Skip to main content
Erschienen in: Surgical Endoscopy 12/2020

01.12.2020

Metabolic effects and outcomes of sleeve gastrectomy and gastric bypass: a cohort study

verfasst von: B. Calvo, J. A. Gracia, M. A. Bielsa, M. Martínez

Erschienen in: Surgical Endoscopy | Ausgabe 12/2020

Einloggen, um Zugang zu erhalten

Abstract

Background

The outcomes of bariatric surgery should not be evaluated only for weight loss purposes but from a wider point of view that is closer to the reality of morbidly obese patients. The study of the influence of bariatric surgery over obesity-related diseases in bariatric patients is worthwhile.

Methods

We present a cohort study of 329 patients who underwent either laparoscopic sleeve gastrectomy (LSG: 165 patients) or laparoscopic gastric bypass (LRYGBP: 164). We analyzed complication rate, comorbidities and weight loss evolution.

Results

Both groups were comparable in demographic characteristics at baseline. Significant statistical differences were found in length of hospital stay and operative time (both were lower in the LSG group). Bleeding and wound infection were higher in the LRYGBP group, as it happened with intestinal occlusion as a late complication (p < 0.05). After a 5-year follow-up, the percentage of excess weight loss (%EWL) was higher in gastric bypass than sleeve gastrectomy (p = 0.01) but there was no statistical difference in percentage of total weight loss (%TWL) (p = 0.2). The resolution of comorbidities was similar in both groups except for dyslipidemia, which resolution was significantly higher in the gastric bypass group (p = 0.005). Metabolic syndrome (MeTS) resolution was similar in both groups.

