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Erschienen in: Medical Oncology 4/2007

01.12.2007 | Case

Metachronous non-Hodgkin's lymphoma in a patient with localized prostate cancer

verfasst von: Mehmet E. Kalender, Alper Sevinc, Ediz Tutar, Suleyman Buyukberber, Celalettin Camci

Erschienen in: Medical Oncology | Ausgabe 4/2007

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Abstract

Introduction

A higher frequency of second malignancies is observed in patients with prostate cancer. We report a case of indolent non-Hodgkin's lymphoma diagnosed 2 years after prostate carcinoma.

Case report

A 65-year-old man with diagnosis of localized prostate adenocarcinoma was presented with fatigue 2 years after prostatectomy operation. Abdominal ultrasonography showed hepatomegaly and paraaortocaval, parailiac, and perivascular multiple lymph nodes. The complete blood count revealed anemia and thrombocytopenia. Bone marrow biopsy demonstrated small lymphocytic lymphoma.

Conclusion

Lymphoma should be suspected in cases with newly appeared adenopathy and/or cytopenias during follow-up. In patients with clinically organ-confined prostate cancer, indolent lymphoma should be in the differential diagnosis of newly appeared lymphadenopathy.
Literatur
1.
Zurück zum Zitat Drinis S, Finkelstein MP, Tortorelis DG, Konno S, Choudhury MS. Five-year prognosis after radical prostatectomy in a patient with localized prostate cancer and incidental non-Hodgkin's lymphoma. Urol Int 2001;66:105–7.PubMedCrossRef Drinis S, Finkelstein MP, Tortorelis DG, Konno S, Choudhury MS. Five-year prognosis after radical prostatectomy in a patient with localized prostate cancer and incidental non-Hodgkin's lymphoma. Urol Int 2001;66:105–7.PubMedCrossRef
2.
Zurück zum Zitat Eisenberger CF, Walsh PC, Eisenberger MA, Chow NH, Partin AW, Mostwin JL, Marshall FF, Epstein JI, Schoenberg M. Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer. Urology 1999;53:175–9.PubMedCrossRef Eisenberger CF, Walsh PC, Eisenberger MA, Chow NH, Partin AW, Mostwin JL, Marshall FF, Epstein JI, Schoenberg M. Incidental non-Hodgkin's lymphoma in patients with localized prostate cancer. Urology 1999;53:175–9.PubMedCrossRef
3.
Zurück zum Zitat Mattos Dos Santos R, Aparecida Rainho C, Carlos Souza Trindade J, Carlos Souza Trindade Filho J, De Lauro Viana Camargo J, Regina Rogatto S. Genotyping of AR and PSA polymorphisms in a patient with Klinefelter syndrome, non-Hodgkin lymphoma, and adenocarcinoma of the prostate. Cancer Genet Cytogenet 2004;153:165–9.PubMedCrossRef Mattos Dos Santos R, Aparecida Rainho C, Carlos Souza Trindade J, Carlos Souza Trindade Filho J, De Lauro Viana Camargo J, Regina Rogatto S. Genotyping of AR and PSA polymorphisms in a patient with Klinefelter syndrome, non-Hodgkin lymphoma, and adenocarcinoma of the prostate. Cancer Genet Cytogenet 2004;153:165–9.PubMedCrossRef
4.
Zurück zum Zitat Zanzi I, Stark R. Detection of a non-Hodgkin's lymphoma by capromab pendetide scintigraphy (ProstaScint) in a patient with prostate carcinoma. Urology 2002;60:514.PubMedCrossRef Zanzi I, Stark R. Detection of a non-Hodgkin's lymphoma by capromab pendetide scintigraphy (ProstaScint) in a patient with prostate carcinoma. Urology 2002;60:514.PubMedCrossRef
5.
