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11.06.2019 | Original Article

Metabolic and muscular factors limiting aerobic exercise in obese subjects

verfasst von: Filippo Vaccari, Mirco Floreani, Gabriella Tringali, Roberta De Micheli, Alessandro Sartorio, Stefano Lazzer

Erschienen in: European Journal of Applied Physiology | Ausgabe 8/2019

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Abstract

Purpose

The aim of the present study was to understand the role of central (cardiovascular O₂ delivery) and peripheral factors (muscle level) in limiting the maximal aerobic performance in obese (OB) subjects.

Methods

Fifteen OB (mean age ± SD 25 ± 7 years; BMI 43 ± 7 kg/m²) and 13 lean sedentary subjects (CTRL, age 27 ± 7 years; BMI 22 ± 3 kg/m²) participated in this study. Oxygen uptake (VO₂), hearth rate (HR) and cardiac output (CO) were measured during cycle ergometer (CE) and knee extension (KE) incremental tests. Maximal voluntary contractions (MVCs) of knee extensor muscles were performed before and immediately after the two tests.

Results

VO₂peak, HR peak and CO peak were significantly higher in CE than KE (+ 126%, + 33% and + 46%, respectively, p < 0.001), both in OB and CTRL subjects, without differences between the two subgroups. Maximal work rate was lower in OB than CTRL (191 ± 38 vs 226 ± 39 W, p < 0.05) in CE, while it was similar between the two subgroups in KE. Although CE and KE determined a reduction of MVC in both subgroups, MVC resulted less decreased after CE than KE exercises (− 14 vs − 32%, p < 0.001) in OB, while MVC decrements were similar after the two exercises in CTRL (− 26% vs − 30%, p > 0.05, for CE and KE, respectively).

Conclusions

The lower muscle fatigue observed in OB after CE compared to KE test suggests that central factors could be the most important limiting factor during cycling in OB.

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Titel: Metabolic and muscular factors limiting aerobic exercise in obese subjects
verfasst von: Filippo Vaccari
Mirco Floreani
Gabriella Tringali
Roberta De Micheli
Alessandro Sartorio
Stefano Lazzer
Publikationsdatum: 11.06.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Applied Physiology / Ausgabe 8/2019
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-019-04167-w

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Abstract

Purpose

Methods

Results

Conclusions

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