Conclusions

Sleeve gastrectomy and gastric bypass achieve similar outcomes in hypertension, type 2 diabetes, obstructive sleep apnea and MeTS resolution even when there is weight regain. Although gastric bypass achieves higher weight loss in morbid obese patients, complication rates are also higher compared to those of sleeve gastrectomy. Thus, the appropriate procedure should be tailored based on patient factors and comorbidities, but also on surgeon comfort level and experience.
Literatur
1.
Zurück zum Zitat Ng M, Fleming TRM (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384:766CrossRef Ng M, Fleming TRM (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384:766CrossRef
2.
Zurück zum Zitat Zhang Y, Ju W, Sun X, Cao Z, Xinsheng X, Liu D et al (2015) Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass for morbid obesity and related comorbidities: a meta-analysis of 21 studies. Obes Surg 25:19–26CrossRef Zhang Y, Ju W, Sun X, Cao Z, Xinsheng X, Liu D et al (2015) Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass for morbid obesity and related comorbidities: a meta-analysis of 21 studies. Obes Surg 25:19–26CrossRef
3.
Zurück zum Zitat Deitel M, Crosby RD, Gagner M (2018) The first international consensus summit for sleeve gastrectomy. Obes Surg 18:487–496CrossRef Deitel M, Crosby RD, Gagner M (2018) The first international consensus summit for sleeve gastrectomy. Obes Surg 18:487–496CrossRef
4.
Zurück zum Zitat Dogan K, Gadiot RP, Aarts EO, Betzel B, van Laarhoven CJ, Biter LU et al (2015) Effectiveness and safety of sleeve gastrectomy, gastric bypass and adjustable gastric banding in morbidly obese patients: a multicenter, retrospective, matched cohort study. Obes Surg 25:1110–1118CrossRef Dogan K, Gadiot RP, Aarts EO, Betzel B, van Laarhoven CJ, Biter LU et al (2015) Effectiveness and safety of sleeve gastrectomy, gastric bypass and adjustable gastric banding in morbidly obese patients: a multicenter, retrospective, matched cohort study. Obes Surg 25:1110–1118CrossRef
5.
Zurück zum Zitat Chang SH, Cr S, Song J, Varela JE, Eaogon CJ, Colditz GA (2014) The effectiveness and risks of bariatric surgery: and updated systematic review and meta-analysis, 2003–2012. JAMA Surg 149:275–287CrossRef Chang SH, Cr S, Song J, Varela JE, Eaogon CJ, Colditz GA (2014) The effectiveness and risks of bariatric surgery: and updated systematic review and meta-analysis, 2003–2012. JAMA Surg 149:275–287CrossRef
6.
Zurück zum Zitat Trastulli S, Desiderio J, Guarino S, Cirocchi R, Scalercio V, Noya G et al (2013) Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. Surg Obes Relat Dis 9:816–829CrossRef Trastulli S, Desiderio J, Guarino S, Cirocchi R, Scalercio V, Noya G et al (2013) Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. Surg Obes Relat Dis 9:816–829CrossRef
7.
Zurück zum Zitat Leyba JL, Navarrete Llopis S, Navarrete Aulestia S (2014) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study with 5 years of follow-up. Obes Surg 24:2094–2098CrossRef Leyba JL, Navarrete Llopis S, Navarrete Aulestia S (2014) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study with 5 years of follow-up. Obes Surg 24:2094–2098CrossRef
8.
Zurück zum Zitat Alexandrou A, Athanasiou A, Michalinos A, Felekouras E, Tesigris C, Diamantis T (2015) Laparoscopic sleeve gastrectomy for morbid obesity: 5-year results. Am J surg 209:230–234CrossRef Alexandrou A, Athanasiou A, Michalinos A, Felekouras E, Tesigris C, Diamantis T (2015) Laparoscopic sleeve gastrectomy for morbid obesity: 5-year results. Am J surg 209:230–234CrossRef
9.
Zurück zum Zitat Hong JS, Kim WW, Han SM (2015) Five year results of laparoscopic sleeve gastrectomy in Korean patients with lower body mass index (30–35 kg m/2). Obes Surg 25:824–829CrossRef Hong JS, Kim WW, Han SM (2015) Five year results of laparoscopic sleeve gastrectomy in Korean patients with lower body mass index (30–35 kg m/2). Obes Surg 25:824–829CrossRef
10.
Zurück zum Zitat Brethauer SA, Kim J, el Chaar M, Papasavas P, Eisenberg D, Rogers A et al (2015) Standardized outcomes reporting in metabolic and bariatric surgery. Surg Obes Relat Dis 11:489–506CrossRef Brethauer SA, Kim J, el Chaar M, Papasavas P, Eisenberg D, Rogers A et al (2015) Standardized outcomes reporting in metabolic and bariatric surgery. Surg Obes Relat Dis 11:489–506CrossRef
11.
Zurück zum Zitat Conference NIH (1991) Gastrointestinal surgery for severe obesity. Consensus development conference panel. Ann Intern Med 115:956–961CrossRef Conference NIH (1991) Gastrointestinal surgery for severe obesity. Consensus development conference panel. Ann Intern Med 115:956–961CrossRef
12.
Zurück zum Zitat Zimmet P, Alberti KSM (2005) Una nueva definición mundial del síndrome metabólico propuesta por la Federación Internacional de Diabetes: fundamento y resultados. Rev Esp Cardiol 58:1371–1376CrossRef Zimmet P, Alberti KSM (2005) Una nueva definición mundial del síndrome metabólico propuesta por la Federación Internacional de Diabetes: fundamento y resultados. Rev Esp Cardiol 58:1371–1376CrossRef
13.