Zurück zum Zitat Carson HJ. Unexpected synchronous non-Hodgkin's lymphoma encountered during the treatment of a previously-diagnosed carcinoma: report of three cases. Leuk Lymphoma 1996;23:625–9.PubMed Carson HJ. Unexpected synchronous non-Hodgkin's lymphoma encountered during the treatment of a previously-diagnosed carcinoma: report of three cases. Leuk Lymphoma 1996;23:625–9.PubMed
6.
Zurück zum Zitat Terris MK, Hausdorff J, Freiha FS. Hematolymphoid malignancies diagnosed at the time of radical prostatectomy. J Urol 1997;158:1457–9.PubMedCrossRef Terris MK, Hausdorff J, Freiha FS. Hematolymphoid malignancies diagnosed at the time of radical prostatectomy. J Urol 1997;158:1457–9.PubMedCrossRef
7.
Zurück zum Zitat Miura S, Ishiguro Y, Tsushima K, Murata Y, Munakata A, Kamata Y. Quadruple malignant neoplasms composed of gastric carcinoid, prostatic carcinoma, malignant lymphoma, and malignant mesothelioma in a short-term [Article in Japanese]. Nippon Naika Gakkai Zasshi 2000;89:1654–6.PubMed Miura S, Ishiguro Y, Tsushima K, Murata Y, Munakata A, Kamata Y. Quadruple malignant neoplasms composed of gastric carcinoid, prostatic carcinoma, malignant lymphoma, and malignant mesothelioma in a short-term [Article in Japanese]. Nippon Naika Gakkai Zasshi 2000;89:1654–6.PubMed
8.
Zurück zum Zitat Kawakami S, Fukui I, Yonese J, et al. Multiple primary malignant neoplasms associated with prostate cancer in 312 consecutive cases. Urol Int 1997;59:243–7.PubMedCrossRef Kawakami S, Fukui I, Yonese J, et al. Multiple primary malignant neoplasms associated with prostate cancer in 312 consecutive cases. Urol Int 1997;59:243–7.PubMedCrossRef
9.
Zurück zum Zitat Pawlish KS, Schottenfeld D, Severson R et al. Risk of multiple primary cancers in prostate cancer patients in the Detroit metropolitan area: a retrospective cohort study. Prostate 1997;33: 75–86.PubMedCrossRef Pawlish KS, Schottenfeld D, Severson R et al. Risk of multiple primary cancers in prostate cancer patients in the Detroit metropolitan area: a retrospective cohort study. Prostate 1997;33: 75–86.PubMedCrossRef
10.
Zurück zum Zitat Moertel CG, Dockerty MB, Baggenstoss AH. Multiple primary malignant neoplasms. I. Introduction and presentation of data. Cancer 1961;14:221–30.PubMedCrossRef Moertel CG, Dockerty MB, Baggenstoss AH. Multiple primary malignant neoplasms. I. Introduction and presentation of data. Cancer 1961;14:221–30.PubMedCrossRef
11.
Zurück zum Zitat Wazait HD, Al-Buheissi SZ, Dudderidge T, Patel HR, Jarmulowicz M, Pigott K, Miller RA. Rare case of primary lymphoma of the prostate: giving the patient the benefit of the doubt. Urol Int 2003;71:338–40.PubMedCrossRef Wazait HD, Al-Buheissi SZ, Dudderidge T, Patel HR, Jarmulowicz M, Pigott K, Miller RA. Rare case of primary lymphoma of the prostate: giving the patient the benefit of the doubt. Urol Int 2003;71:338–40.PubMedCrossRef
12.
Zurück zum Zitat Ochoa Undargarain O, Hermida Perez JA, de Ochoa Montes Oca J, Felix Leon JM. Well-differentiated lymphocytic lymphoma of the prostate. Case report and bibliographic review [Article in Spanish]. Arch Esp Urol 2006;59:538–41.PubMed Ochoa Undargarain O, Hermida Perez JA, de Ochoa Montes Oca J, Felix Leon JM. Well-differentiated lymphocytic lymphoma of the prostate. Case report and bibliographic review [Article in Spanish]. Arch Esp Urol 2006;59:538–41.PubMed
