatr Psychol. 2007;32(10):1264–71.CrossRefPubMed Phipps S, Long AM, Ogden J. Benefit finding scale for children: preliminary findings from a childhood cancer population. J Pediatr Psychol. 2007;32(10):1264–71.CrossRefPubMed
41.
Zurück zum Zitat Currier JM, Hermes S, Phipps S. Brief report: children’s response to serious illness: perceptions of benefit and burden in a pediatric cancer population. J Pediatr Psychol. 2009;34(10):1129–34.CrossRefPubMed Currier JM, Hermes S, Phipps S. Brief report: children’s response to serious illness: perceptions of benefit and burden in a pediatric cancer population. J Pediatr Psychol. 2009;34(10):1129–34.CrossRefPubMed
42.
Zurück zum Zitat Stanton AL, Bower JE, Low CA. Posttraumatic growth after cancer. In: Calhoun LG, Tedeschi RG, editors. Handbook of posttraumatic growth: research and practice. 1st ed. Mahwah: Erlbaum; 2006. p. 138–75. Stanton AL, Bower JE, Low CA. Posttraumatic growth after cancer. In: Calhoun LG, Tedeschi RG, editors. Handbook of posttraumatic growth: research and practice. 1st ed. Mahwah: Erlbaum; 2006. p. 138–75.
43.
Zurück zum Zitat Cordova M, Cunningham L, Carlson C, Andrykowski M. Posttraumatic growth following breast cancer: a controlled comparison study. Health Psychol. 2001;20(3):176–85.CrossRefPubMed Cordova M, Cunningham L, Carlson C, Andrykowski M. Posttraumatic growth following breast cancer: a controlled comparison study. Health Psychol. 2001;20(3):176–85.CrossRefPubMed
44.
Zurück zum Zitat Weiss T. Posttraumatic growth in women with breast cancer and their husbands: an intersubjective validation study. J Psychosoc Oncol. 2002;20(2):65–80.CrossRef Weiss T. Posttraumatic growth in women with breast cancer and their husbands: an intersubjective validation study. J Psychosoc Oncol. 2002;20(2):65–80.CrossRef
Metadaten
Titel
Mental health among young adult survivors of childhood cancer and their siblings including posttraumatic growth
verfasst von
Kiyoko Kamibeppu
Iori Sato
Misato Honda
Shuichi Ozono
Naoko Sakamoto
Tsuyako Iwai
Jun Okamura
Keiko Asami
Naoko Maeda
Hiroko Inada
Naoko Kakee
Keizo Horibe
Yasushi Ishida
Publikationsdatum
01.12.2010
Verlag
Springer US
Erschienen in
Journal of Cancer Survivorship / Ausgabe 4/2010
Print ISSN: 1932-2259
Elektronische ISSN: 1932-2267
DOI
https://doi.org/10.1007/s11764-010-0124-z

Weitere Artikel der Ausgabe 4/2010

Journal of Cancer Survivorship 4/2010 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.