Zurück zum Zitat Baltasar A, Bou R, Del Río J, Bengoechea M, Escriva C, Miro J et al (1997) Cirugía Bariátrica: Resultados a largo plazo de la gastrectomía vertical anillada. Cir Esp 62:175–179 Baltasar A, Bou R, Del Río J, Bengoechea M, Escriva C, Miro J et al (1997) Cirugía Bariátrica: Resultados a largo plazo de la gastrectomía vertical anillada. Cir Esp 62:175–179
14.
Zurück zum Zitat Deitel MGM (2003) Recommendations for reporting weight loss. Obes Surg 13:159–160CrossRef Deitel MGM (2003) Recommendations for reporting weight loss. Obes Surg 13:159–160CrossRef
15.
Zurück zum Zitat Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D, Borbély Y et al (2018) Effect of laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass on weight loss in patients with morbid obesity. The SM-BOSS randomized clinical trial. JAMA 319:255–265CrossRef Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D, Borbély Y et al (2018) Effect of laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass on weight loss in patients with morbid obesity. The SM-BOSS randomized clinical trial. JAMA 319:255–265CrossRef
16.
Zurück zum Zitat Salminem P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P, Hurme S et al (2018) Effect of laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass on weight loss at 5 years among patients with morbid obesity. The SLEEVEPASS randomiced clinical trial. JAMA 319:241–254CrossRef Salminem P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P, Hurme S et al (2018) Effect of laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass on weight loss at 5 years among patients with morbid obesity. The SLEEVEPASS randomiced clinical trial. JAMA 319:241–254CrossRef
17.
Zurück zum Zitat Diamantis T, Apostolou KG, Alexandrou A, Griniatsos J, Felekouras E, Tsigris C (2014) Review of long-term weight loss results after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 10:177–183CrossRef Diamantis T, Apostolou KG, Alexandrou A, Griniatsos J, Felekouras E, Tsigris C (2014) Review of long-term weight loss results after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 10:177–183CrossRef
18.
Zurück zum Zitat Himpens J, Dobbeleir J, Peeters G (2010) Long-term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg 252:319–324CrossRef Himpens J, Dobbeleir J, Peeters G (2010) Long-term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg 252:319–324CrossRef
19.
Zurück zum Zitat Li J, Lai D, Wu D (2016) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy to treat morbid obesity-related comorbidities: a systematic review and meta-analysis. Obes Surg 26:429–442CrossRef Li J, Lai D, Wu D (2016) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy to treat morbid obesity-related comorbidities: a systematic review and meta-analysis. Obes Surg 26:429–442CrossRef
20.
Zurück zum Zitat Rondelli F, Bugiantella W, Vedovati MC, Mariani E, Balzarotti Canger RC, Federici S et al (2017) Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy: a retrospective multicenter comparision between early and long term post-operative outcomes. Int J Surg 37:36–41CrossRef Rondelli F, Bugiantella W, Vedovati MC, Mariani E, Balzarotti Canger RC, Federici S et al (2017) Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy: a retrospective multicenter comparision between early and long term post-operative outcomes. Int J Surg 37:36–41CrossRef
21.
Zurück zum Zitat Ignat M, Vix M, Imad I, D’Urso A, Perretta S, Marescaux J, et al (2017) Randomized trial of Roux-en-Y gastric bypass versus sleeve gastrectomy in achieving excess weight loss. Br J Surg 104:248–256CrossRef Ignat M, Vix M, Imad I, D’Urso A, Perretta S, Marescaux J, et al (2017) Randomized trial of Roux-en-Y gastric bypass versus sleeve gastrectomy in achieving excess weight loss. Br J Surg 104:248–256CrossRef
22.
Zurück zum Zitat Parikh M, Issa R, McCrillis A, Saunders JK, Ude-Welcome A, Gagner M (2013) Surgical strategies that may decrease leak after laparoscopic sleeve gastrectomy: a systematic review and meta-analysis of 9991 cases. Ann Surg 257:231–237CrossRef Parikh M, Issa R, McCrillis A, Saunders JK, Ude-Welcome A, Gagner M (2013) Surgical strategies that may decrease leak after laparoscopic sleeve gastrectomy: a systematic review and meta-analysis of 9991 cases. Ann Surg 257:231–237CrossRef
23.
Zurück zum Zitat Vidal P, Ramón JM, Goday A, Benaiges D, Trillo L, Parri A et al (2013) Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy as a definitive surgical procedure for morbid obesity Mind-term results. Obes Surg 23:292–299CrossRef Vidal P, Ramón JM, Goday A, Benaiges D, Trillo L, Parri A et al (2013) Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy as a definitive surgical procedure for morbid obesity Mind-term results. Obes Surg 23:292–299CrossRef
24.
Zurück zum Zitat Zellmer JD, Mathiason MA, Kallies KJ, Kothari SN (2014) Is laparoscopic sleeve gastrectomy a lower risk bariatric procedure compared to laparoscopic Roux-en-Y gastric bypass? A meta-analysis. Am J Surg 208(6):903–910 Zellmer JD, Mathiason MA, Kallies KJ, Kothari SN (2014) Is laparoscopic sleeve gastrectomy a lower risk bariatric procedure compared to laparoscopic Roux-en-Y gastric bypass? A meta-analysis. Am J Surg 208(6):903–910
25.