13.
Zurück zum Zitat Alvarez CA, Rodriguez BI, Perez LA. Primary diffuse large B-cell lymphoma of the prostate in a young patient. Int Braz J Urol 2006;32:64–5.PubMedCrossRef Alvarez CA, Rodriguez BI, Perez LA. Primary diffuse large B-cell lymphoma of the prostate in a young patient. Int Braz J Urol 2006;32:64–5.PubMedCrossRef
14.
Zurück zum Zitat Miyahara T, Oyabul Y, Hayashi T, Shimizu S, Tanaka H, Matsuoka K. A case of malignant lymphoma of the prostate [Article in Japanese]. Nippon Hinyokika Gakkai Zasshi 2005;96:644–6.PubMed Miyahara T, Oyabul Y, Hayashi T, Shimizu S, Tanaka H, Matsuoka K. A case of malignant lymphoma of the prostate [Article in Japanese]. Nippon Hinyokika Gakkai Zasshi 2005;96:644–6.PubMed
15.
Zurück zum Zitat Antunes AA, Dall'Oglio M, Srougi M. Primary lymphoma of the prostate: a rare cause of urinary obstruction. Int Braz J Urol 2004;30:410–2.PubMed Antunes AA, Dall'Oglio M, Srougi M. Primary lymphoma of the prostate: a rare cause of urinary obstruction. Int Braz J Urol 2004;30:410–2.PubMed
16.
Zurück zum Zitat Lin ZC, Xhen YP, Wang SY, Zhang XL. Non-Hodgkin's lymphoma of the prostate: report of one case [Article in Chinese]. Di Yi Jun Yi Da Xue Xue Bao 2004;24:308–9.PubMed Lin ZC, Xhen YP, Wang SY, Zhang XL. Non-Hodgkin's lymphoma of the prostate: report of one case [Article in Chinese]. Di Yi Jun Yi Da Xue Xue Bao 2004;24:308–9.PubMed
17.
Zurück zum Zitat Bouet R, Thwaites D, Harris SB, Young AN, Issa MM. Asymptomatic follicular lymphoma of the prostate discovered by abnormal digital rectal examination. J Urol 2004;171:795–6.PubMedCrossRef Bouet R, Thwaites D, Harris SB, Young AN, Issa MM. Asymptomatic follicular lymphoma of the prostate discovered by abnormal digital rectal examination. J Urol 2004;171:795–6.PubMedCrossRef
18.
Zurück zum Zitat Leewansangtong S, Crawford ED. Prostate. In: Haskell CM, editor. Cancer treatment. Pennsylvania: W.B. Saunders Company; 2001. p. 806–28. Leewansangtong S, Crawford ED. Prostate. In: Haskell CM, editor. Cancer treatment. Pennsylvania: W.B. Saunders Company; 2001. p. 806–28.
19.
Zurück zum Zitat Weir EG, Epstein JI. Incidental small lymphocytic lymphoma/chronic lymphocytic leukemia in pelvic lymph nodes excised at radical prostatectomy. Arch Pathol Lab Med 2003;127:567–72.PubMed Weir EG, Epstein JI. Incidental small lymphocytic lymphoma/chronic lymphocytic leukemia in pelvic lymph nodes excised at radical prostatectomy. Arch Pathol Lab Med 2003;127:567–72.PubMed
20.
Zurück zum Zitat Cellini N, Luzi S, Mantini G, Mattiucci GC, Morganti AG, Digesu C, Bavasso A, Deodato F, Smaniotto D, Valentini V. Lymphatic drainage and CTV in carcinoma of the prostate. Rays 2003;28:337–41.PubMed Cellini N, Luzi S, Mantini G, Mattiucci GC, Morganti AG, Digesu C, Bavasso A, Deodato F, Smaniotto D, Valentini V. Lymphatic drainage and CTV in carcinoma of the prostate. Rays 2003;28:337–41.PubMed
Metadaten
Titel
Metachronous non-Hodgkin's lymphoma in a patient with localized prostate cancer
verfasst von
Mehmet E. Kalender
Alper Sevinc
Ediz Tutar
Suleyman Buyukberber
Celalettin Camci
Publikationsdatum
01.12.2007
Verlag
Humana Press Inc
Erschienen in
Medical Oncology / Ausgabe 4/2007
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-007-0024-x

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