Zurück zum Zitat Boza C, Gamboa C, Salinas J, Achurra P, Vega A, Pérez G (2012) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case-control study and 3 years of follow-up. Surg Obes Relat Dis 8:243–249CrossRef Boza C, Gamboa C, Salinas J, Achurra P, Vega A, Pérez G (2012) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case-control study and 3 years of follow-up. Surg Obes Relat Dis 8:243–249CrossRef
26.
Zurück zum Zitat Ma IT, Madura JA (2015) Gastrointestinal complications after bariatric surgery. Gastroenterol Hepatol 11(8):526–535 Ma IT, Madura JA (2015) Gastrointestinal complications after bariatric surgery. Gastroenterol Hepatol 11(8):526–535
27.
Zurück zum Zitat Quesada B, Kohan G, Roff H, Canullan C, Chiappetta L (2010) Management of gallstones and gallbladder disease in patients undergoing gastric bypass. World J Gastroenterol 16:2075–2079CrossRef Quesada B, Kohan G, Roff H, Canullan C, Chiappetta L (2010) Management of gallstones and gallbladder disease in patients undergoing gastric bypass. World J Gastroenterol 16:2075–2079CrossRef
28.
Zurück zum Zitat Yip S, Plank LD, Murphy R (2013) Gastric bypass and sleeve gastrectomy for type 2 diabetes: a systematic review and meta-analysis of outcomes. Obes Sur 23:1994–2003CrossRef Yip S, Plank LD, Murphy R (2013) Gastric bypass and sleeve gastrectomy for type 2 diabetes: a systematic review and meta-analysis of outcomes. Obes Sur 23:1994–2003CrossRef
29.
Zurück zum Zitat Melissas J, Koukouraki S, Ascoxilakis J, Stathaki M, Daskalakis M, Perisinakis K et al (2007) Sleeve gastrectomy: a restrictive procedure? Obes Surg 17:57–62CrossRef Melissas J, Koukouraki S, Ascoxilakis J, Stathaki M, Daskalakis M, Perisinakis K et al (2007) Sleeve gastrectomy: a restrictive procedure? Obes Surg 17:57–62CrossRef
30.
Zurück zum Zitat Braghetto I, Davanzo C, Korn O, Csendes A, Valladares H, Herrera E et al (2009) Scintigraphic evaluation of gastric emptying in obese patients submitted to sleeve gastrectomy compared to normal subjets. Obes Surg 19:1515–1521CrossRef Braghetto I, Davanzo C, Korn O, Csendes A, Valladares H, Herrera E et al (2009) Scintigraphic evaluation of gastric emptying in obese patients submitted to sleeve gastrectomy compared to normal subjets. Obes Surg 19:1515–1521CrossRef
31.
Zurück zum Zitat Rubino F, Marescaux J (2004) Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg 239:1–11CrossRef Rubino F, Marescaux J (2004) Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg 239:1–11CrossRef
32.
Zurück zum Zitat Sarkosh K, Switzer NJ, El-Hadi M, Birch DW, Shi W, Karmali S (2013) The impact of bariatric surgery on obstructive sleep apnea: a systematic review. Obes Surg 23:414–423CrossRef Sarkosh K, Switzer NJ, El-Hadi M, Birch DW, Shi W, Karmali S (2013) The impact of bariatric surgery on obstructive sleep apnea: a systematic review. Obes Surg 23:414–423CrossRef
33.
Zurück zum Zitat Nagendran M, Carlin AM, Bacal D, Genaw JA, Hawasli AA, Birkmeyer NJ et al (2015) Self-reported remission of obstructive sleep apnea following bariatric surgery: cohort study. Surg Obes Relat Dis 11:697–703CrossRef Nagendran M, Carlin AM, Bacal D, Genaw JA, Hawasli AA, Birkmeyer NJ et al (2015) Self-reported remission of obstructive sleep apnea following bariatric surgery: cohort study. Surg Obes Relat Dis 11:697–703CrossRef
34.
Zurück zum Zitat Recomendaciones de la SECO para la práctica de la cirugía bariátrica (Declaración de Salamanca) (2014). Cir Esp 75:312–314. Recomendaciones de la SECO para la práctica de la cirugía bariátrica (Declaración de Salamanca) (2014). Cir Esp 75:312–314.
35.
Zurück zum Zitat Gracia JA, Martinez M, Aguilella V, Elía M, Royo P (2007) Postoperative morbidity of biliopancreatic diversión depending on common limb length. Obes Surg 17:1306–1311CrossRef Gracia JA, Martinez M, Aguilella V, Elía M, Royo P (2007) Postoperative morbidity of biliopancreatic diversión depending on common limb length. Obes Surg 17:1306–1311CrossRef
36.
Zurück zum Zitat Larrad A, Sánchez-Cabezudo C (2004) Quality indicators in bariatric surgery and criteria for long-term success. CirEsp 75:301–304 Larrad A, Sánchez-Cabezudo C (2004) Quality indicators in bariatric surgery and criteria for long-term success. CirEsp 75:301–304
37.
Zurück zum Zitat Golzarand M, Toolabi K, Farid R (2017) The bariuatric surgery and weight losing: a meta-analysis in the long- and very long-term effects of laparoscopicadjustable gastric banding, laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy on weight loss in adults. Surg Endosc 11:4331–4345CrossRef Golzarand M, Toolabi K, Farid R (2017) The bariuatric surgery and weight losing: a meta-analysis in the long- and very long-term effects of laparoscopicadjustable gastric banding, laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy on weight loss in adults. Surg Endosc 11:4331–4345CrossRef
Metadaten
Titel
Metabolic effects and outcomes of sleeve gastrectomy and gastric bypass: a cohort study
verfasst von
B. Calvo
J. A. Gracia
M. A. Bielsa
M. Martínez
Publikationsdatum
01.12.2020
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 12/2020
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-019-07355-z

Weitere Artikel der Ausgabe 12/2020

Surgical Endoscopy 12/2020 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.